Healthy Brain Ageing Centre (HBAC)
- Prosjektnummer
- 2014050
- Ansvarlig person
- Tone Tønjum
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Regionalt forskningsnettverk
- Helsekategori
- Forskningsaktivitet
Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation.
Mol Cell Neurosci 2016 Dec;77():47-52. Epub 2016 okt 14
PMID: 27751903
Cortical astrogliosis and increased perivascular aquaporin-4 in idiopathic intracranial hypertension.
Brain Res 2016 Aug 01;1644():161-75. Epub 2016 mai 14
PMID: 27188961
Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease.
Mol Brain 2016 May 28;9(1):61. Epub 2016 mai 28
PMID: 27234294
Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7.
BMC Evol Biol 2016 Jun 30;16(1):146. Epub 2016 jun 30
PMID: 27363525
Throat culture positivity rate and antibiotic susceptibility pattern of beta-hemolytic streptococci in children on secondary prophylaxis for rheumatic heart disease.
BMC Infect Dis 2016 Sep 23;16(1):510. Epub 2016 sep 23
PMID: 27663649
Characterization of the Neisseria meningitidis Helicase RecG.
PLoS One 2016;11(10):e0164588. Epub 2016 okt 13
PMID: 27736945
The Mycobacterium tuberculosis transcriptional landscape under genotoxic stress.
BMC Genomics 2016 Oct 10;17(1):791. Epub 2016 okt 10
PMID: 27724857
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain.
Neurobiol Aging 2016 Dec;48():34-47. Epub 2016 aug 18
PMID: 27639119
Erratum to: Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease.
Neurochem Res 2016 Jun;41(6):1237.
PMID: 27113043
Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease.
Neurochem Res 2016 Jun;41(6):1229-36. Epub 2015 des 16
PMID: 26677077
Observations on hippocampal mossy cells in mink (Neovison vison) with special reference to dendrites ascending to the granular and molecular layers.
Hippocampus 2016 Feb;26(2):229-45. Epub 2015 sep 12
PMID: 26286893
3D Reconstructed Cyto-, Muscarinic M2 Receptor, and Fiber Architecture of the Rat Brain Registered to the Waxholm Space Atlas.
Front Neuroanat 2016;10():51. Epub 2016 mai 3
PMID: 27199682
Brain-Wide Mapping of Axonal Connections: Workflow for Automated Detection and Spatial Analysis of Labeling in Microscopic Sections.
Front Neuroinform 2016;10():11. Epub 2016 apr 19
PMID: 27148038
E-learning resources in Myanmar.
Lancet 2016 12 17;388(10063):2990-2991.
PMID: 27998528
Factors determining the density of AQP4 water channel molecules at the brain-blood interface.
Brain Struct Funct 2016 Sep 15. Epub 2016 sep 15
PMID: 27629271
Osmotherapy With Hypertonic Saline Attenuates Global Cerebral Edema Following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4.
Crit Care Med 2016 Aug;44(8):e702-10.
PMID: 27035238
Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.
PLoS One 2016;11(3):e0152833. Epub 2016 mar 31
PMID: 27031698
Conivaptan, a Selective Arginine Vasopressin V1a and V2 Receptor Antagonist Attenuates Global Cerebral Edema Following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4.
Neurocrit Care 2016 Apr;24(2):273-82.
PMID: 26732270
Amyloid Dysmetabolism Relates to Reduced Glucose Uptake in White Matter Hyperintensities.
Front Neurol 2016;7():209. Epub 2016 nov 21
PMID: 27917152
Cerebrospinal Fluid Alzheimer's Disease Biomarkers Across the Spectrum of Lewy Body Diseases: Results from a Large Multicenter Cohort.
J Alzheimers Dis 2016 Aug 18;54(1):287-95.
PMID: 27567832
Overview of the membrane-associated RING-CH (MARCH) E3 ligase family.
N Biotechnol 2016 Dec 14. Epub 2016 des 14
PMID: 27988304
Malonate in the nucleotide-binding site traps human AKAP18?/d in a novel conformational state.
Acta Crystallogr F Struct Biol Commun 2016 Aug;72(Pt 8):591-7. Epub 2016 jul 13
PMID: 27487922
Secretion of the Intimin Passenger Domain Is Driven by Protein Folding.
J Biol Chem 2016 Sep 16;291(38):20096-112. Epub 2016 jul 27
PMID: 27466361
Crystal Structure of a Two-domain Fragment of Hepatocyte Growth Factor Activator Inhibitor-1: FUNCTIONAL INTERACTIONS BETWEEN THE KUNITZ-TYPE INHIBITOR DOMAIN-1 AND THE NEIGHBORING POLYCYSTIC KIDNEY DISEASE-LIKE DOMAIN.
J Biol Chem 2016 Jul 01;291(27):14340-55. Epub 2016 mai 6
PMID: 27189939
Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2.
Biochem Biophys Res Commun 2016 Jul 22;476(2):102-7. Epub 2016 mai 11
PMID: 27178209
The magnesium transporter A is activated by cardiolipin and is highly sensitive to free magnesium in vitro.
Elife 2016 Jan 18;5(). Epub 2016 jan 18
PMID: 26780187
White matter integrity as a marker for cognitive plasticity in aging.
Neurobiol Aging 2016 Nov;47():74-82. Epub 2016 jul 15
PMID: 27565301
Neurodevelopmental origins of lifespan changes in brain and cognition.
Proc Natl Acad Sci U S A 2016 Aug 16;113(33):9357-62. Epub 2016 jul 18
PMID: 27432992
Longitudinal Changes in White Matter Tract Integrity across the Adult Lifespan and Its Relation to Cortical Thinning.
PLoS One 2016;11(6):e0156770. Epub 2016 jun 2
PMID: 27253393
Waxholm Space atlas of the rat brain hippocampal region: three-dimensional delineations based on magnetic resonance and diffusion tensor imaging.
Neuroimage 2015 Mar;108():441-9. Epub 2015 jan 10
PMID: 25585022
Postnatal development of the molecular complex underlying astrocyte polarization.
Brain Struct Funct 2015 Jul;220(4):2087-101. Epub 2014 apr 29
PMID: 24777283
Enzymatic detection and quantification assay of isatin, a putative stress biomarker in blood.
ACS Chem Neurosci 2015 Aug 19;6(8):1353-60. Epub 2015 mai 5
PMID: 25891478
Coating-dependent induction of cytotoxicity and genotoxicity of iron oxide nanoparticles.
Nanotoxicology 2015 May;9 Suppl 1():44-56. Epub 2013 nov 14
PMID: 24228750
Staphylococcal a-hemolysin is neurotoxic and causes lysis of brain cells in vivo and in vitro.
Neurotoxicology 2015 May;48():61-7. Epub 2015 mar 7
PMID: 25757835
A three-plane architectonic atlas of the rat hippocampal region.
Hippocampus 2015 Jul;25(7):838-57. Epub 2015 jan 20
PMID: 25533645
The Inner Membrane Protein PilG Interacts with DNA and the Secretin PilQ in Transformation.
PLoS One 2015;10(8):e0134954. Epub 2015 aug 6
PMID: 26248334
Anatomical landmarks for registration of experimental image data to volumetric rodent brain atlasing templates.
J Neurosci Methods 2015 Jan 30;240():161-9. Epub 2014 nov 18
PMID: 25445058
Addendum to “Waxholm Space atlas of the Sprague Dawley rat brain” [NeuroImage 97 (2014) 374-386].
Neuroimage 2015 Jan 15;105():561-2.
PMID: 25635280
Three-Dimensional Histology Volume Reconstruction of Axonal Tract Tracing Data: Exploring Topographical Organization in Subcortical Projections from Rat Barrel Cortex.
