Role of tumor initiating cells in early breast cancer development
- Prosjektnummer
- 2012056
- Ansvarlig person
- Therese Sørlie
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Karrierestipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 2. Aetiology
NEI
Nei
Comparable cancer-relevant mutation profiles in synchronous ductal carcinoma in situ and invasive breast cancer.
Cancer Rep (Hoboken) 2020 Jun;3(3):e1248. Epub 2020 mai 28
PMID: 32671987
Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions.
NPJ Breast Cancer 2020;6():26. Epub 2020 jun 17
PMID: 32577501
Re-definition of claudin-low as a breast cancer phenotype.
Nat Commun 2020 04 14;11(1):1787. Epub 2020 apr 14
PMID: 32286297
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment.
Nat Commun 2019 Dec 03;10(1):5499. Epub 2019 des 3
PMID: 31796750
Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers.
Breast Cancer Res 2019 07 31;21(1):85. Epub 2019 jul 31
PMID: 31366361
A Bayesian two-way latent structure model for genomic data integration reveals few pan-genomic cluster subtypes in a breast cancer cohort.
Bioinformatics 2019 Dec 01;35(23):4886-4897.
PMID: 31077301
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue.
J Mammary Gland Biol Neoplasia 2019 Jun;24(2):163-175. Epub 2019 jan 6
PMID: 30613869
The tankyrase inhibitor G007-LK inhibits small intestine LGR5
Biol Res 2018 Jan 09;51(1):3. Epub 2018 jan 9
PMID: 29316982
Intrinsic subtypes and benefit from postmastectomy radiotherapy in node-positive premenopausal breast cancer patients who received adjuvant chemotherapy - results from two independent randomized trials.
Acta Oncol 2018 Jan;57(1):38-43. Epub 2017 nov 25
PMID: 29172851
Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up.
Breast Cancer Res 2017 Nov 14;19(1):120. Epub 2017 nov 14
PMID: 29137653
Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition.
Cancer Discov 2017 10;7(10):1098-1115. Epub 2017 jun 26
PMID: 28652380
Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer.
Cell Rep 2016 Jul 26;16(4):1166-79. Epub 2016 jul 7
PMID: 27396337
The Impact of Gene Expression Patterns in Breast Cancer.
Clin Chem 2016 Aug;62(8):1150-1. Epub 2016 mar 28
PMID: 27022070
From autonomy to community; new perspectives on tumorigenicity and therapy resistance.
Cancer Treat Rev 2015 Dec;41(10):809-13. Epub 2015 okt 20
PMID: 26519005
The prognostic role of HER2 expression in ductal breast carcinoma in situ (DCIS); a population-based cohort study.
BMC Cancer 2015;15():468. Epub 2015 jun 11
PMID: 26062614
A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5.
Dev Biol 2015 Aug 15;404(2):35-48. Epub 2015 mai 21
PMID: 26003047
Glycan-related gene expression signatures in breast cancer subtypes; relation to survival.
Mol Oncol 2015 Apr;9(4):861-76. Epub 2015 jan 14
PMID: 25655580
Differential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer xenograft.
PLoS One 2014;9(11):e113278. Epub 2014 nov 24
PMID: 25419568
Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy.
Br J Surg 2014 Jul;101(8):925-38. Epub 2014 mai 21
PMID: 24849143
Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer.
Acta Oncol 2014 Oct;53(10):1337-46. Epub 2014 jun 24
PMID: 24957550
Development and validation of a gene profile predicting benefit of postmastectomy radiotherapy in patients with high-risk breast cancer: a study of gene expression in the DBCG82bc cohort.
Clin Cancer Res 2014 Oct 15;20(20):5272-80. Epub 2014 aug 22
PMID: 25149560
Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status.
BMC Cancer 2014;14():211. Epub 2014 mar 19
PMID: 24645668
Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE).
Methods Mol Biol 2014;1105():315-24.
PMID: 24623239
Interplay of choline metabolites and genes in patient-derived breast cancer xenografts.
Breast Cancer Res 2014;16(1):R5. Epub 2014 jan 21
PMID: 24447408
Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts.
Mol Oncol 2013 Feb;7(1):130-42. Epub 2012 okt 23
PMID: 23142657
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins.
Mol Oncol 2013 Jun;7(3):704-18. Epub 2013 mar 19
PMID: 23562353
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection.
Virchows Arch 2013 Dec;463(6):775-86. Epub 2013 okt 8
PMID: 24100522
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study.
BMC Cancer 2013;13():512. Epub 2013 okt 30
PMID: 24171825
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity.
Proc Natl Acad Sci U S A 2012 Apr;109(16):6124-9. Epub 2012 mar 27
PMID: 22454501
Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement.
Ann Oncol 2012 Dec;23(12):2997-3006.
PMID: 23166150
Deciphering molecular heterogeneity and relevance of subtypes in breast cancer progression
- Disputert:
- mars 2020
- Hovedveileder:
- Therese Sørlie
Molecular and functional analysis of tumor heterogeneity in breast cancer xenograft models
- Disputert:
- juni 2016
- Hovedveileder:
- Therese Sørlie
Transcriptomics and metabolomics of breast cancer to improve the understanding of disease mechanisms and treatment response
- Disputert:
- mai 2012
- Hovedveileder:
- Therese Sørlie
- Margit Riis Prosjektdeltaker
- Tonje Sofie Dalen Prosjektdeltaker
- David Swanson Prosjektdeltaker
- Arnoldo Frigessi Prosjektdeltaker
- Christian Fougner Prosjektdeltaker
- Anne Marthe Fosdahl Postdoktorstipendiat (annen finansiering)
- Jens Henrik Norum Forsker (annen finansiering)
- Tonje Gulbrandsen Lien Postdoktorstipendiat (annen finansiering)
- Helga Bergholtz Doktorgradsstipendiat (finansiert av denne bevilgning)
- Therese Sørlie Prosjektleder
- Nirma Skrbo Doktorgradsstipendiat (annen finansiering)
- Kristin Andersen Biveileder
- Helene Zell Thime Prosjektdeltaker
- Christian Landaas Fougner Prosjektdeltaker
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