eRapport

Nasjonal satsing - NORSMI - alvorlig psykiske lidelser.

Prosjekt
Prosjektnummer
2012132
Ansvarlig person
Ole A. Andreassen
Institusjon
Oslo universitetssykehus HF
Prosjektkategori
Nasjonal satsning - infrastruktur
Helsekategori
Mental Health
Forskningsaktivitet
2. Aetiology, 5. Treatment Developement
Rapporter
2017 - sluttrapport
NORSMI er en aktiv landsdekkende forskningsorganisasjon hvor regionale nettverk og samarbeidsprosjekt er integrert, og det er etablert som en arena for nasjonal prosjektutvikling. Rutiner for administrasjon, informasjonsflyt og koordinering er innarbeidet. Vi har brukt midler til fellesmøter, koordinering, database – og biobanktjenester, samt opplæring og kurs. NORSMI nettverket har som formål å styrke satsingen på forskning innen alvorlige psykiske lidelser i Norge, gjennom koordinering av prosjekter, bidra til felles kvalitetssikring og ekspertise, samt bidra med infrastruktur innen protokoller, biobank og database service. Resultater av satsingen har vært oppstart av en serie nasjonale multi-senter studier innen søvn vansker ved psykiske lidelser, tidlige debut faktorer, somatisk helse og fysisk trening, medikamentell behandling, forebygging, samt flere årsaks- og mekanismestudier innen genetikk og hjerneavbildning. Flere av deltakende sykehus i nettverket er aktive i det avsluttede NASATS prosjekt, Det er utviklet et fellesprosjekt på implementering av en algoritme for bedre oppfølging av fysisk helse innen denne pasientgruppen. NORSMI har satset på koordineringa av nye studier av somatisk helse og fysisk trening, og nå er flere prosjekter igangsatt. I tillegg har grupper i samarbeidet blitt med i EU finansierte internasjonale prosjekt. Nettverket har gjennomført et utviklingsarbeid der en kartlegger symptomer ved bruk av objektive målemetoder som aktigrafi der en registerer bevegelsesmønster og tempo til pasienten. I tillegg har vi flere grupper som utvikler apper til smarttelefoner for forenklet data innhenting samt bedre registrering av symptom og forløp over tid. Det er også internasjonalt samarbeid innen denne satsingen. Ved hjelp av tett samarbeid har vi fullført flere studier av arvelige faktorer, og nye metoder for å oppdage slike. Vi har funnet faktorer som er viktige for sykdomsutvikling, og forløp over tid, samt hvordan behandling påvirker utfall. Vi har etablert et samarbeid innen epidemiologiske metoder for studier av komorbiditet mellom hjertekar sykdom og psykisk helse, og i samarbeid med forskningsgruppene på Folkehelseinstituttet er det igangsatt prosjekter basert på data fra nasjonale pasientregistre, og nordiske satsinger. Vi har oppdatert og revidert felles minsteprotokoll etter ett års bruk, og etablert formalia for inklusjon ved hjelp av åpne samtykker. Vi arbeider videre med muligheten for et kvalitetsregister. Gjennom bedre samordning, felles protokoller og infrastuktur har de deltakende miljøene økt sin vitenskapelige produksjon, og nettverksmedlemmene har hatt en omfattende publisering i internasjonale tidsskrift. Prosjektet har gitt ny kunnskap om årsaker til alvorlige psykiske lidelser - bidra til utvikling av bedre behandling. Vi har utviklet en serie med prosjekter som har bidratt til bedre forskning i helsetjenesten, og dermed bedre kvalitet. Det er etablert internasjonale nettverk. Vi har fått ny kunnskap om intervensjoner og behandling, som kan brukes i klinisk virksomhet. I tillegg har prosjektet gitt innsyn i tegn og karakteristika i tidlig fase av lidelsen. Dette kan brukes i klinikken til tidlig oppdagelse, og dermed bedre behandling.
2016
NORSMI er en landsdekkende forskningsorganisasjon hvor regionale nettverk og samarbeidsprosjekt er integrert. Det er en aktiv arena for nasjonal prosjektutvikling. Rutiner for administrasjon, informasjonsflyt og koordinering er innarbeidet. Vi har brukt midler til fellesmøter, koordinering, database – og biobanktjenester, opplæring og kurs.1. Tittel på NSGs nasjonale forskningssatsing/ forskningsnettverk: NORSMI – ”Norwegian Research Network in Severe Mental Illness” = Nasjonal satsing alvorlig psykiske lidelser 2. Ansvarlig Samarbeidsorgan: Helse Sør-Øst 3. Navn på leder av fagrådet: Gunnar Morken 4. Navn på koordinator: Ole A. Andreassen 5. Lenke til hjemmeside: http://oushf.fpl.nhn.no/aktuelt_/prosjekter_/Sider/norwegian-research-network-in-severe-mental-illness.aspx 6. Oversikt over forskningsgrupper som deltar i nettverket (navn på leder av forskningsgruppe og ev. navn på forskningsgruppen, institusjon) NORSMI nettverket har som formål å styrke satsingen på forskning innen alvorlige psykiske lidelser i Norge, gjennom koordinering av prosjekter, bidra til felles kvalitetssikring og ekspertise, samt bidra med infrastruktur innen protokoller, biobank og database service. 1) Ved hjelp av felles innsamling av materiale har vi fullført flere studier av arvelige faktorer ved psykiske lidelser, og har vært involvert i store, internasjonale konsortier og oppdaget genetiske varianter for alvorlige psykiske lidelser. I tillegg har vi flere hjerneavbildningsstudier på tvers av sentra. 2) Vi har avdekket kliniske og kognitive faktorer som er assosiert med for sykdomsutvikling og forløp, samt hvordan behandling påvirker utfall. 3) Flere av deltakende sykehus i nettverket er aktive i et pågående NASATS prosjekt. Dette er en multisenter studie innen søvn og tidlige varselsignal bipolar lidelse, tidlige debut faktorer. 4) Vi har en satsing på studier som integrerer somatisk helse og trening, medikamentell behandling, samt forebygging av CVD sykdom. NORSMI har koordinert studier av somatisk helse og fysisk trening, og nå er flere prosjekter igangsatt. Det siste heter Hjertefrisk, og er et fellesprosjekt på implementering av en algoritme for bedre oppfølging av somatisk helse innen denne pasientgruppen. 5) Nettverket har igangsatt studier på bruk av moderne elektroniske verktøy (eHelse). Vi har studier som kartlegger symptomer ved bruk av objektive målemetoder som actigrafi der en registrerer bevegelsesmønster og tempo til pasienten. I tillegg har vi flere grupper som utvikler apper til smarttelefoner for forenklet data innhenting samt bedre registrering av symptom og forløp over tid. Det er også internasjonalt samarbeid innen denne satsingen, og i ferd med å utvikle web baserte løsninger for storskala datainnsamling og rekruttering. 6) Vi har et samarbeid innen epidemiologiske metoder for studier av komorbiditet mellom hjertekar sykdom og psykisk helse, og i samarbeid med forskningsgrupper på Folkehelseinstituttet er det igangsatt prosjekter basert på data fra nasjonale pasientregistre.. Vi fortsetter arbeidet med muligheten for et kvalitetsregister, og har høstet erfaringer fra deltakende sykehus innen ekspertklinikker i bipolar lidelse. Protokoll: Vi har oppdatert og revidert felles minsteprotokoll etter andre års bruk, og jobber nå med en felles protokoll for hjerneavbildning. Nettverksmedlemmer har vært involvert i flere søknader, blant annet til EU. Flere søknader basert på deltakende grupper ble innvilget i 2016, inkludert støtte fra NFR (FRIMEDBIO, HELSE-EU), Helse SørØst Helse Midt og Helse Vest.
2015
NORSMI er en landsdekkende forskningsorganisasjon hvor regionale nettverk og samarbeidsprosjekt er integrert, og det er etablert som en arena for nasjonal prosjektutvikling. NORSMI nettverket har som formål å styrke satsingen på forskning innen alvorlige psykiske lidelser i Norge, gjennom koordinering av prosjekter, bidra til felles kvalitetssikring og ekspertise, samt bidra med infrastruktur innen protokoller, biobank og database service. Det foregår nå multi-senter studier innen søvnproblemer, forhold sentrale for tidlig fase av sykdommene, somatisk helse og fysisk trening, medikamentell behandling, forebygging, samt flere genetiske og hjerneavbildningsstudier. Ved hjelp av tett samarbeid i NORSMI er det fullført flere studier av arvelige faktorer, og nye metoder for å oppdage slike. Andre prosjekter har funnet faktorer som er viktige for sykdomsutvikling, og forløp over tid, samt hvordan behandling påvirker utfall. Flere av deltakende sykehus i nettverket er aktive i et pågående NASATS prosjekt, som er et hovedprosjektet til nettverket som nå er under avslutting. NORSMI har bidratt med koordineringa av nye studier av somatisk helse og fysisk trening, og nå er flere prosjekter igangsatt. Videre har nettverksmedlemmer vært involvert i flere søknader, blant annet til EU. Det arbeides nå med å utvikle et fellesprosjekt på implementering av en algoritme for bedre oppfølging av fysisk helse innen denne pasientgruppen. Medlemmer av nettverket er i gang med et utviklingsarbeid der en kartlegger symptomer ved bruk av objektive målemetoder som actigrafi hvor en registrerer bevegelsesmønster og tempo til pasienten. I tillegg har vi flere grupper som utvikler apper til smarttelefoner for forenklet datainnhenting samt bedre registrering av symptom og forløp over tid. Det er også internasjonalt samarbeid innen denne satsingen. NORSMI koordinerer et samarbeid innen epidemiologiske metoder for studier av komorbiditet mellom hjertekarsykdom og psykisk helse, og i samarbeid med forskningsgruppene på Folkehelseinstituttet er det igangsatt prosjekter basert på data fra nasjonale pasientregistre. NORSMI nettverket har også arbeider videre med muligheten for et kvalitetsregister. NORSMI har koordinert arbeid med implementering av felles minsteprotokoll og oppdatert denne etter ett års bruk. Når det gjelder praktisk drift har NORSMI en nettside, og avholder nasjonale seminarer og møter. I tillegg til prosjektarbeid og relatert aktivitet har NORSMI koordineringsgruppen regelmessige telefonkonferanser som er åpne for alle interesserte. Det ble avholdt fysiske møter for å bidra til planlegging av intervensjonsprosjekter, med fokus på ny satsing for kardiovaskulære intervensjoner. Flere PhD studenter har ferdiggjort sine arbeider og levert inn dr grad til bedømmelse, med planlagt disputas i 2016.
2014
Sammendrag: NORSMI er en aktiv landsdekkende forskningsorganisasjon hvor regionale nettverk og samarbeidsprosjekt er integrert, og er etablert som en arena for nasjonal prosjektutvikling og drift. Rutiner for administrasjon, informasjonsflyt og koordinering er innarbeidet. Vi har brukt midler til fellesmøter, koordinering, felles database – og biobanktjenester, samt opplæring og kurs. 1. Tittel på NSGs nasjonale forskningssatsing/ forskningsnettverk: NORSMI – ”Norwegian Research Network in Severe Mental Illness” = Nasjonal satsing alvorlig psykiske lidelser 2. Ansvarlig Samarbeidsorgan: Helse Sør-Øst 3. Navn på leder av fagrådet: Gunnar Morken 4. Navn på koordinator: Ole A. Andreassen 5. Lenke til hjemmeside: http://oushf.fpl.nhn.no/aktuelt_/prosjekter_/Sider/norwegian-research-network-in-severe-mental-illness.aspx 6. Oversikt over forskningsgrupper som deltar i nettverket (navn på leder av forskningsgruppe og ev. navn på forskningsgruppen, institusjon) Brita Elvevåg, Universitetssykehuset Nord-Norge, UiT Anne Høye, Universitetssykehuset Nord-Norge, UiT Gunnar Morken, St. Olavs Universitetssykehus, NTNU Arne Vaaler, St. Olavs Universitetssykehus, NTNU Erik Johnsen, Helse Bergen/Haukeland Universitetssykehus, UiB Ketil Ødegaard, Helse Bergen/Haukeland Universitetssykehus, UiB Jan O. Johannessen, Stavanger Universitetssykehus, UiS Tor K. Larsen, Stavanger Universitetssykehus, UiB Ingrid Melle, Oslo Universitetssykehus, UiO Ole A. Andreassen, Oslo Universitetssykehus, UiO Merete Øie, Sykehuset Innlandet, UiO Ted Reichborn-Kjennerud, Folkehelseinstituttet, UiO 7. Kortfattet populærvitenskapelig sammendrag av de mest sentrale samarbeidsprosjektene, samt beskrivelse av hvilken merverdi samarbeidet i nettverket har gitt (har f.eks. nettverket utarbeidet felles søknader om eksterne midler?) Vi har avsluttet et multisenterprosjekt innen ECT behandling, og denne studien ble publisert i det beste psykiatriske tidsskrift (Am J Psychiatry), og ble valgt ut av New Engl J Medicine som en av 10 viktigste kliniske artikler i psykiatri i 2014. (Schoeyen HK, Kessler U, Andreassen OA, Auestad BH, Bergsholm P, Malt UF, Morken G, Oedegaard KJ, Vaaler A. Treatment-resistant bipolar depression: a randomized controlled trial of electroconvulsive therapy versus algorithm-based pharmacological treatment. Am J Psychiatry. Epub 2014 Oct 31) Vi har videreført arbeidet med å gjennomføre multisenterstudier innen translasjonsforskning, noe som har ledet til flere «high-impact»-publikasjoner i 2014, slik som oppdagelsen av 108 nye genvarianter for schizofreni, publisert i Nature juli. Her har hele nettverket bidratt, og medforfattere fra mange av de deltakende forskergruppene. En rekke viktige artikler omkring sykdomsutvikling, forløp og behandling av alvorlige psykiske lidelser er blitt publisert basert på tverr-regionale prosjekt med bidrag fra flere deltakende forskere. Flesteparten av deltakerne i nettverket er aktive i et pågående NASATS prosjekt, som er et hovedprosjekt i nettverket i dag. Nettverkets deltakere har benyttet nettverket til å utvikle et forum for studier av somatisk helse og fysisk trening, og denne samarbeidsplattformen har ledet til igangsettelse av tre kooordinerte prosjekter. Videre har det ledet til en større NFR søknad samt en EU søknad, og flere regionale søknader har blitt samkjørt innen dette feltet. Det arbeides kontinuerlig med å utvikle flere konkrete fellesprosjekt på dette forskningsområdet. Nettverket er i gang med et utviklingsarbeid der en kartlegger symptomer ved bruk av objektive målemetoder som actigrafi der en registerer bevegelsesmønster og tempo til pasienten. I tillegg utvikles apper til smarttelefoner der en registrerer hyppighet og tempo i bruk i tillegg til at pasientene selv fører dagbøker. Det er innledet et internasjonalt samarbeid for EU søknad med dette som satsing. Satsingen på epidemiologiske aspekter har medført konkret prosjekt i Nord Norge om komorbiditet hjertekar sykdom og psykisk helse, og i samarbeid med forskningsgrupper på Folkehelseinstituttet er det igangsatt prosjekter basert på data fra nasjonale pasientregistre. Det kjøres også en medikamentstudie i nettverket, hvor flere forskningsgrupper deltar. Vi utreder også muligheten for etableringa av kvalitetsregister. Vi har tatt i bruk en ny, felles minsteprotokoll. I vedlagte publikasjonsoversikt inngår artikler med medforfattere fra flere enn en forskergruppen. 8. Oversikt over ev. innvilgede fellessøknader i 2014: en søknad hvor flere av gruppene deltar er innvilget: - Innvilget beløp pr år: 500 000 - Varighet: 3 år - Prosjektleder: Oedegaard KJ - Prosjekttittel:Effects of ECT in treatment of major depression: A prospective neuroradiological study of acute and longitudinal effects on brain structure and function - Finansieringskilde: Helse-Vest I tillegg har en rekke søknader som utgår fra enkeltgrupper men som inkluderer samarbeid med andre grupper i det nasjonale nettveblitt innvilget. 9. Avholdte nasjonale seminarer/møter/konferanser i 2014: Onsdag 7. mai 2014 et møte i Trondheim. Planlegging intervensjonsprosjekter mellom grupper involvert. Onsdag 20. august møte på Værnes. Planlegging intervensjonsprosjekter innen fysisk helse. Satelittmøter ved andre nasjonale konferanser hvor flere av deltakerne har deltatt. Månedlige telefonkonferanser. Vi holder møtene åpne for å sikre informasjonsflyt og gjensidig inspirasjon.
Vitenskapelige artikler
Weibell MA, Hegelstad WTV, Auestad B, Bramness J, Evensen J, Haahr U, Joa I, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, McGorry P, Friis S

The Effect of Substance Use on 10-Year Outcome in First-Episode Psychosis.

Schizophr Bull 2017 Jul 01;43(4):843-851.

PMID: 28199703

Bjornestad J, Hegelstad WTV, Joa I, Davidson L, Larsen TK, Melle I, Veseth M, Johannessen JO, Bronnick K

"With a little help from my friends" social predictors of clinical recovery in first-episode psychosis.

Psychiatry Res 2017 Sep;255():209-214. Epub 2017 mai 30

PMID: 28578180

Bjornestad J, Davidson L, Joa I, Larsen TK, Hegelstad WTV, Langeveld J, Veseth M, Melle I, Johannessen JO, Bronnick K

Antipsychotic treatment: experiences of fully recovered service users.

J Ment Health 2017 Jun;26(3):264-270. Epub 2017 mar 1

PMID: 28602144

Yeisen RAH, Bjornestad J, Joa I, Johannessen JO, Opjordsmoen S

Experiences of antipsychotic use in patients with early psychosis: a two-year follow-up study.

BMC Psychiatry 2017 Aug 22;17(1):299. Epub 2017 aug 22

PMID: 28830453

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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Nat Genet 2017 Jan;49(1):27-35. Epub 2016 nov 21

PMID: 27869829

Bjoerke-Bertheussen J, Schoeyen H, Andreassen OA, Malt UF, Oedegaard KJ, Morken G, Sundet K, Vaaler AE, Auestad B, Kessler U

Right unilateral electroconvulsive therapy does not cause more cognitive impairment than pharmacologic treatment in treatment-resistant bipolar depression: A 6-month randomized controlled trial follow-up study.

Bipolar Disord 2017 Dec 21. Epub 2017 des 21

PMID: 29267990

Krane-Gartiser K, Vaaler AE, Fasmer OB, Sørensen K, Morken G, Scott J

Variability of activity patterns across mood disorders and time of day.

BMC Psychiatry 2017 Dec 19;17(1):404. Epub 2017 des 19

PMID: 29258468

Bauer M, Glenn T, Alda M, Aleksandrovich MA, Andreassen OA, Angelopoulos E, Ardau R, Ayhan Y, Baethge C, Bharathram SR, Bauer R, Baune BT, Becerra-Palars C, Bellivier F, Belmaker RH, Berk M, Bersudsky Y, Bicakci S, Birabwa-Oketcho H, Bjella TD, Bossini L, Cabrera J, Cheung EYW, Del Zompo M, Dodd S, Donix M, Etain B, Fagiolini A, Fountoulakis KN, Frye MA, Gonzalez-Pinto A, Gottlieb JF, Grof P, Harima H, Henry C, Isometsä ET, Janno S, Kapczinski F, Kardell M, Khaldi S, Kliwicki S, König B, Kot TL, Krogh R, Kunz M, Lafer B, Landén M, Larsen ER, Lewitzka U, Licht RW, Lopez-Jaramillo C, MacQueen G, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I, Meza-Urzúa F, Yee Ming M, Monteith S, Morken G, Mosca E, Munoz R, Mythri SV, Nacef F, Nadella RK, Nery FG, Nielsen RE, O'Donovan C, Omrani A, Osher Y, Østermark Sørensen H, Ouali U, Pica Ruiz Y, Pilhatsch M, Pinna M, da Ponte FDR, Quiroz D, Ramesar R, Rasgon N, Reddy MS, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Scippa ÂM, Severus E, Simhandl C, Stein DJ, Strejilevich S, Subramaniam M, Sulaiman AH, Suominen K, Tagata H, Tatebayashi Y, Tondo L, Torrent C, Vaaler AE, Veeh J, Vieta E, Viswanath B, Yoldi-Negrete M, Zetin M, Zgueb Y, Whybrow PC

Solar insolation in springtime influences age of onset of bipolar I disorder.

Acta Psychiatr Scand 2017 Dec;136(6):571-582. Epub 2017 jul 19

PMID: 28722128

Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, Adolfsson R, Air TM, Akil H, Alda M, Alliey-Rodriguez N, Andreassen OA, Babadjanova G, Bass NJ, Bauer M, Baune BT, Bellivier F, Bergen S, Bethell A, Biernacka JM, Blackwood DHR, Boks MP, Boomsma DI, Børglum AD, Borrmann-Hassenbach M, Brennan P, Budde M, Buttenschøn HN, Byrne EM, Cervantes P, Clarke TK, Craddock N, Cruceanu C, Curtis D, Czerski PM, Dannlowski U, Davis T, de Geus EJC, Di Florio A, Djurovic S, Domenici E, Edenberg HJ, Etain B, Fischer SB, Forty L, Fraser C, Frye MA, Fullerton JM, Gade K, Gershon ES, Giegling I, Gordon SD, Gordon-Smith K, Grabe HJ, Green EK, Greenwood TA, Grigoroiu-Serbanescu M, Guzman-Parra J, Hall LS, Hamshere M, Hauser J, Hautzinger M, Heilbronner U, Herms S, Hitturlingappa S, Hoffmann P, Holmans P, Hottenga JJ, Jamain S, Jones I, Jones LA, Juréus A, Kahn RS, Kammerer-Ciernioch J, Kirov G, Kittel-Schneider S, Kloiber S, Knott SV, Kogevinas M, Landén M, Leber M, Leboyer M, Li QS, Lissowska J, Lucae S, Martin NG, Mayoral-Cleries F, McElroy SL, McIntosh AM, McKay JD, McQuillin A, Medland SE, Middeldorp CM, Milaneschi Y, Mitchell PB, Montgomery GW, Morken G, Mors O, Mühleisen TW, Müller-Myhsok B, Myers RM, Nievergelt CM, Nurnberger JI, O'Donovan MC, Loohuis LMO, Ophoff R, Oruc L, Owen MJ, Paciga SA, Penninx BWJH, Perry A, Pfennig A, Potash JB, Preisig M, Reif A, Rivas F, Rouleau GA, Schofield PR, Schulze TG, Schwarz M, Scott L, Sinnamon GCB, Stahl EA, Strauss J, Turecki G, Van der Auwera S, Vedder H, Vincent JB, Willemsen G, Witt CC, Wray NR, Xi HS, , , , Tadic A, Dahmen N, Schott BH, Cichon S, Nöthen MM, Ripke S, Mobascher A, Rujescu D, Lieb K, Roepke S, Schmahl C, Bohus M, Rietschel M

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

Transl Psychiatry 2017 Jun 20;7(6):e1155. Epub 2017 jun 20

PMID: 28632202

Scott J, Vaaler AE, Fasmer OB, Morken G, Krane-Gartiser K

A pilot study to determine whether combinations of objectively measured activity parameters can be used to differentiate between mixed states, mania, and bipolar depression.

Int J Bipolar Disord 2017 Dec;5(1):5. Epub 2017 mar 1

PMID: 28155205

Scott J, Murray G, Henry C, Morken G, Scott E, Angst J, Merikangas KR, Hickie IB

Activation in Bipolar Disorders: A Systematic Review.

JAMA Psychiatry 2017 Feb 01;74(2):189-196.

PMID: 28002572

Haug E, Øie M, Andreassen OA, Bratlien U, Nelson B, Melle I, Møller P

High levels of anomalous self-experience are associated with longer duration of untreated psychosis.

Early Interv Psychiatry 2017 04;11(2):133-138. Epub 2015 jan 15

PMID: 25589153

Sæther SG, Schou M, Stoecker W, Teegen B, Borowski K, Vaaler A, Kondziella D, Reitan SK

Onconeural Antibodies in Acute Psychiatric Inpatient Care.

J Neuropsychiatry Clin Neurosci 2017 Winter;29(1):74-76. Epub 2016 aug 31

PMID: 27578448

Smeland OB, Frei O, Kauppi K, Hill WD, Li W, Wang Y, Krull F, Bettella F, Eriksen JA, Witoelar A, Davies G, Fan CC, Thompson WK, Lam M, Lencz T, Chen CH, Ueland T, Jönsson EG, Djurovic S, Deary IJ, Dale AM, Andreassen OA,

Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function.

JAMA Psychiatry 2017 Oct 01;74(10):1065-1075.

PMID: 28746715

Smeland OB, Wang Y, Frei O, Li W, Hibar DP, Franke B, Bettella F, Witoelar A, Djurovic S, Chen CH, Thompson PM, Dale AM, Andreassen OA

Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms.

Schizophr Bull 2018 06 06;44(4):854-864.

PMID: 29136250

Smeland OB, Wang Y, Lo MT, Li W, Frei O, Witoelar A, Tesli M, Hinds DA, Tung JY, Djurovic S, Chen CH, Dale AM, Andreassen OA

Identification of genetic loci shared between schizophrenia and the Big Five personality traits.

Sci Rep 2017 May 22;7(1):2222. Epub 2017 mai 22

PMID: 28533504

Le Hellard S, Wang Y, Witoelar A, Zuber V, Bettella F, Hugdahl K, Espeseth T, Steen VM, Melle I, Desikan R, Schork AJ, Thompson WK, Dale AM, Djurovic S, Andreassen OA,

Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment.

Schizophr Bull 2017 05 01;43(3):654-664.

PMID: 27338279

Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, Smeland OB, Schork A, Holland D, Kauppi K, Sanyal N, Escott-Price V, Smith DJ, O'Donovan M, Stefansson H, Bjornsdottir G, Thorgeirsson TE, Stefansson K, McEvoy LK, Dale AM, Andreassen OA, Chen CH

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders.

Nat Genet 2017 Jan;49(1):152-156. Epub 2016 des 5

PMID: 27918536

Aas M, Henry C, Bellivier F, Lajnef M, Gard S, Kahn JP, Lagerberg TV, Aminoff SR, Bjella T, Leboyer M, Andreassen OA, Melle I, Etain B

Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders.

Psychol Med 2017 Apr;47(5):902-912. Epub 2016 nov 29

PMID: 27894372

Østefjells T, Lystad JU, Berg AO, Hagen R, Loewy R, Sandvik L, Melle I, Røssberg JI

Metacognitive beliefs mediate the effect of emotional abuse on depressive and psychotic symptoms in severe mental disorders.

Psychol Med 2017 Oct;47(13):2323-2333. Epub 2017 apr 11

PMID: 28397634

Gardsjord ES, Romm KL, Røssberg JI, Friis S, Barder HE, Evensen J, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, Melle I

Is going into stable symptomatic remission associated with a more positive development of life satisfaction? A 10-year follow-up study of first episode psychosis.

Schizophr Res 2018 03;193():364-369. Epub 2017 jul 9

PMID: 28701275

Melle I, Olav Johannesen J, Haahr UH, ten Velden Hegelstad W, Joa I, Langeveld J, Larsen TK, Ilner Opjordsmoen S, Qin P, Ivar Røssberg J, Rishovd Rund B, Simonsen E, Vaglum PJW, McGlashan TH, Friis S

Causes and predictors of premature death in first-episode schizophrenia spectrum disorders.

World Psychiatry 2017 Jun;16(2):217-218.

PMID: 28498600

Smith RL, Haslemo T, Andreassen OA, Eliasson E, Dahl ML, Spigset O, Molden E

Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study.

CNS Drugs 2017 Nov;31(11):991-997.

PMID: 28948574

Hoseth EZ, Ueland T, Dieset I, Birnbaum R, Shin JH, Kleinman JE, Hyde TM, Mørch RH, Hope S, Lekva T, Abraityte AJ, Michelsen AE, Melle I, Westlye LT, Ueland T, Djurovic S, Aukrust P, Weinberger DR, Andreassen OA

A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue.

Schizophr Bull 2017 Jul 01;43(4):881-890.

PMID: 28049760

Aas M, Dieset I, Hope S, Hoseth E, Mørch R, Reponen E, Steen NE, Laskemoen JF, Ueland T, Aukrust P, Agartz I, Andreassen OA, Melle I

Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses.

Brain Behav Immun 2017 Oct;65():342-349. Epub 2017 jun 13

PMID: 28619247

Aas M, Kauppi K, Brandt CL, Tesli M, Kaufmann T, Steen NE, Agartz I, Westlye LT, Andreassen OA, Melle I

Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders.

Psychol Med 2017 Mar;47(4):669-679. Epub 2016 nov 11

PMID: 27834153

Church C, Andreassen OA, Lorentzen S, Melle I, Aas M

Childhood Trauma and Minimization/Denial in People with and without a Severe Mental Disorder.

Front Psychol 2017;8():1276. Epub 2017 aug 24

PMID: 28883800

Vaskinn A, Lagerberg TV, Bjella TD, Simonsen C, Andreassen OA, Ueland T, Sundet K

Impairment in emotion perception from body movements in individuals with bipolar I and bipolar II disorder is associated with functional capacity.

Int J Bipolar Disord 2017 Dec;5(1):13. Epub 2017 jun 21

PMID: 28332121

Demmo C, Lagerberg TV, Aminoff SR, Hellvin T, Kvitland LR, Simonsen C, Haatveit B, Andreassen OA, Melle I, Ueland T

Course of neurocognitive function in first treatment bipolar I disorder: One-year follow-up study.

Psychiatry Res 2017 Mar;249():286-292. Epub 2016 des 31

PMID: 28142102

Demmo C, Lagerberg TV, Kvitland LR, Aminoff SR, Hellvin T, Simonsen C, Haatveit B, Andreassen OA, Melle I, Ueland T

Neurocognitive functioning, clinical course and functional outcome in first-treatment bipolar I disorder patients with and without clinical relapse: A 1-year follow-up study.

Bipolar Disord 2018 05;20(3):228-237. Epub 2017 nov 9

PMID: 29121444

Engelstad KN, Sundet KS, Andreassen OA, Vaskinn A

Body language reading of emotion in schizophrenia: Associations with symptoms and functional outcome.

Scand J Psychol 2017 Oct;58(5):359-366. Epub 2017 aug 22

PMID: 28833180

Nerhus M, Berg AO, Simonsen C, Haram M, Haatveit B, Dahl SR, Gurholt TP, Bjella TD, Ueland T, Andreassen OA, Melle I

Vitamin D Deficiency Associated With Cognitive Functioning in Psychotic Disorders.

J Clin Psychiatry 2017 Jul;78(7):e750-e757.

PMID: 28493652

Østefjells T, Melle I, Aminoff SR, Hellvin T, Hagen R, Lagerberg TV, Lystad JU, Røssberg JI

An exploration of metacognitive beliefs and thought control strategies in bipolar disorder.

Compr Psychiatry 2017 Feb;73():84-92. Epub 2016 nov 23

PMID: 27918949

Simonsen C, Faerden A, Romm KL, Berg AO, Bjella T, Sundet K, Ueland T, Andreassen O, Melle I

Early clinical recovery in first-episode psychosis: Symptomatic remission and its correlates at 1-year follow-up.

Psychiatry Res 2017 Aug;254():118-125. Epub 2017 apr 24

PMID: 28460281

Fjukstad KK, Engum A, Lydersen S, Dieset I, Steen NE, Andreassen OA, Spigset O

Metabolic risk factors in schizophrenia and bipolar disorder: The effect of comedication with selective serotonin reuptake inhibitors and antipsychotics.

Eur Psychiatry 2018 02;48():71-78. Epub 2017 apr 17

PMID: 29331603

Gjerde PB, Dieset I, Simonsen C, Hoseth EZ, Iversen T, Lagerberg TV, Lyngstad SH, Mørch RH, Skrede S, Andreassen OA, Melle I, Steen VM

Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis.

Schizophr Res 2017 Nov 09. Epub 2017 nov 9

PMID: 29129510

Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Ueland T, Spigset O, Andreassen OA

Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders.

World J Biol Psychiatry 2017 Sep;18(6):471-482. Epub 2016 nov 15

PMID: 27712130

Mørch RH, Dieset I, Faerden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Haram M, Falk RS, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA

Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study.

Acta Psychiatr Scand 2017 10;136(4):400-408. Epub 2017 aug 16

PMID: 28815548

Lange EH, Nerland S, Jørgensen KN, Mørch-Johnsen L, Nesvåg R, Hartberg CB, Haukvik UK, Osnes K, Melle I, Andreassen OA, Agartz I

Alcohol use is associated with thinner cerebral cortex and larger ventricles in schizophrenia, bipolar disorder and healthy controls.

Psychol Med 2017 Mar;47(4):655-668. Epub 2016 nov 10

PMID: 27830632

Jørgensen KN, Nesvåg R, Nerland S, Mørch-Johnsen L, Westlye LT, Lange EH, Haukvik UK, Hartberg CB, Melle I, Andreassen OA, Agartz I

Brain volume change in first-episode psychosis: an effect of antipsychotic medication independent of BMI change.

Acta Psychiatr Scand 2017 Feb;135(2):117-126. Epub 2016 des 7

PMID: 27925164

Skåtun KC, Kaufmann T, Brandt CL, Doan NT, Alnæs D, Tønnesen S, Biele G, Vaskinn A, Melle I, Agartz I, Andreassen OA, Westlye LT

Thalamo-cortical functional connectivity in schizophrenia and bipolar disorder.

Brain Imaging Behav 2018 Jun;12(3):640-652.

PMID: 28444556

Andreassen OA

eHealth provides a novel opportunity to exploit the advantages of the Nordic countries in psychiatric genetic research, building on the public health care system, biobanks, and registries.

Am J Med Genet B Neuropsychiatr Genet 2017 Jul 07. Epub 2017 jul 7

PMID: 28686333

Andreassen OA

Diabetes and Schizophrenia-New Findings for an Old Puzzle.

Am J Psychiatry 2017 07 01;174(7):616-617.

PMID: 28669214

Quintana DS, Steen NE, Andreassen OA

The Promise of Intranasal Esketamine as a Novel and Effective Antidepressant.

JAMA Psychiatry 2017 Dec 27. Epub 2017 des 27

PMID: 29282452

Sallaup TV, Vaaler AE, Iversen VC, Guzey IC

Challenges in detecting and diagnosing substance use in women in the acute psychiatric department: a naturalistic cohort study.

BMC Psychiatry 2016 Nov 17;16(1):406. Epub 2016 nov 17

PMID: 27855664

Schou M, Sæther SG, Borowski K, Teegen B, Kondziella D, Stoecker W, Vaaler A, Reitan SK

Prevalence of serum anti-neuronal autoantibodies in patients admitted to acute psychiatric care.

Psychol Med 2016 Dec;46(16):3303-3313. Epub 2016 sep 9

PMID: 27609625

Krane-Gartiser K, Vaaler AE, Fasmer OB, Morken G

Distribution and Characteristics of Active and Inactive Periods Distinguish Unipolar Depression With and Without Motor Retardation.

J Clin Psychiatry 2016 Jun;77(6):841-2.

PMID: 27337419

Langsrud K, Vaaler AE, Kallestad H, Morken G

Sleep patterns as a predictor for length of stay in a psychiatric intensive care unit.

Psychiatry Res 2016 Mar 30;237():252-6. Epub 2016 jan 16

PMID: 26805566

De Deyne S, Elvevåg B, Hui CL, Poon VW, Chen EY

Rich semantic networks applied to schizophrenia: A new framework.

Schizophr Res 2016 Oct;176(2-3):454-5. Epub 2016 mai 28

PMID: 27245710

Elvevåg B, Cohen AS, Wolters MK, Whalley HC, Gountouna VE, Kuznetsova KA, Watson AR, Nicodemus KK

An examination of the language construct in NIMH's research domain criteria: Time for reconceptualization!