PLoS One 2015;10(9):e0137571. Epub 2015 sep 23
PMID: 26398192
Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex.
Brain Struct Funct 2015 Apr 14. Epub 2015 apr 14
PMID: 25869275
Feeding the human brain model.
Curr Opin Neurobiol 2015 Jun;32():107-14. Epub 2015 feb 26
PMID: 25725212
Development and aging of cortical thickness correspond to genetic organization patterns.
Proc Natl Acad Sci U S A 2015 Dec 15;112(50):15462-7. Epub 2015 nov 2
PMID: 26575625
Premises of plasticity - And the loneliness of the medial temporal lobe.
Neuroimage 2015 Oct 24. Epub 2015 okt 24
PMID: 26505299
Cognitive function of youths born to mothers with opioid and poly-substance abuse problems during pregnancy.
Child Neuropsychol 2015 Oct 16. Epub 2015 okt 16
PMID: 26471942
Functional connectivity change across multiple cortical networks relates to episodic memory changes in aging.
Neurobiol Aging 2015 Dec;36(12):3255-68. Epub 2015 aug 24
PMID: 26363813
Longitudinal cognitive development of children born to mothers with opioid and polysubstance use.
Pediatr Res 2015 Sep;78(3):330-5. Epub 2015 mai 15
PMID: 25978800
Intracortical Posterior Cingulate Myelin Content Relates to Error Processing: Results from T1- and T2-Weighted MRI Myelin Mapping and Electrophysiology in Healthy Adults.
Cereb Cortex 2016 Jun;26(6):2402-10. Epub 2015 apr 2
PMID: 25840423
Mechanisms underlying encoding of short-lived versus durable episodic memories.
J Neurosci 2015 Apr 1;35(13):5202-12.
PMID: 25834046
Immunogold characteristics of VGLUT3-positive GABAergic nerve terminals suggest corelease of glutamate.
J Comp Neurol 2015 Dec 15;523(18):2698-713. Epub 2015 jul 1
PMID: 26010578
Neuroglial Transmission.
Physiol Rev 2015 Jul;95(3):695-726.
PMID: 26084688
Localisation of N-acetylaspartate in oligodendrocytes/myelin.
Brain Struct Funct 2015 Mar;220(2):899-917. Epub 2013 des 31
PMID: 24379086
Dynamics of Ionic Shifts in Cortical Spreading Depression.
Cereb Cortex 2015 Nov;25(11):4469-76. Epub 2015 apr 2
PMID: 25840424
Augmentation of Ca(2+) signaling in astrocytic endfeet in the latent phase of temporal lobe epilepsy.
Front Cell Neurosci 2015;9():49. Epub 2015 feb 25
PMID: 25762896
Stimulation-evoked Ca2+ signals in astrocytic processes at hippocampal CA3-CA1 synapses of adult mice are modulated by glutamate and ATP.
J Neurosci 2015 Feb 18;35(7):3016-21.
PMID: 25698739
Mechanisms underlying AQP4 accumulation in astrocyte endfeet.
Glia 2015 Jun 29. Epub 2015 jun 29
PMID: 26119521
Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease.
Clin Exp Gastroenterol 2015;8():49-67. Epub 2015 jan 9
PMID: 25624769
Bridging the gap between clinical neuroscience and cognitive rehabilitation: the role of cognitive training, models of neuroplasticity and advanced neuroimaging in future brain injury rehabilitation.
NeuroRehabilitation 2014;34(1):81-5.
PMID: 24284460
Blood markers of fatty acids and vitamin D, cardiovascular measures, body mass index, and physical activity relate to longitudinal cortical thinning in normal aging.
Neurobiol Aging 2014 May;35(5):1055-64. Epub 2013 nov 21
PMID: 24332985
Maturation of Cortico-Subcortical Structural Networks--Segregation and Overlap of Medial Temporal and Fronto-Striatal Systems in Development.
