Regulation of bile duct inflammation
- Prosjektnummer
- 2015015
- Ansvarlig person
- Espen Melum
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Karrierestipend
- Helsekategori
- Inflammatory and Immune System, Oral and Gastrointestinal
- Forskningsaktivitet
- 1. Underpinning
NO
no
NEI
NEI
Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis.
Hepatol Commun 2022 Sep;6(9):2538. Epub 2022 jun 20
PMID: 35726350
Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells.
Clin Exp Immunol 2021 02;203(2):304-314. Epub 2020 nov 16
PMID: 33089489
Mucosal-associated invariant T-cell tumor infiltration predicts long-term survival in cholangiocarcinoma.
Hepatology 2021 Oct 30. Epub 2021 okt 30
PMID: 34719787
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis.
Sci Transl Med 2021 02 24;13(582).
PMID: 33627483
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver.
Science 2021 02 19;371(6531):839-846.
PMID: 33602855
Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Nat Immunol 2019 12;20(12):1644-1655. Epub 2019 okt 21
PMID: 31636468
Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree.
Am J Physiol Gastrointest Liver Physiol 2018 Mar 01;314(3):G349-G359. Epub 2017 des 6
PMID: 29212771
Natural killer T cells mediate inflammation in the bile ducts.
Mucosal Immunol 2018 11;11(6):1582-1590. Epub 2018 aug 16
PMID: 30115993
Intact CD100-CD72 Interaction Necessary for TCR-Induced T Cell Proliferation.
Front Immunol 2017;8():765. Epub 2017 jun 30
PMID: 28713384
The biliary epithelium presents antigens to and activates natural killer T cells.
Hepatology 2015 Oct;62(4):1249-59. Epub 2015 mai 20
PMID: 25855031
The role of natural killer T cells in biliary immunology and disease
- Disputert:
- juni 2021
- Hovedveileder:
- Espen Melum
The role of natural killer T cells in biliary immunology and disease
- Disputert:
- november 2020
- Hovedveileder:
- Espen Melum
- Natalie Lie Berntsen Doktorgradsstipendiat (annen finansiering)
- Bjarte Fosby Prosjektdeltaker
- Tom Hemming Karlsen Medveileder
- Xiaojun Jiang Medveileder
- Pål Dag Line Medveileder
- Espen Melum Prosjektdeltaker
- Laura Valestrand Doktorgradsstipendiat (finansiert av denne bevilgning)
- Zheng Fei Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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