Am J Med Genet B Neuropsychiatr Genet 2016 Sep;171(6):904-19. Epub 2016 mar 10

PMID: 26968151

Foltz PW, Rosenstein M, Elvevåg B

Detecting clinically significant events through automated language analysis: Quo imus?

NPJ Schizophr 2016;2():15054. Epub 2016 jan 6

PMID: 27336051

Verheyen S, Voorspoels W, Longenecker J, Weinberger DR, Elvevåg B, Storms G

Invalid assumptions in clustering analyses of category fluency data: Reply to Sung, Gordon and Schretlen (2015).

Cortex 2016 Feb;75():255-9. Epub 2015 mai 21

PMID: 26059474

Altamura M, Elvevåg B, Goldberg TE, Carver FW, Weinberger DR, Coppola R

The impact of Val108/158Met polymorphism of catechol-O-methyltransferase on brain oscillations during working memory.

Neurosci Lett 2016 Jan 01;610():86-91. Epub 2015 nov 1

PMID: 26536074

Steinan MK, Morken G, Lagerberg TV, Melle I, Andreassen OA, Vaaler AE, Scott J

Delayed sleep phase: An important circadian subtype of sleep disturbance in bipolar disorders.

J Affect Disord 2016 Feb;191():156-63. Epub 2015 nov 24

PMID: 26655861

Torgersen T, Gjervan B, Lensing MB, Rasmussen K

Optimal management of ADHD in older adults.

Neuropsychiatr Dis Treat 2016;12():79-87. Epub 2016 jan 8

PMID: 26811680

Mørch RH, Dieset I, Færden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA

Inflammatory evidence for the psychosis continuum model.

Psychoneuroendocrinology 2016 May;67():189-97. Epub 2016 feb 17

PMID: 26923849

Oedegaard KJ, Alda M, Anand A, Andreassen OA, Balaraman Y, Berrettini WH, Bhattacharjee A, Brennand KJ, Burdick KE, Calabrese JR, Calkin CV, Claasen A, Coryell WH, Craig D, DeModena A, Frye M, Gage FH, Gao K, Garnham J, Gershon E, Jakobsen P, Leckband SG, McCarthy MJ, McInnis MG, Maihofer AX, Mertens J, Morken G, Nievergelt CM, Nurnberger J, Pham S, Schoeyen H, Shekhtman T, Shilling PD, Szelinger S, Tarwater B, Yao J, Zandi PP, Kelsoe JR

The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample.

BMC Psychiatry 2016 May 05;16():129. Epub 2016 mai 5

PMID: 27150464

Krane-Gartiser K, Steinan MK, Langsrud K, Vestvik V, Sand T, Fasmer OB, Kallestad H, Morken G

Mood and motor activity in euthymic bipolar disorder with sleep disturbance.

J Affect Disord 2016 Sep 15;202():23-31. Epub 2016 mai 24

PMID: 27253213

Kallestad H, Wullum E, Scott J, Stiles TC, Morken G

The long-term outcomes of an effectiveness trial of group versus individual psychoeducation for bipolar disorders.

J Affect Disord 2016 Sep 15;202():32-8. Epub 2016 mai 24

PMID: 27253214

Steinan MK, Scott J, Lagerberg TV, Melle I, Andreassen OA, Vaaler AE, Morken G

Sleep problems in bipolar disorders: more than just insomnia.

Acta Psychiatr Scand 2016 May;133(5):368-77. Epub 2015 nov 21

PMID: 26590799

Fasmer OB, Hauge E, Berle JØ, Dilsaver S, Oedegaard KJ

Distribution of Active and Resting Periods in the Motor Activity of Patients with Depression and Schizophrenia.

Psychiatry Investig 2016 Jan;13(1):112-20. Epub 2015 okt 13

PMID: 26766953

Fuglseth NL, Gjestad R, Mellesdal L, Hunskaar S, Oedegaard KJ, Johansen IH

Factors associated with disallowance of compulsory mental healthcare referrals.

Acta Psychiatr Scand 2016 May;133(5):410-8. Epub 2016 jan 17

PMID: 26774865

Fasmer OB, Mjeldheim K, Førland W, Hansen AL, Syrstad VE, Oedegaard KJ, Berle JØ

Linear and non-linear analyses of Conner's Continuous Performance Test-II discriminate adult patients with attention deficit hyperactivity disorder from patients with mood and anxiety disorders.

BMC Psychiatry 2016 Aug 11;16(1):284. Epub 2016 aug 11

PMID: 27515830

Oedegaard CH, Berk L, Berk M, , Youngstrom EA, Dilsaver SC, Belmaker RH, Oedegaard KJ, Fasmer OB, Engebretsen IM

An ISBD perspective on the sociocultural challenges of managing bipolar disorder: A content analysis.

Aust N Z J Psychiatry 2016 Nov;50(11):1096-1103. Epub 2016 okt 14

PMID: 27742913

Helle S, Ringen PA, Melle I, Larsen TK, Gjestad R, Johnsen E, Lagerberg TV, Andreassen OA, Kroken RA, Joa I, ten Velden Hegelstad W, Løberg EM

Cannabis use is associated with 3years earlier onset of schizophrenia spectrum disorder in a naturalistic, multi-site sample (N=1119).

Schizophr Res 2016 Jan;170(1):217-21. Epub 2015 des 9

PMID: 26682958

Aas M, Henry C, Andreassen OA, Bellivier F, Melle I, Etain B

The role of childhood trauma in bipolar disorders.

Int J Bipolar Disord 2016 Dec;4(1):2. Epub 2016 jan 13

PMID: 26763504

Wang Y, Thompson WK, Schork AJ, Holland D, Chen CH, Bettella F, Desikan RS, Li W, Witoelar A, Zuber V, Devor A, , , Nöthen MM, Rietschel M, Chen Q, Werge T, Cichon S, Weinberger DR, Djurovic S, O'Donovan M, Visscher PM, Andreassen OA, Dale AM

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS.

PLoS Genet 2016 Jan;12(1):e1005803. Epub 2016 jan 25

PMID: 26808560

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE, , Daly MJ, Carroll MC, Stevens B, McCarroll SA

Schizophrenia risk from complex variation of complement component 4.

Nature 2016 Feb 11;530(7589):177-83. Epub 2016 jan 27

PMID: 26814963

Demmo C, Lagerberg TV, Aminoff SR, Hellvin T, Kvitland LR, Simonsen C, Andreassen OA, Melle I, Ueland T

History of psychosis and previous episodes as potential explanatory factors for neurocognitive impairment in first-treatment bipolar I disorder.

Bipolar Disord 2016 Mar;18(2):136-47. Epub 2016 mar 18

PMID: 26990158

Fountoulakis KN, Chatzikosta I, Pastiadis K, Zanis P, Kawohl W, Kerkhof AJ, Navickas A, Höschl C, Lecic-Tosevski D, Sorel E, Rancans E, Palova E, Juckel G, Isacsson G, Jagodic HK, Botezat-Antonescu I, Rybakowski J, Azorin JM, Cookson J, Waddington J, Pregelj P, Demyttenaere K, Hranov LG, Stevovic LI, Pezawas L, Adida M, Figuera ML, Jakovljevic M, Vichi M, Perugi G, Andreassen OA, Vukovic O, Mavrogiorgou P, Varnik P, Dome P, Winkler P, Salokangas RK, From T, Danileviciute V, Gonda X, Rihmer Z, Forsman J, Grady A, Hyphantis T, Dieset I, Soendergaard S, Pompili M, Bech P

Relationship of suicide rates with climate and economic variables in Europe during 2000-2012.

Ann Gen Psychiatry 2016;15():19. Epub 2016 aug 9

PMID: 27508001

Peng Q, Schork A, Bartsch H, Lo MT, Panizzon MS, , , Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Dale AM, Schork NJ, Chen CH

Conservation of Distinct Genetically-Mediated Human Cortical Pattern.

PLoS Genet 2016 Jul;12(7):e1006143. Epub 2016 jul 26

PMID: 27459196

Fjukstad KK, Engum A, Lydersen S, Dieset I, Steen NE, Andreassen OA, Spigset O

Metabolic Abnormalities Related to Treatment With Selective Serotonin Reuptake Inhibitors in Patients With Schizophrenia or Bipolar Disorder.

J Clin Psychopharmacol 2016 Dec;36(6):615-620.

PMID: 27749681

Haug E, Øie MG, Andreassen OA, Bratlien U, Romm KL, Møller P, Melle I

The Association between Anomalous Self-experiences, Self-esteem and Depressive Symptoms in First Episode Schizophrenia.

Front Hum Neurosci 2016;10():557. Epub 2016 nov 7

PMID: 27872587

Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Vaskinn A, Spigset O, Andreassen OA

Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting.

Int J Bipolar Disord 2016 Dec;4(1):24. Epub 2016 des 9

PMID: 27858347

Kvitland LR, Ringen PA, Aminoff SR, Demmo C, Hellvin T, Lagerberg TV, Andreassen OA, Melle I

Duration of untreated illness in first-treatment bipolar I disorder in relation to clinical outcome and cannabis use.

Psychiatry Res 2016 Dec 30;246():762-768. Epub 2016 okt 28

PMID: 27814886

Ringen PA, Nesvåg R, Helle S, Lagerberg TV, Lange EH, Løberg EM, Agartz I, Andreassen OA, Melle I

Premorbid cannabis use is associated with more symptoms and poorer functioning in schizophrenia spectrum disorder.

Psychol Med 2016 Nov;46(15):3127-3136. Epub 2016 aug 18

PMID: 27534999

Nerhus M, Berg AO, Kvitland LR, Dieset I, Hope S, Dahl SR, Weibell MA, Romm KL, Faerden A, Andreassen OA, Melle I

Low vitamin D is associated with negative and depressive symptoms in psychotic disorders.

Schizophr Res 2016 Dec;178(1-3):44-49. Epub 2016 aug 29

PMID: 27595553

Solberg DK, Bentsen H, Refsum H, Andreassen OA

Lipid profiles in schizophrenia associated with clinical traits: a five year follow-up study.

BMC Psychiatry 2016 Aug 25;16():299. Epub 2016 aug 25

PMID: 27562545

Ormstad H, Dahl J, Verkerk R, Andreassen OA, Maes M

Increased plasma levels of competing amino acids, rather than lowered plasma tryptophan levels, are associated with a non-response to treatment in major depression.

Eur Neuropsychopharmacol 2016 Aug;26(8):1286-96. Epub 2016 mai 26

PMID: 27237997

Dahl J, Ormstad H, Aass HC, Sandvik L, Malt UF, Andreassen OA

Recovery from major depressive disorder episode after non-pharmacological treatment is associated with normalized cytokine levels.

Acta Psychiatr Scand 2016 Jul;134(1):40-7. Epub 2016 mar 30

PMID: 27028967

Tesli M, Wirgenes KV, Hughes T, Bettella F, Athanasiu L, Hoseth ES, Nerhus M, Lagerberg TV, Steen NE, Agartz I, Melle I, Dieset I, Djurovic S, Andreassen OA

VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls.

Br J Psychiatry 2016 Aug;209(2):114-20. Epub 2016 mar 3

PMID: 26941264

Holland D, Wang Y, Thompson WK, Schork A, Chen CH, Lo MT, Witoelar A, , , Werge T, O'Donovan M, Andreassen OA, Dale AM

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics.

Front Genet 2016;7():15. Epub 2016 feb 16

PMID: 26909100

Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Yao Y, Ho YY, Martin NG, Wright MJ, , , , , O'Donovan MC, Thompson PM, Neale BM, Medland SE, Sullivan PF

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.

Nat Neurosci 2016 Mar;19(3):420-31. Epub 2016 feb 1

PMID: 26854805

Olsen RE, Kroken RA, Bjørhovde S, Aanesen K, Jørgensen HA, Løberg EM, Johnsen E

Influence of different second generation antipsychotics on the QTc interval: A pragmatic study.