Cereb Cortex 2014 Jan 15. Epub 2014 jan 15
PMID: 24436319
What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus.
Prog Neurobiol 2014 Jun;117():20-40. Epub 2014 feb 16
PMID: 24548606
The CNS white matter.
Neuroscience 2014 Sep 12;276():1. Epub 2014 mar 17
PMID: 24650921
The Roots of Alzheimer's Disease: Are High-Expanding Cortical Areas Preferentially Targeted?
Cereb Cortex 2014 Mar 21. Epub 2014 mar 21
PMID: 24658616
Effects of cognitive training on gray matter volumes in memory clinic patients with subjective memory impairment.
J Alzheimers Dis 2014;41(3):779-91.
PMID: 24685630
The perinatal outcome of children born to women with substance dependence detoxified in residential treatment during pregnancy.
J Addict Dis 2014;33(2):114-23.
PMID: 24717065
Regional hippocampal volumes and development predict learning and memory.
Dev Neurosci 2014;36(3-4):161-74. Epub 2014 mai 27
PMID: 24902771
Differential longitudinal changes in cortical thickness, surface area and volume across the adult life span: regions of accelerating and decelerating change.
J Neurosci 2014 Jun 18;34(25):8488-98.
PMID: 24948804
Development of hippocampal subfield volumes from 4 to 22 years.
Hum Brain Mapp 2014 Nov;35(11):5646-57. Epub 2014 jun 30
PMID: 24976170
Unraveling the secrets of white matter--bridging the gap between cellular, animal and human imaging studies.
Neuroscience 2014 Sep 12;276():2-13. Epub 2014 jul 6
PMID: 25003711
Poor sleep quality is associated with increased cortical atrophy in community-dwelling adults.
Neurology 2014 Sep 9;83(11):967-73. Epub 2014 sep 3
PMID: 25186857
Organizing Principles of Human Cortical Development-Thickness and Area from 4 to 30 Years: Insights from Comparative Primate Neuroanatomy.
Cereb Cortex 2014 Sep 21. Epub 2014 sep 21
PMID: 25246511
Mother-Child Interaction and Early Language Skills in Children Born to Mothers with Substance Abuse and Psychiatric Problems.
Child Psychiatry Hum Dev 2014 Oct 10. Epub 2014 okt 10
PMID: 25300194
Accelerated changes in white matter microstructure during aging: a longitudinal diffusion tensor imaging study.
J Neurosci 2014 Nov 12;34(46):15425-36.
PMID: 25392509
A common brain network links development, aging, and vulnerability to disease.
Proc Natl Acad Sci U S A 2014 Dec 9;111(49):17648-53. Epub 2014 nov 24
PMID: 25422429
Reorganization of supramammillary-hippocampal pathways in the rat pilocarpine model of temporal lobe epilepsy: evidence for axon terminal sprouting.
Brain Struct Funct 2014 Jun 3. Epub 2014 jun 3
PMID: 24889162
Research into glia and epilepsy.
Tidsskr Nor Laegeforen 2014 Jan 14;134(1):6.
PMID: 24429739
Deletion of aquaporin-4 increases extracellular K(+) concentration during synaptic stimulation in mouse hippocampus.
Brain Struct Funct 2014 Apr 18. Epub 2014 apr 18
PMID: 24744149
A proton wire and water channel revealed in the crystal structure of isatin hydrolase.
J Biol Chem 2014 Aug 1;289(31):21351-9. Epub 2014 jun 10
PMID: 24917679
Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties.
Cancer Res 2014 Oct 15;74(20):5758-71. Epub 2014 sep 26
PMID: 25261234
GABA is localized in dopaminergic synaptic vesicles in the rodent striatum.
Brain Struct Funct 2014 Nov;219(6):1901-12. Epub 2013 jul 14
PMID: 23851655
White matter integrity and cognition in Parkinson's disease: a cross-sectional study.
