Epigenomic signatures of treatment response in rheumatoid arthritis patients
- Prosjektnummer
- 2014116
- Ansvarlig person
- Benedicte Alexandra Lie
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Inflammatory and Immune System, Musculoskeletal
- Forskningsaktivitet
- 2. Aetiology, 6. Treatment Evaluation
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Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset.
Ann Rheum Dis 2022 Aug;81(8):1085. Epub 2022 apr 25
PMID: 35470158
Methotrexate Treatment of Newly Diagnosed RA Patients Is Associated With DNA Methylation Differences at Genes Relevant for Disease Pathogenesis and Pharmacological Action.
Front Immunol 2021;12():713611. Epub 2021 nov 18
PMID: 34867944 - Inngår i doktorgradsavhandlingen
Polymorphisms in the TP53-MDM2-MDM4-axis in patients with rheumatoid arthritis.
Gene 2021 Aug 15;793():145747. Epub 2021 mai 30
PMID: 34077778
Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4
Front Immunol 2020;11():194. Epub 2020 feb 14
PMID: 32117312 - Inngår i doktorgradsavhandlingen
Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells.
BMC Genomics 2020 May 11;21(1):350. Epub 2020 mai 11
PMID: 32393182
Genome-wide meta-analysis reveals shared new
Ann Rheum Dis 2019 03;78(3):311-319. Epub 2018 des 20
PMID: 30573655
Lack of Association among Peptidyl Arginine Deiminase Type 4 Autoantibodies,
J Rheumatol 2018 Aug;45(9):1211-1219. Epub 2018 jun 1
PMID: 29858238
- Benedicte Alexandra Lie Hovedveileder
- Bettina Kulle Andreassen Medveileder
- Marthe Thoresen Mæhlen Medveileder
- Siri Tennebø Flåm Prosjektdeltaker
- Fatima Heinicke Prosjektdeltaker
- Kari Guderud Doktorgradsstipendiat (annen finansiering)
- Line Hagen Sunde Doktorgradsstipendiat (finansiert av denne bevilgning)
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport