Dissecting the role of long non-coding RNAs and miRNAs in breast cancer development, progression and response to therapy
Subtype-specific micro-RNA expression signatures in breast cancer progression.
Int J Cancer 2016 Sep 01;139(5):1117-28. Epub 2016 mai 9
Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
Nature 2016 06 02;534(7605):47-54.
Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes.
Cancer Metab 2016;4():12. Epub 2016 jun 27
Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer.
Cell Rep 2016 Jul 26;16(4):1166-79. Epub 2016 jul 7
LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.
EMBO Mol Med 2016 Sep 01;8(9):1052-64. Epub 2016 sep 1
DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival.
Oncotarget 2017 Jan 03;8(1):1074-1082.
MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase.
Mol Oncol 2015 Jun;9(6):1056-70. Epub 2015 jan 27
Targeted exploration and analysis of large cross-platform human transcriptomic compendia.
Nat Methods 2015 Mar;12(3):211-4, 3 p following 214. Epub 2015 jan 12
Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer.
Genome Med 2015;7(1):21. Epub 2015 feb 2
Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo.
Br J Cancer 2014 Nov 25;111(11):2142-51. Epub 2014 sep 30
Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c.
Br J Cancer 2014 Apr 15;110(8):2072-80. Epub 2014 feb 27
Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.
Cancer Cell 2014 Dec 8;26(6):863-79.
Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
Accepted for publication in Breast Cancer Research
The lncRNA LIMT/LINC01089 is an EGF-downregulated metastasis inhibitor weakly expressed in aggressive subtypes of breast cancer
(Re)submitted to Cancer Discovery, 2015
MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers.
Submitted to PLOS ONE, 2015
Subtype-specific micro-RNA expression signatures in breast cancer progression
Submitted to Int J Cancer, 2015
Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes
Submitted to BMC Cancer
Molecular features of subtype-specific progression from ductal carcinoma in situ to invasive breast cancer
Submitted to Cell Reports, 2015
A compendium of 560 breast cancers
Submitted to Nature, 2015
• Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer
Accepted for publication in Genome Medicine
• MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase
Accepted for publication in Molecular Oncology
• Global lncRNA profiling identifies LOC338799 as an EGF-regulated long non-coding RNA depleted in aggressive breast tumors(...)
Submitted to EMBO MOL MEDICINE
• The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells(...)
Genomics data, Volume 2, December 2014, Pages 249–253