BMJ Open 2014;4(1):e003976. Epub 2014 jan 21
PMID: 24448846
The Combination of Dysexecutive and Amnestic Deficits Strongly Predicts Conversion to Dementia in Young Mild Cognitive Impairment Patients: A Report from the Gothenburg-Oslo MCI Study.
Dement Geriatr Cogn Dis Extra 2014 Jan;4(1):76-85. Epub 2014 apr 9
PMID: 24847346
Identification of peptide products from enzymatic degradation of amyloid beta.
Biochimie 2014 Oct;105():216-20. Epub 2014 jul 7
PMID: 25010651
Brain-wide map of efferent projections from rat barrel cortex.
Front Neuroinform 2014;8():5. Epub 2014 feb 5
PMID: 24550819
Waxholm Space atlas of the Sprague Dawley rat brain.
Neuroimage 2014 Aug 15;97():374-86. Epub 2014 apr 12
PMID: 24726336
Interoperable atlases of the human brain.
Neuroimage 2014 Oct 1;99():525-32. Epub 2014 jun 15
PMID: 24936682
Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism.
Cereb Cortex 2014 Oct;24(10):2784-95. Epub 2013 mai 21
PMID: 23696276
White matter lactate--does it matter?
Neuroscience 2014 Sep 12;276():109-16. Epub 2013 okt 12
PMID: 24125892
Lactate transport and receptor actions in cerebral malaria.
Front Neurosci 2014;8():125. Epub 2014 mai 19
PMID: 24904266
Monocarboxylate transport matters.
N Engl J Med 2014 Nov 13;371(20):1931-2.
PMID: 25390745
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.
Cell Metab 2014 Nov 4;20(5):840-55. Epub 2014 nov 4
PMID: 25440059
Mathematical and live meningococcal models for simple sequence repeat dynamics - coherent predictions and observations.
PLoS One 2014;9(7):e101637. Epub 2014 jul 7
PMID: 24999629
Brain infection with Staphylococcus aureus leads to high extracellular levels of glutamate, aspartate, ?-aminobutyric acid, and zinc.
J Neurosci Res 2014 Dec;92(12):1792-800. Epub 2014 jul 4
PMID: 25043715
A non-canonical mismatch repair pathway in prokaryotes.
Nature Communications 8:14246, 2017
The role of mitochondrial oxidative phosphorylation in Alzheimer's disease.
Curr Med Chem Volume 24, 2017
CSF neurofilament light levels predict hippocampal atrophy in cognitively healthy older adults.
Neurobiol Aging. 2017 Jan;49:138-144.
Relationship between structural and functional connectivity change across the adult lifespan: A longitudinal investigation.
Hum Brain Mapp. 2017 Jan;38(1):561-573.
Regulation and dysregulation of AQP4 expression in astrocytes
- Disputert:
- oktober 2015
- Hovedveileder:
- Mahmood Reza Amiri Moghadam
Water transporting membrane domains: development and pathophysiological significance
- Disputert:
- september 2015
- Hovedveileder:
- Mahmood Reza Amiri Moghadam
Excitatory and Inhibitory Synaptic Alterations in the Hippocampus of Transgenic DNA Glycosylase Mouse Models
- Disputert:
- oktober 2014
- Hovedveileder:
- Linda Hildegard Bergersen
- Tormod Fladby Prosjektdeltaker
- Kristine Beate Walhovd Prosjektdeltaker
- Jens Preben Morth Prosjektdeltaker
- Mahmood Reza Amiri Moghadam Prosjektdeltaker
- Jan Gunnar Bjålie Prosjektdeltaker
- Vidar Gundersen Prosjektdeltaker
- Erlend Arnulf Nagelhus Prosjektdeltaker
- Tone Tønjum Prosjektleder
- Mahmood Amiry-Moghaddam Prosjektdeltaker
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