World J Psychiatry 2016 Dec 22;6(4):442-448. Epub 2016 des 22

PMID: 28078208

Anda L, Brønnick KS, Johnsen E, Kroken RA, Jørgensen H, Løberg EM

The Course of Neurocognitive Changes in Acute Psychosis: Relation to Symptomatic Improvement.

PLoS One 2016;11(12):e0167390. Epub 2016 des 15

PMID: 27977720

Johnsen E, Fathian F, Kroken RA, Steen VM, Jørgensen HA, Gjestad R, Løberg EM

The serum level of C-reactive protein (CRP) is associated with cognitive performance in acute phase psychosis.

BMC Psychiatry 2016 Mar 14;16():60. Epub 2016 mar 14

PMID: 26973142

Bø B, Ottesen ØH, Gjestad R, Jørgensen HA, Kroken RA, Løberg EM, Johnsen E

Patient satisfaction after acute admission for psychosis.

Nord J Psychiatry 2016 Jul;70(5):321-8. Epub 2016 jan 11

PMID: 26750532

Bjornestad J, Joa I, Larsen TK, Langeveld J, Davidson L, ten Velden Hegelstad W, Anda LG, Veseth M, Melle I, Johannessen JO, Bronnick K

"Everyone Needs a Friend Sometimes" - Social Predictors of Long-Term Remission In First Episode Psychosis.

Front Psychol 2016;7():1491. Epub 2016 okt 4

PMID: 27757090

Solesvik M, Joa I, Larsen TK, Langeveld J, Johannessen JO, Bjørnestad J, Anda LG, Gisselgård J, Hegelstad WT, Brønnick K

Visual Hallucinations in First-Episode Psychosis: Association with Childhood Trauma.

PLoS One 2016;11(5):e0153458. Epub 2016 mai 4

PMID: 27144681

Gardsjord ES, Romm KL, Friis S, Barder HE, Evensen J, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, Melle I, Røssberg JI

Subjective quality of life in first-episode psychosis. A ten year follow-up study.

Schizophr Res 2016 Apr;172(1-3):23-8. Epub 2016 mar 2

PMID: 26947210

Haahr UH, Larsen TK, Simonsen E, Rund BR, Joa I, Rossberg JI, Johannessen JO, Langeveld J, Evensen J, Trauelsen AM, Vaglum P, Opjordsmoen S, Hegelstad WT, Friis S, McGlashan T, Melle I

Relation between premorbid adjustment, duration of untreated psychosis and close interpersonal trauma in first-episode psychosis.

Early Interv Psychiatry 2016 Jan 23. Epub 2016 jan 23

PMID: 26800653

Friis S, Melle I, Johannessen JO, Røssberg JI, Barder HE, Evensen JH, Haahr U, ten Velden Hegelstad W, Joa I, Langeveld J, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum PW, McGlashan TH

Early Predictors of Ten-Year Course in First-Episode Psychosis.

Psychiatr Serv 2016 Apr 01;67(4):438-43. Epub 2015 nov 16

PMID: 26567932

Rund BR, Barder HE, Evensen J, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Melle I, Opjordsmoen S, Røssberg JI, Simonsen E, Sundet K, Vaglum P, McGlashan T, Friis S

Neurocognition and Duration of Psychosis: A 10-year Follow-up of First-Episode Patients.

Schizophr Bull 2016 Jan;42(1):87-95. Epub 2015 jun 21

PMID: 26101305

Sönmez N, Røssberg JI, Evensen J, Barder HE, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld H, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, Friis S

Depressive symptoms in first-episode psychosis: a 10-year follow-up study.

Early Interv Psychiatry 2016 Jun;10(3):227-33. Epub 2014 jun 23

PMID: 24956976

Bay N, Bjørnestad J, Johannessen JO, Larsen TK, Joa I

Obstacles to care in first-episode psychosis patients with a long duration of untreated psychosis.

Early Interv Psychiatry 2016 Feb;10(1):71-6. Epub 2014 mai 27

PMID: 24861169

Kvitland LR, Melle I, Aminoff SR, Demmo C, Lagerberg TV, Andreassen OA, Ringen PA

Continued cannabis use at one year follow up is associated with elevated mood and lower global functioning in bipolar I disorder.

BMC Psychiatry 2015;15():11. Epub 2015 feb 5

PMID: 25651990

Andreassen OA, Harbo HF, Wang Y, Thompson WK, Schork AJ, Mattingsdal M, Zuber V, Bettella F, Ripke S, Kelsoe JR, Kendler KS, O'Donovan MC, Sklar P, , , McEvoy LK, Desikan RS, Lie BA, Djurovic S, Dale AM

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci.

Mol Psychiatry 2015 Feb;20(2):207-14. Epub 2014 jan 28

PMID: 24468824

Mellerup E, Andreassen OA, Bennike B, Dam H, Djurovic S, Hansen T, Jorgensen MB, Kessing LV, Koefoed P, Melle I, Mors O, Werge T, Moeller GL

Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons.

PLoS One 2015;10(11):e0143432. Epub 2015 nov 20

PMID: 26587987

Grellmann C, Bitzer S, Neumann J, Westlye LT, Andreassen OA, Villringer A, Horstmann A

Comparison of variants of canonical correlation analysis and partial least squares for combined analysis of MRI and genetic data.

Neuroimage 2015 Feb 15;107():289-310. Epub 2014 des 17

PMID: 25527238

Hoeffding LK, Duong LT, Ingason A, Rosengren A, Sorbanski E, Witt SH, Djurovic S, Andreassen OA, Hansen T, Werge T, Rasmussen HB

Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders.

Nord J Psychiatry 2016;70(4):276-9. Epub 2015 nov 11

PMID: 26559242

Zayats T, Athanasiu L, Sonderby I, Djurovic S, Westlye LT, Tamnes CK, Fladby T, Aase H, Zeiner P, Reichborn-Kjennerud T, Knappskog PM, Knudsen GP, Andreassen OA, Johansson S, Haavik J

Genome-wide analysis of attention deficit hyperactivity disorder in Norway.

PLoS One 2015;10(4):e0122501. Epub 2015 apr 13

PMID: 25875332

Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, Mcgrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR, , , Byerley W, Cahn W, Cantor RM, Cichon S, Cormican P, Curtis D, Djurovic S, Escott-Price V, Gejman PV, Georgieva L, Giegling I, Hansen TF, Ingason A, Kim Y, Konte B, Lee PH, McIntosh A, McQuillin A, Morris DW, Nöthen MM, O'Dushlaine C, Olincy A, Olsen L, Pato CN, Pato MT, Pickard BS, Posthuma D, Rasmussen HB, Rietschel M, Rujescu D, Schulze TG, Silverman JM, Thirumalai S, Werge T, , Agartz I, Amin F, Azevedo MH, Bass N, Black DW, Blackwood DH, Bruggeman R, Buccola NG, Choudhury K, Cloninger RC, Corvin A, Craddock N, Daly MJ, Datta S, Donohoe GJ, Duan J, Dudbridge F, Fanous A, Freedman R, Freimer NB, Friedl M, Gill M, Gurling H, De Haan L, Hamshere ML, Hartmann AM, Holmans PA, Kahn RS, Keller MC, Kenny E, Kirov GK, Krabbendam L, Krasucki R, Lawrence J, Lencz T, Levinson DF, Lieberman JA, Lin DY, Linszen DH, Magnusson PK, Maier W, Malhotra AK, Mattheisen M, Mattingsdal M, McCarroll SA, Medeiros H, Melle I, Milanova V, Myin-Germeys I, Neale BM, Ophoff RA, Owen MJ, Pimm J, Purcell SM, Puri V, Quested DJ, Rossin L, Ruderfer D, Sanders AR, Shi J, Sklar P, St Clair D, Scott Stroup T, van Os J, Visscher PM, Wiersma D, Zammit S, , Louis Bridges S, Choi HK, Coenen MJ, de Vries N, Dieud P, Greenberg JD, Huizinga TW, Padyukov L, Siminovitch KA, Tak PP, Worthington J, , De Jager PL, Denny JC, Gregersen PK, Klareskog L, Mariette X, Plenge RM, van Laar M, van Riel P

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.

Int J Epidemiol 2015 Aug 18. Epub 2015 aug 18

PMID: 26286434

Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Chakravarty MM, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O, Guadalupe T, Hass J, Woldehawariat G, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kim S, Klein M, Kraemer B, Lee PH, Olde Loohuis LM, Luciano M, Macare C, Mather KA, Mattheisen M, Milaneschi Y, Nho K, Papmeyer M, Ramasamy A, Risacher SL, Roiz-Santiañez R, Rose EJ, Salami A, Sämann PG, Schmaal L, Schork AJ, Shin J, Strike LT, Teumer A, van Donkelaar MM, van Eijk KR, Walters RK, Westlye LT, Whelan CD, Winkler AM, Zwiers MP, Alhusaini S, Athanasiu L, Ehrlich S, Hakobjan MM, Hartberg CB, Haukvik UK, Heister AJ, Hoehn D, Kasperaviciute D, Liewald DC, Lopez LM, Makkinje RR, Matarin M, Naber MA, McKay DR, Needham M, Nugent AC, Pütz B, Royle NA, Shen L, Sprooten E, Trabzuni D, van der Marel SS, van Hulzen KJ, Walton E, Wolf C, Almasy L, Ames D, Arepalli S, Assareh AA, Bastin ME, Brodaty H, Bulayeva KB, Carless MA, Cichon S, Corvin A, Curran JE, Czisch M, de Zubicaray GI, Dillman A, Duggirala R, Dyer TD, Erk S, Fedko IO, Ferrucci L, Foroud TM, Fox PT, Fukunaga M, Gibbs JR, Göring HH, Green RC, Guelfi S, Hansell NK, Hartman CA, Hegenscheid K, Heinz A, Hernandez DG, Heslenfeld DJ, Hoekstra PJ, Holsboer F, Homuth G, Hottenga JJ, Ikeda M, Jack CR, Jenkinson M, Johnson R, Kanai R, Keil M, Kent JW, Kochunov P, Kwok JB, Lawrie SM, Liu X, Longo DL, McMahon KL, Meisenzahl E, Melle I, Mohnke S, Montgomery GW, Mostert JC, Mühleisen TW, Nalls MA, Nichols TE, Nilsson LG, Nöthen MM, Ohi K, Olvera RL, Perez-Iglesias R, Pike GB, Potkin SG, Reinvang I, Reppermund S, Rietschel M, Romanczuk-Seiferth N, Rosen GD, Rujescu D, Schnell K, Schofield PR, Smith C, Steen VM, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Turner JA, Valdés Hernández MC, van 't Ent D, van der Brug M, van der Wee NJ, van Tol MJ, Veltman DJ, Wassink TH, Westman E, Zielke RH, Zonderman AB, Ashbrook DG, Hager R, Lu L, McMahon FJ, Morris DW, Williams RW, Brunner HG, Buckner RL, Buitelaar JK, Cahn W, Calhoun VD, Cavalleri GL, Crespo-Facorro B, Dale AM, Davies GE, Delanty N, Depondt C, Djurovic S, Drevets WC, Espeseth T, Gollub RL, Ho BC, Hoffmann W, Hosten N, Kahn RS, Le Hellard S, Meyer-Lindenberg A, Müller-Myhsok B, Nauck M, Nyberg L, Pandolfo M, Penninx BW, Roffman JL, Sisodiya SM, Smoller JW, van Bokhoven H, van Haren NE, Völzke H, Walter H, Weiner MW, Wen W, White T, Agartz I, Andreassen OA, Blangero J, Boomsma DI, Brouwer RM, Cannon DM, Cookson MR, De Geus EJ, Deary IJ, Donohoe G, Fernández G, Fisher SE, Francks C, Glahn DC, Grabe HJ, Gruber O, Hardy J, Hashimoto R, Hulshoff Pol HE, Jönsson EG, Kloszewska I, Lovestone S, Mattay VS, Mecocci P, McDonald C, McIntosh AM, Ophoff RA, Paus T, Pausova Z, Ryten M, Sachdev PS, Saykin AJ, Simmons A, Singleton A, Soininen H, Wardlaw JM, Weale ME, Weinberger DR, Adams HH, Launer LJ, Seiler S, Schmidt R, Chauhan G, Satizabal CL, Becker JT, Yanek L, van der Lee SJ, Ebling M, Fischl B, Longstreth WT, Greve D, Schmidt H, Nyquist P, Vinke LN, van Duijn Cm, Xue L, Mazoyer B, Bis JC, Gudnason V, Seshadri S, Ikram MA, , , , , , Martin NG, Wright MJ, Schumann G, Franke B, Thompson PM, Medland SE

Common genetic variants influence human subcortical brain structures.

