Tumor hypoxia in rectal cancer – improving radiotherapy outcome by merging kinomics and functional magnetic resonance imaging
- Prosjektnummer
- 2012002
- Ansvarlig person
- Anne Hansen Ree
- Institusjon
- Akershus universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 5. Treatment Developement
Tumor phosphatidylinositol 3-kinase signaling in therapy resistance and metastatic dissemination of rectal cancer: opportunities for signaling-adapted therapies.
Crit Rev Oncol Hematol 2015 Jul;95(1):114-24. Epub 2015 jan 12
PMID: 25624177
MRI volumetry for prediction of tumour response to neoadjuvant chemotherapy followed by chemoradiotherapy in locally advanced rectal cancer.
Br J Radiol 2015 Jul;88(1051):20150097. Epub 2015 apr 22
PMID: 25899892
Personalized radiotherapy: concepts, biomarkers and trial design.
Br J Radiol 2015 Jul;88(1051):20150009. Epub 2015 mai 20
PMID: 25989697
Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer.
BMC Cancer 2015;15():543. Epub 2015 jul 24
PMID: 26205955
Sulfamate inhibitor S4 influences carbonic anhydrase IX ectodomain shedding in colorectal carcinoma cells.
J Enzyme Inhib Med Chem 2016 Oct;31(5):779-86. Epub 2015 aug 5
PMID: 26244271
High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer.
Radiother Oncol 2016 Feb;118(2):393-8. Epub 2015 des 17
PMID: 26705680
Biomarkers of histone deacetylase inhibitor activity in a phase 1 combined-modality study with radiotherapy.
PLoS One 2014;9(2):e89750. Epub 2014 feb 25
PMID: 24587009
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.
J Enzyme Inhib Med Chem 2014 Oct 27. Epub 2014 okt 27
PMID: 25347767
Biomarkers of treatment toxicity in combined-modality cancer therapies with radiation and systemic drugs: study design, multiplex methods, molecular networks.
Int J Mol Sci 2014;15(12):22835-56. Epub 2014 des 9
PMID: 25501337
Magnetic resonance-guided histopathology for improved accuracy of tumor response evaluation of neoadjuvant treatment in organ-infiltrating rectal cancer.
Radiother Oncol 2013 May;107(2):178-83. Epub 2013 apr 17
PMID: 23602370
Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer.
PLoS One 2013;8(5):e63723. Epub 2013 mai 10
PMID: 23675504
Design and conduct of early-phase radiotherapy trials with targeted therapeutics: lessons from the PRAVO experience.
Radiother Oncol 2013 Jul;108(1):3-16. Epub 2013 jul 3
PMID: 23830196
Differential inhibition of ex-vivo tumor kinase activity by vemurafenib in BRAF(V600E) and BRAF wild-type metastatic malignant melanoma.
PLoS One 2013;8(8):e72692. Epub 2013 aug 30
PMID: 24023633
Hypoxia-independent downregulation of hypoxia-inducible factor 1 targets by androgen deprivation therapy in prostate cancer.
Int J Radiat Oncol Biol Phys 2013 Nov 15;87(4):753-60. Epub 2013 sep 10
PMID: 24035332
Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer.
Radiat Oncol 2012;7():75. Epub 2012 mai 23
PMID: 22621752
Individualised treatment of metastatic cancer.
Tidsskr Nor Laegeforen 2012 Nov;132(21):2358-9.
PMID: 23160572
- Tone Frost Bathen Prosjektdeltaker
- Beathe Sitter Prosjektdeltaker
- Yvonne Andersson Prosjektdeltaker
- Helga Helseth Hektoen Prosjektdeltaker
- Krystyna Kotanska-grøholt Prosjektdeltaker
- Jürgen Geisler Prosjektdeltaker
- Svein Dueland Prosjektdeltaker
- Kjersti Flatmark Prosjektdeltaker
- Sigurd Folkvord Prosjektdeltaker
- Marie Grøn Sælen Prosjektdeltaker
- Anne Negard Prosjektdeltaker
- Knut Håkon Hole Prosjektdeltaker
- Therese Seierstad Prosjektdeltaker
- Arne Sigmund Borthne Prosjektdeltaker
- Christin Johansen Prosjektdeltaker
- Sebastian Meltzer Prosjektdeltaker
- Kathrine Røe Redalen Postdoktorstipendiat
- Anne Hansen Ree Prosjektleder
- Janne Sølvernes Prosjektdeltaker
- Marius Bornstein Prosjektdeltaker
- Monica Chahal-Kummen Prosjektdeltaker
- Kathrine Røe Postdoktorstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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