Nature 2015 Apr 9;520(7546):224-9. Epub 2015 jan 21

PMID: 25607358

Chen CH, Peng Q, Schork AJ, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ, , , Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Schork N, Dale AM, ,

Large-scale genomics unveil polygenic architecture of human cortical surface area.

Nat Commun 2015;6():7549. Epub 2015 jul 20

PMID: 26189703

Goulart LF, Bettella F, Sønderby IE, Schork AJ, Thompson WK, Mattingsdal M, Steen VM, Zuber V, Wang Y, Dale AM, , Andreassen OA, Djurovic S

MicroRNAs enrichment in GWAS of complex human phenotypes.

BMC Genomics 2015;16():304. Epub 2015 apr 16

PMID: 25884492

Trampush JW, Lencz T, Knowles E, Davies G, Guha S, Pe'er I, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Ikeda M, Roussos P, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Scult M, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri A, Weinberger DR, Pendleton N, Iwata N, Darvasi A, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment.

Am J Med Genet B Neuropsychiatr Genet 2015 Jul;168B(5):363-73. Epub 2015 mai 7

PMID: 25951819

Howrigan DP, Simonson MA, Davies G, Harris SE, Tenesa A, Starr JM, Liewald DC, Deary IJ, McRae A, Wright MJ, Montgomery GW, Hansell N, Martin NG, Payton A, Horan M, Ollier WE, Abdellaoui A, Boomsma DI, DeRosse P, Knowles EE, Glahn DC, Djurovic S, Melle I, Andreassen OA, Christoforou A, Steen VM, Hellard SL, Sundet K, Reinvang I, Espeseth T, Lundervold AJ, Giegling I, Konte B, Hartmann AM, Rujescu D, Roussos P, Giakoumaki S, Burdick KE, Bitsios P, Donohoe G, Corley RP, Visscher PM, Pendleton N, Malhotra AK, Neale BM, Lencz T, Keller MC

Genome-wide autozygosity is associated with lower general cognitive ability.

Mol Psychiatry 2015 Sep 22. Epub 2015 sep 22

PMID: 26390830

Haram M, Tesli M, Bettella F, Djurovic S, Andreassen OA, Melle I

Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders.

Front Hum Neurosci 2015;9():9. Epub 2015 jan 23

PMID: 25667571

Zai CC, Manchia M, Sønderby IE, Yilmaz Z, De Luca V, Tiwari AK, Squassina A, Zai GC, Shaikh SA, Strauss J, King N, Le Foll B, Kaplan AS, Finseth PI, Vaaler AE, Djurovic S, Andreassen OA, Vincent JB, Kennedy JL

Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders.

World J Biol Psychiatry 2015 Apr;16(3):171-9. Epub 2014 sep 29

PMID: 25264289

Aminoff SR, Tesli M, Bettella F, Aas M, Lagerberg TV, Djurovic S, Andreassen OA, Melle I

Polygenic risk scores in bipolar disorder subgroups.

J Affect Disord 2015 Sep 1;183():310-4. Epub 2015 mai 22

PMID: 26047958

Athanasiu L, Smorr LL, Tesli M, Røssberg JI, Sønderby IE, Spigset O, Djurovic S, Andreassen OA

Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.

J Psychopharmacol 2015 Aug;29(8):884-91. Epub 2015 mai 5

PMID: 25944848

Kauppi K, Westlye LT, Tesli M, Bettella F, Brandt CL, Mattingsdal M, Ueland T, Espeseth T, Agartz I, Melle I, Djurovic S, Andreassen OA

Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls.

Schizophr Bull 2015 May;41(3):736-43. Epub 2014 nov 11

PMID: 25392519

Tesli M, Kauppi K, Bettella F, Brandt CL, Kaufmann T, Espeseth T, Mattingsdal M, Agartz I, Melle I, Djurovic S, Westlye LT, Andreassen OA

Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder.

PLoS One 2015;10(7):e0134202. Epub 2015 jul 29

PMID: 26222050

van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, De Haan L, Veltman DJ, Satterthwaite TD, Wolf DH, Gur RC, Gur RE, Potkin SG, Mathalon DH, Mueller BA, Preda A, Macciardi F, Ehrlich S, Walton E, Hass J, Calhoun VD, Bockholt HJ, Sponheim SR, Shoemaker JM, van Haren NE, Pol HE, Ophoff RA, Kahn RS, Roiz-Santiañez R, Crespo-Facorro B, Wang L, Alpert KI, Jönsson EG, Dimitrova R, Bois C, Whalley HC, McIntosh AM, Lawrie SM, Hashimoto R, Thompson PM, Turner JA

Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium.

Mol Psychiatry 2016 Apr;21(4):585. Epub 2015 aug 18

PMID: 26283641

van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, De Haan L, Veltman DJ, Satterthwaite TD, Wolf DH, Gur RC, Gur RE, Potkin SG, Mathalon DH, Mueller BA, Preda A, Macciardi F, Ehrlich S, Walton E, Hass J, Calhoun VD, Bockholt HJ, Sponheim SR, Shoemaker JM, van Haren NE, Pol HE, Ophoff RA, Kahn RS, Roiz-Santiañez R, Crespo-Facorro B, Wang L, Alpert KI, Jönsson EG, Dimitrova R, Bois C, Whalley HC, McIntosh AM, Lawrie SM, Hashimoto R, Thompson PM, Turner JA

Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium.

Mol Psychiatry 2015 Jun 2. Epub 2015 jun 2

PMID: 26033243

Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Baethge C, Bauer R, Baune BT, Bellivier F, Belmaker RH, Berk M, Bjella TD, Bossini L, Bersudsky Y, Wo Cheung EY, Conell J, Del Zompo M, Dodd S, Etain B, Fagiolini A, Frye MA, Fountoulakis KN, Garneau-Fournier J, Gonzalez-Pinto A, Gottlieb JF, Harima H, Hassel S, Henry C, Iacovides A, Isometsä ET, Kapczinski F, Kliwicki S, König B, Krogh R, Kunz M, Lafer B, Larsen ER, Lewitzka U, Lopez-Jaramillo C, MacQueen G, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I, Monteith S, Morken G, Munoz R, Nery FG, O'Donovan C, Osher Y, Pfennig A, Quiroz D, Ramesar R, Rasgon N, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Miranda-Scippa Â, Severus E, Simhandl C, Stein DJ, Strejilevich S, Sulaiman AH, Suominen K, Tagata H, Tatebayashi Y, Torrent C, Vieta E, Viswanath B, Wanchoo MJ, Zetin M, Whybrow PC

Influence of light exposure during early life on the age of onset of bipolar disorder.

J Psychiatr Res 2015 May;64():1-8. Epub 2015 mar 27

PMID: 25862378

Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Baethge C, Bauer R, Bellivier F, Belmaker RH, Berk M, Bjella TD, Bossini L, Bersudsky Y, Cheung EY, Conell J, Del Zompo M, Dodd S, Etain B, Fagiolini A, Frye MA, Fountoulakis KN, Garneau-Fournier J, Gonzalez-Pinto A, Harima H, Hassel S, Henry C, Iacovides A, Isometsä ET, Kapczinski F, Kliwicki S, König B, Krogh R, Kunz M, Lafer B, Larsen ER, Lewitzka U, Lopez-Jaramillo C, MacQueen G, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I, Monteith S, Morken G, Munoz R, Nery FG, O'Donovan C, Osher Y, Pfennig A, Quiroz D, Ramesar R, Rasgon N, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Scippa AM, Severus E, Simhandl C, Stein DJ, Strejilevich S, Hatim Sulaiman A, Suominen K, Tagata H, Tatebayashi Y, Torrent C, Vieta E, Viswanath B, Wanchoo MJ, Zetin M, Whybrow PC

Influence of birth cohort on age of onset cluster analysis in bipolar I disorder.

Eur Psychiatry 2015 Jan;30(1):99-105. Epub 2014 des 12

PMID: 25498240

Hope S, Hoseth E, Dieset I, Mørch RH, Aas M, Aukrust P, Djurovic S, Melle I, Ueland T, Agartz I, Ueland T, Westlye LT, Andreassen OA

Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls.

Schizophr Res 2015 Jul;165(2-3):188-94. Epub 2015 mai 5

PMID: 25956633

Solberg DK, Bentsen H, Refsum H, Andreassen OA

Association between serum lipids and membrane fatty acids and clinical characteristics in patients with schizophrenia.

Acta Psychiatr Scand 2015 Oct;132(4):293-300. Epub 2015 jan 16

PMID: 25597473

Dahl J, Andreassen OA, Verkerk R, Malt UF, Sandvik L, Brundin L, Ormstad H

Ongoing episode of major depressive disorder is not associated with elevated plasma levels of kynurenine pathway markers.

Psychoneuroendocrinology 2015 Jun;56():12-22. Epub 2015 feb 25

PMID: 25770856

Dieset I, Haukvik UK, Melle I, Røssberg JI, Ueland T, Hope S, Dale AM, Djurovic S, Aukrust P, Agartz I, Andreassen OA

Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders.

Schizophr Res 2015 Feb;161(2-3):222-8. Epub 2014 nov 27

PMID: 25433965

Nerhus M, Berg AO, Dahl SR, Holvik K, Gardsjord ES, Weibell MA, Bjella TD, Andreassen OA, Melle I

Vitamin D status in psychotic disorder patients and healthy controls - The influence of ethnic background.

Psychiatry Res 2015 Dec 15;230(2):616-21. Epub 2015 okt 20

PMID: 26500071

Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Vaskinn A, Spigset O, Andreassen OA

Serum level of venlafaxine is associated with better memory in psychotic disorders.

Schizophr Res 2015 Dec;169(1-3):386-92. Epub 2015 okt 26

PMID: 26516101

Engh JA, Andersen E, Holmen Tl, Martinsen EW, Mordal J, Morken G, Egeland J

Effects of high-intensity aerobic exercise on psychotic symptoms and neurocognition in outpatients with schizophrenia: study protocol for a randomized controlled trial.

Trials 2015;16(1):557. Epub 2015 des 8

PMID: 26646670

Krane-Gartiser K, Henriksen TE, Vaaler AE, Fasmer OB, Morken G

Actigraphically assessed activity in unipolar depression: a comparison of inpatients with and without motor retardation.

J Clin Psychiatry 2015 Sep;76(9):1181-7.

PMID: 26214574

Maier R, Moser G, Chen GB, Ripke S, , Coryell W, Potash JB, Scheftner WA, Shi J, Weissman MM, Hultman CM, Landén M, Levinson DF, Kendler KS, Smoller JW, Wray NR, Lee SH

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder.

Am J Hum Genet 2015 Feb 5;96(2):283-94. Epub 2015 jan 29

PMID: 25640677

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways.

Nat Neurosci 2015 Feb;18(2):199-209. Epub 2015 jan 19

PMID: 25599223

Schoeyen HK, Kessler U, Andreassen OA, Auestad BH, Bergsholm P, Malt UF, Morken G, Oedegaard KJ, Vaaler A

Treatment-resistant bipolar depression: a randomized controlled trial of electroconvulsive therapy versus algorithm-based pharmacological treatment.

Am J Psychiatry 2015 Jan;172(1):41-51. Epub 2014 okt 31

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Tidsskr Nor Laegeforen 2015 Feb 10;135(3):246-8. Epub 2015 feb 10

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Bramness JG, Walby FA, Morken G, Røislien J

Analyzing Seasonal Variations in Suicide With Fourier Poisson Time-Series Regression: A Registry-Based Study From Norway, 1969-2007.

Am J Epidemiol 2015 Aug 1;182(3):244-54. Epub 2015 jun 16

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Bratlien U, Øie M, Haug E, Møller P, Andreassen OA, Lien L, Melle I

Self-reported symptoms and health service use in adolescence in persons who later develop psychotic disorders: a prospective case-control study.

Early Interv Psychiatry 2015 Jun;9(3):221-7. Epub 2013 nov 14

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Haug E, Øie M, Andreassen OA, Bratlien U, Nelson B, Aas M, Møller P, Melle I

Anomalous self-experience and childhood trauma in first-episode schizophrenia.

Compr Psychiatry 2015 Jan;56():35-41. Epub 2014 okt 16

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Kjelby E, Sinkeviciute I, Gjestad R, Kroken RA, Løberg EM, Jørgensen HA, Hugdahl K, Johnsen E

Suicidality in schizophrenia spectrum disorders: the relationship to hallucinations and persecutory delusions.

Eur Psychiatry 2015 Oct;30(7):830-6. Epub 2015 sep 25

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Hugdahl K, Craven AR, Nygård M, Løberg EM, Berle JØ, Johnsen E, Kroken R, Specht K, Andreassen OA, Ersland L

Glutamate as a mediating transmitter for auditory hallucinations in schizophrenia: a (1)H MRS study.

Schizophr Res 2015 Feb;161(2-3):252-60. Epub 2014 des 24

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Mellesdal L, Gjestad R, Johnsen E, Jørgensen HA, Oedegaard KJ, Kroken RA, Mehlum L

Borderline Personality Disorder and Posttraumatic Stress Disorder at Psychiatric Discharge Predict General Hospital Admission for Self-Harm.

J Trauma Stress 2015 Dec;28(6):556-62. Epub 2015 nov 18

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Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH, , Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.

Am J Hum Genet 2015 Oct 1;97(4):576-92.

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Joa I, Gisselgård J, Brønnick K, McGlashan T, Johannessen JO

Primary prevention of psychosis through interventions in the symptomatic prodromal phase, a pragmatic Norwegian Ultra High Risk study.

BMC Psychiatry 2015;15():89. Epub 2015 apr 22

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Bulik-Sullivan BK, Loh PR, Finucane HK, Ripke S, Yang J, , Patterson N, Daly MJ, Price AL, Neale BM

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.

Nat Genet 2015 Mar;47(3):291-5. Epub 2015 feb 2

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Yeisen RA, Joa I, Johannessen JO, Opjordsmoen S

Use of medication algorithms in first episode psychosis: a naturalistic observational study.

Early Interv Psychiatry 2015 Jan 15. Epub 2015 jan 15

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Barder HE, Sundet K, Rund BR, Evensen J, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Melle I, Opjordsmoen S, Røssberg JI, Simonsen E, Vaglum P, McGlashan T, Friis SP

10 year course of IQ in first-episode psychosis: relationship between duration of psychosis and long-term intellectual trajectories.

Psychiatry Res 2015 Feb 28;225(3):515-21. Epub 2014 des 8

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Kallestad H, Jacobsen HB, Landrø NI, Borchgrevink Pc, Stiles TC

The role of insomnia in the treatment of chronic fatigue.

J Psychosom Res 2015 May;78(5):427-32. Epub 2014 des 5

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Kessler Ute, Schoeyen Helle K, Andreassen Ole A, Eide Geir E, Malt Ulrik F, Oedegaard Ketil J, Morken Gunnar, Sundet Kjetil, Vaaler Arne E

The effect of electroconvulsive therapy on neurocognitive function in treatment-resistant bipolar disorder depression.

J Clin Psychiatry 2014 Nov;75(11):e1306-13.

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Aas Monica, Pedersen Geir, Henry Chantal, Bjella Thomas, Bellivier Frank, Leboyer Marion, Kahn Jean-Pierre, Cohen Renaud F, Gard Sebastien, Aminoff Sofie R, Lagerberg Trine V, Andreassen Ole A, Melle Ingrid, Etain Bruno

Psychometric properties of the Affective Lability Scale (54 and 18-item version) in patients with bipolar disorder, first-degree relatives, and healthy controls.

J Affect Disord 2014 Oct 23;172C():375-380. Epub 2014 okt 23

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Aas Monica, Haukvik Unn K, Djurovic Srdjan, Tesli Martin, Athanasiu Lavinia, Bjella Thomas, Hansson Lars, Cattaneo Annamaria, Agartz Ingrid, Andreassen Ole A, Melle Ingrid

Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders.

J Psychiatr Res 2014 Dec;59():14-21. Epub 2014 aug 30

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Finseth P I, Morken G, Malt U F, Andreassen O A, Vaaler A E

Risk factors of cycle acceleration in acutely admitted patients with bipolar disorder.

Acta Psychiatr Scand 2014 Nov;130(5):388-96. Epub 2014 jun 24

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Tesli M, Espeseth T, Bettella F, Mattingsdal M, Aas M, Melle I, Djurovic S, Andreassen O A

Polygenic risk score and the psychosis continuum model.

Acta Psychiatr Scand 2014 Oct;130(4):311-7. Epub 2014 jun 25

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Bauer Michael, Glenn Tasha, Alda Martin, Andreassen Ole A, Angelopoulos Elias, Ardau Raffaella, Baethge Christopher, Bauer Rita, Bellivier Frank, Belmaker Robert H, Berk Michael, Bjella Thomas D, Bossini Letizia, Bersudsky Yuly, Cheung Eric Yat Wo, Conell Jörn, Del Zompo Maria, Dodd Seetal, Etain Bruno, Fagiolini Andrea, Frye Mark A, Fountoulakis Kostas N, Garneau-Fournier Jade, González-Pinto Ana, Harima Hirohiko, Hassel Stefanie, Henry Chantal, Iacovides Apostolos, Isometsä Erkki T, Kapczinski Flávio, Kliwicki Sebastian, König Barbara, Krogh Rikke, Kunz Mauricio, Lafer Beny, Larsen Erik R, Lewitzka Ute, Lopez-Jaramillo Carlos, MacQueen Glenda, Manchia Mirko, Marsh Wendy, Martinez-Cengotitabengoa Mónica, Melle Ingrid, Monteith Scott, Morken Gunnar, Munoz Rodrigo, Nery Fabiano G, O'Donovan Claire, Osher Yamima, Pfennig Andrea, Quiroz Danilo, Ramesar Raj, Rasgon Natalie, Reif Andreas, Ritter Philipp, Rybakowski Janusz K, Sagduyu Kemal, Scippa Ângela M, Severus Emanuel, Simhandl Christian, Stein Dan J, Strejilevich Sergio, Sulaiman Ahmad Hatim, Suominen Kirsi, Tagata Hiromi, Tatebayashi Yoshitaka, Torrent Carla, Vieta Eduard, Viswanath Biju, Wanchoo Mihir J, Zetin Mark, Whybrow Peter C

Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study.

J Affect Disord 2014 Oct;167():104-11. Epub 2014 mai 29

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Berg Akiah Ottesen, Andreassen Ole A, Aminoff Sofie Ragnhild, Romm Kristin Lie, Hauff Edvard, Melle Ingrid

The impact of immigration and visible minority status on psychosis symptom profile.

Soc Psychiatry Psychiatr Epidemiol 2014 Nov;49(11):1747-57. Epub 2014 jun 14

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Vaskinn Anja, Ueland Torill, Melle Ingrid, Agartz Ingrid, Andreassen Ole A, Sundet Kjetil

Neurocognitive Decrements are Present in Intellectually Superior Schizophrenia.

Front Psychiatry 2014;5():45. Epub 2014 mai 7

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Wirgenes Katrine Verena, Tesli Martin, Inderhaug Elin, Athanasiu Lavinia, Agartz Ingrid, Melle Ingrid, Hughes Timothy, Andreassen Ole Andreas, Djurovic Srdjan

ANK3 gene expression in bipolar disorder and schizophrenia.

Br J Psychiatry 2014 Sep;205(3):244-5. Epub 2014 mai 8

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Aas Monica, Aminoff Sofie R, Vik Lagerberg Trine, Etain Bruno, Agartz Ingrid, Andreassen Ole A, Melle Ingrid

Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma.

Psychiatry Res 2014 Aug 15;218(1-2):252-5. Epub 2014 apr 12

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Kvitland LR, Melle I, Aminoff SR, Lagerberg TV, Andreassen OA, Ringen PA

Cannabis use in first-treatment bipolar I disorder: relations to clinical characteristics.

Early Interv Psychiatry 2016 Feb;10(1):36-44. Epub 2014 apr 17

PMID: 24739233

Steen Nils Eiel, Methlie Paal, Lorentzen Steinar, Dieset Ingrid, Aas Monica, Nerhus Mari, Haram Marit, Agartz Ingrid, Melle Ingrid, Berg Jens P, Andreassen Ole A

Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders.

J Psychiatr Res 2014 May;52():57-62. Epub 2014 feb 4

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Bratlien Unni, Øie Merete, Haug Elisabeth, Møller Paul, Andreassen Ole A, Lien Lars, Melle Ingrid

Environmental factors during adolescence associated with later development of psychotic disorders - a nested case-control study.

Psychiatry Res 2014 Mar 30;215(3):579-85. Epub 2014 jan 9

PMID: 24495574

Finseth Per Ivar, Sønderby Ida Elken, Djurovic Srdjan, Agartz Ingrid, Malt Ulrik Fredrik, Melle Ingrid, Morken Gunnar, Andreassen Ole Andreas, Vaaler Arne Einar, Tesli Martin

Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia.

J Affect Disord 2014 Jul;163():110-4. Epub 2013 des 27

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Brandt Christine Lycke, Eichele Tom, Melle Ingrid, Sundet Kjetil, Server Andrés, Agartz Ingrid, Hugdahl Kenneth, Jensen Jimmy, Andreassen Ole A

Working memory networks and activation patterns in schizophrenia and bipolar disorder: comparison with healthy controls.

Br J Psychiatry 2014;204():290-8. Epub 2014 jan 16

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Thompson Paul M, Stein Jason L, Medland Sarah E, Hibar Derrek P, Vasquez Alejandro Arias, Renteria Miguel E, Toro Roberto, Jahanshad Neda, Schumann Gunter, Franke Barbara, Wright Margaret J, Martin Nicholas G, Agartz Ingrid, Alda Martin, Alhusaini Saud, Almasy Laura, Almeida Jorge, Alpert Kathryn, Andreasen Nancy C, Andreassen Ole A, Apostolova Liana G, Appel Katja, Armstrong Nicola J, Aribisala Benjamin, Bastin Mark E, Bauer Michael, Bearden Carrie E, Bergmann Orjan, Binder Elisabeth B, Blangero John, Bockholt Henry J, Bøen Erlend, Bois Catherine, Boomsma Dorret I, Booth Tom, Bowman Ian J, Bralten Janita, Brouwer Rachel M, Brunner Han G, Brohawn David G, Buckner Randy L, Buitelaar Jan, Bulayeva Kazima, Bustillo Juan R, Calhoun Vince D, Cannon Dara M, Cantor Rita M, Carless Melanie A, Caseras Xavier, Cavalleri Gianpiero L, Chakravarty M Mallar, Chang Kiki D, Ching Christopher R K, Christoforou Andrea, Cichon Sven, Clark Vincent P, Conrod Patricia, Coppola Giovanni, Crespo-Facorro 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Montgomery Grant W, Morris Derek W, Moses Eric K, Mueller Bryon A, Muñoz Maniega Susana, Mühleisen Thomas W, Müller-Myhsok Bertram, Mwangi Benson, Nauck Matthias, Nho Kwangsik, Nichols Thomas E, Nilsson Lars-Göran, Nugent Allison C, Nyberg Lars, Olvera Rene L, Oosterlaan Jaap, Ophoff Roel A, Pandolfo Massimo, Papalampropoulou-Tsiridou Melina, Papmeyer Martina, Paus Tomas, Pausova Zdenka, Pearlson Godfrey D, Penninx Brenda W, Peterson Charles P, Pfennig Andrea, Phillips Mary, Pike G Bruce, Poline Jean-Baptiste, Potkin Steven G, Pütz Benno, Ramasamy Adaikalavan, Rasmussen Jerod, Rietschel Marcella, Rijpkema Mark, Risacher Shannon L, Roffman Joshua L, Roiz-Santiañez Roberto, Romanczuk-Seiferth Nina, Rose Emma J, Royle Natalie A, Rujescu Dan, Ryten Mina, Sachdev Perminder S, Salami Alireza, Satterthwaite Theodore D, Savitz Jonathan, Saykin Andrew J, Scanlon Cathy, Schmaal Lianne, Schnack Hugo G, Schork Andrew J, Schulz S Charles, Schür Remmelt, Seidman Larry, Shen Li, Shoemaker Jody M, 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The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.

Brain Imaging Behav 2014 Jun;8(2):153-82.

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Haug Elisabeth, Øie Merete, Andreassen Ole A, Bratlien Unni, Raballo Andrea, Nelson Barnaby, Møller Paul, Melle Ingrid

Anomalous self-experiences contribute independently to social dysfunction in the early phases of schizophrenia and psychotic bipolar disorder.

Compr Psychiatry 2014 Apr;55(3):475-82. Epub 2013 nov 28

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Ruderfer D M, Fanous A H, Ripke S, McQuillin A, Amdur R L, Schizophrenia Working Group of Psychiatric Genomics Consortium, Bipolar Disorder Working Group of Psychiatric Genomics Consortium, Cross-Disorder Working Group of Psychiatric Genomics Consortium, Gejman P V, O'Donovan M C, Andreassen O A, Djurovic S, Hultman C M, Kelsoe J R, Jamain S, Landén M, Leboyer M, Nimgaonkar V, Nurnberger J, Smoller J W, Craddock N, Corvin A, Sullivan P F, Holmans P, Sklar P, Kendler K S

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.

Mol Psychiatry 2014 Sep;19(9):1017-24. Epub 2013 nov 26

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Lagerberg Trine Vik, Kvitland Levi Røstad, Aminoff Sofie R, Aas Monica, Ringen Petter Andreas, Andreassen Ole Andreas, Melle Ingrid

Indications of a dose-response relationship between cannabis use and age at onset in bipolar disorder.

Psychiatry Res 2014 Jan 30;215(1):101-4. Epub 2013 okt 30

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Lange Elisabeth Heffermehl, Nesvåg Ragnar, Ringen Petter Andreas, Hartberg Cecilie Bhandari, Haukvik Unn Kristin, Andreassen Ole Andreas, Melle Ingrid, Agartz Ingrid

One year follow-up of alcohol and illicit substance use in first-episode psychosis: does gender matter?

Compr Psychiatry 2014 Feb;55(2):274-82. Epub 2013 okt 19

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Aas M, Etain B, Bellivier F, Henry C, Lagerberg T, Ringen A, Agartz I, Gard S, Kahn J-P, Leboyer M, Andreassen O A, Melle I

Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders.

Psychol Med 2014 Jun;44(8):1653-62. Epub 2013 sep 13

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Common variant at 16p11.2 conferring risk of psychosis.

Mol Psychiatry 2014 Jan;19(1):108-14. Epub 2012 nov 20

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Schizophrenia Working Group of the Psychiatric Genomics Consortium

Biological insights from 108 schizophrenia-associated genetic loci.

Nature 2014 Jul 24;511(7510):421-7. Epub 2014 jul 22

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Krane-Gartiser Karoline, Henriksen Tone Elise Gjotterud, Morken Gunnar, Vaaler Arne, Fasmer Ole Bernt

Actigraphic assessment of motor activity in acutely admitted inpatients with bipolar disorder.

PLoS One 2014;9(2):e89574. Epub 2014 feb 20

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Løberg Else-Marie, Helle Siri, Nygård Merethe, Berle Jan Øystein, Kroken Rune A, Johnsen Erik

The Cannabis Pathway to Non-Affective Psychosis may Reflect Less Neurobiological Vulnerability.

Front Psychiatry 2014;5():159. Epub 2014 nov 18

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Kroken Rune A, Kjelby Eirik, Wentzel-Larsen Tore, Mellesdal Liv S, Jørgensen Hugo A, Johnsen Erik

Time to discontinuation of antipsychotic drugs in a schizophrenia cohort: influence of current treatment strategies.

Ther Adv Psychopharmacol 2014 Dec;4(6):228-39.

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Helle Siri, Gjestad Rolf, Johnsen Erik, Kroken Rune Andreas, Jørgensen Hugo A, Løberg Else-Marie

Cognitive changes in patients with acute phase psychosis--effects of illicit drug use.

Psychiatry Res 2014 Dec 30;220(3):818-24. Epub 2014 sep 8

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Falkenberg Liv E, Westerhausen René, Craven Alexander R, Johnsen Erik, Kroken Rune A, L Berg Else-Marie, Specht Karsten, Hugdahl Kenneth

Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia.

Neuroimage Clin 2014;4():576-84. Epub 2014 apr 2

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Kroken Rune A, Løberg Else-Marie, Drønen Tore, Grüner Renate, Hugdahl Kenneth, Kompus Kristiina, Skrede Silje, Johnsen Erik

A critical review of pro-cognitive drug targets in psychosis: convergence on myelination and inflammation.

Front Psychiatry 2014;5():11. Epub 2014 feb 4

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Schumann Gunter, Binder Elisabeth B, Holte Arne, de Kloet E Ronald, Oedegaard Ketil J, Robbins Trevor W, Walker-Tilley Tom R, Bitter Istvan, Brown Verity J, Buitelaar Jan, Ciccocioppo Roberto, Cools Roshan, Escera Carles, Fleischhacker Wolfgang, Flor Herta, Frith Chris D, Heinz Andreas, Johnsen Erik, Kirschbaum Clemens, Klingberg Torkel, Lesch Klaus-Peter, Lewis Shon, Maier Wolfgang, Mann Karl, Martinot Jean-Luc, Meyer-Lindenberg Andreas, Müller Christian P, Müller Walter E, Nutt David J, Persico Antonio, Perugi Giulio, Pessiglione Mathias, Preuss Ulrich W, Roiser Jonathan P, Rossini Paolo M, Rybakowski Janusz K, Sandi Carmen, Stephan Klaas E, Undurraga Juan, Vieta Eduard, van der Wee Nic, Wykes Til, Haro Josep Maria, Wittchen Hans Ulrich

Stratified medicine for mental disorders.

Eur Neuropsychopharmacol 2014 Jan;24(1):5-50. Epub 2013 okt 4

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Juuhl-Langseth Monica, Holmén Aina, Thormodsen Rune, Oie Merete, Rund Bjørn Rishovd

Relative stability of neurocognitive deficits in early onset schizophrenia spectrum patients.

Schizophr Res 2014 Jul;156(2-3):241-7. Epub 2014 mai 5

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Jacobsen Kaya K, Nievergelt Caroline M, Zayats Tetyana, Greenwood Tiffany A, Anttila Verneri, Akiskal Hagop S, BiGS Consortium, IHG Consortium, BiGS Consortium Co-Authors include:, IHG Consortium Co-Authors include:, Haavik Jan, Bernt Fasmer Ole, Kelsoe John R, Johansson Stefan, Oedegaard Ketil J, BiGS Consortium Co-Authors include, IHG Consortium Co-Authors include

Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder.

J Affect Disord 2014 Oct 12;172C():453-461. Epub 2014 okt 12

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Lencz T, Knowles E, Davies G, Guha S, Liewald D C, Starr J M, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, Derosse Pamela, Lundervold A, Steen V M, John M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson J G, Giegling I, Konte B, Ikeda M, Roussos P, Giakoumaki S, Burdick K E, Payton A, Ollier W, Horan M, Donohoe G, Morris D, Corvin A, Gill M, Pendleton N, Iwata N, Darvasi A, Bitsios P, Rujescu D, Lahti J, Hellard S L, Keller M C, Andreassen O A, Deary I J, Glahn D C, Malhotra A K

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).

Mol Psychiatry 2014 Feb;19(2):168-74. Epub 2013 des 17

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Haukvik UK, Westlye LT, Mørch-Johnsen L, Jørgensen KN, Lange EH, Dale AM, Melle I, Andreassen OA, Agartz I

In vivo hippocampal subfield volumes in schizophrenia and bipolar disorder.

Biol Psychiatry 2015 Mar 15;77(6):581-8. Epub 2014 jul 3

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Cohen Alex S, Mitchell Kyle R, Elvevåg Brita

What do we really know about blunted vocal affect and alogia? A meta-analysis of objective assessments.

Schizophr Res 2014 Nov;159(2-3):533-8. Epub 2014 sep 26

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Rosenstein Mark, Diaz-Asper Catherine, Foltz Peter W, Elvevåg Brita

A computational language approach to modeling prose recall in schizophrenia.

Cortex 2014 Jun;55():148-66. Epub 2014 feb 8

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Nicodemus Kristin K, Elvevåg Brita, Foltz Peter W, Rosenstein Mark, Diaz-Asper Catherine, Weinberger Daniel R

Category fluency, latent semantic analysis and schizophrenia: a candidate gene approach.

Cortex 2014 Jun;55():182-91. Epub 2013 des 20

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Voorspoels Wouter, Storms Gert, Longenecker Julia, Verheyen Steven, Weinberger Daniel R, Elvevåg Brita

Deriving semantic structure from category fluency: clustering techniques and their pitfalls.

Cortex 2014 Jun;55():130-47. Epub 2013 okt 10

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Holshausen Katherine, Harvey Philip D, Elvevåg Brita, Foltz Peter W, Bowie Christopher R

Latent semantic variables are associated with formal thought disorder and adaptive behavior in older inpatients with schizophrenia.

Cortex 2014 Jun;55():88-96. Epub 2013 feb 19

PMID: 23510635

Tagamets Malle A, Cortes Carlos R, Griego Jacqueline A, Elvevåg Brita

Neural correlates of the relationship between discourse coherence and sensory monitoring in schizophrenia.

Cortex 2014 Jun;55():77-87. Epub 2013 jul 22

PMID: 23969195

Ringen Petter Andreas, Engh John A, Birkenaes Astrid B, Dieset Ingrid, Andreassen Ole A

Increased mortality in schizophrenia due to cardiovascular disease - a non-systematic review of epidemiology, possible causes, and interventions.

Front Psychiatry 2014;5():137. Epub 2014 sep 26

PMID: 25309466

Sviland,Åse. Johannessen, Jan Olav. Joa, Inge

Hvordan ungdom og unge voksne som står i fare for å utvikle psykose, opplever egen skole og sosial fungering, etter å ha deltatt i psykoedukativ familiebehandling. En kvalitativ studie

Nordisk Sygeplejeforskning, ÅRGANG 7, NR. 1-2017, S. 35–47 DOI: 10.18261/ISSN.1892-2686-2017-01-04

Doktorgrader
Ute Kessler

Electroconvulsive therapy for bipolar disorder depression: Effects on depressive symptoms and cognitive

Disputert:
november 2014
Hovedveileder:
Arne Vaaler
Morten Mattingsdal

Functional Profiling of Single-Nucleotide Polymorphisms Associated with Bipolar Disorder

Disputert:
januar 2014
Hovedveileder:
Ole Andreas Andreassen
Deltagere
  • Merete Glenne Øie Forskningsgruppeleder
  • Erik Johnsen Forskningsgruppeleder
  • Anne Høye Forskningsgruppeleder
  • Nils Eiel Steen Hovedveileder
  • Jan Olav Johannessen Forskningsgruppeleder
  • Ketil Joachim Ødegaard Forskningsgruppeleder
  • Gunnar Morken Forskningsgruppeleder
  • Ole Andreas Andreassen Prosjektleder
  • Ted Reichborn-Kjennerud Forskningsgruppeleder
  • Arne Einar Vaaler Forskningsgruppeleder
  • Brita Elvevåg Forskningsgruppeleder
  • John Engh Forsker (annen finansiering)
  • Petter Andreas Ringen Forskningsgruppeleder
  • Inge Joa Forskningsgruppeleder
  • Ingrid Melle Forsker (annen finansiering)
  • Tor Ketil Larsen Forsker (annen finansiering)

eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT

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