Personalized Radiation Therapy of Cancer: Tumor Interstitial Fluid Pressure and Peritumoral Interstitial Fluid Flow
- Prosjektnummer
- 2015035
- Ansvarlig person
- Einar K. Rofstad
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 4. Detection and Diagnosis, 5. Treatment Developement
NEI
Intratumor Heterogeneity in Interstitial Fluid Pressure in Cervical and Pancreatic Carcinoma Xenografts.
Transl Oncol 2019 Aug;12(8):1079-1085. Epub 2019 jun 4
PMID: 31174058
DCE-MRI and Quantitative Histology Reveal Enhanced Vessel Maturation but Impaired Perfusion and Increased Hypoxia in Bevacizumab-Treated Cervical Carcinoma.
Int J Radiat Oncol Biol Phys 2019 07 01;104(3):666-676. Epub 2019 mar 8
PMID: 30858145 - Inngår i doktorgradsavhandlingen
Pharmacokinetic analysis of DCE-MRI data of locally advanced cervical carcinoma with the Brix model.
Acta Oncol 2019 Jun;58(6):828-837. Epub 2019 feb 27
PMID: 30810443
Diffusion-Weighted MRI Is Insensitive to Changes in the Tumor Microenvironment Induced by Antiangiogenic Therapy.
Transl Oncol 2018 Oct;11(5):1128-1136. Epub 2018 jul 21
PMID: 30036782 - Inngår i doktorgradsavhandlingen
DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts.
Neoplasia 2018 07;20(7):734-744. Epub 2018 jun 19
PMID: 29886124 - Inngår i doktorgradsavhandlingen
Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation.
Oncotarget 2018 Apr 20;9(30):21036-21051. Epub 2018 apr 20
PMID: 29765518 - Inngår i doktorgradsavhandlingen
DCE-MRI-Derived Measures of Tumor Hypoxia and Interstitial Fluid Pressure Predict Outcomes in Cervical Carcinoma.
Int J Radiat Oncol Biol Phys 2018 Nov 15;102(4):1193-1201. Epub 2018 apr 19
PMID: 29859790
Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer.
Oncotarget 2017 Dec 01;8(62):105682-105691. Epub 2017 nov 11
PMID: 29285283 - Inngår i doktorgradsavhandlingen
DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment.
J Transl Med 2017 Nov 03;15(1):225. Epub 2017 nov 3
PMID: 29100521 - Inngår i doktorgradsavhandlingen
Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts.
Acta Oncol 2017 Dec;56(12):1754-1762. Epub 2017 jun 29
PMID: 28661213 - Inngår i doktorgradsavhandlingen
Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer.
Acta Oncol 2017 May;56(5):675-681. Epub 2017 feb 28
PMID: 28447564
Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts.
Oncotarget 2017 Jul 18;8(29):48060-48074.
PMID: 28624797
Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis.
Oncotarget 2016 Aug 30;7(35):56986-56997.
PMID: 27486768
Cancer stem cells (CSCs), cervical CSCs and targeted therapies.
Oncotarget 2016 Jun 19. Epub 2016 jun 19
PMID: 27343550
Diffusion-weighted and dynamic contrast-enhanced MRI of pancreatic adenocarcinoma xenografts: associations with tumor differentiation and collagen content.
J Transl Med 2016 Jun 07;14(1):161. Epub 2016 jun 7
PMID: 27268062
Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix.
Cancer Lett 2016 Apr 10;373(2):147-55. Epub 2016 jan 29
PMID: 26828134
Early effects of low dose bevacizumab treatment assessed by magnetic resonance imaging.
BMC Cancer 2015;15(1):900. Epub 2015 nov 14
PMID: 26573613
Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix.
BMC Cancer 2015;15():805. Epub 2015 okt 26
PMID: 26502718
Short-term pretreatment DCE-MRI in prediction of outcome in locally advanced cervical cancer.
Radiother Oncol 2015 Jun;115(3):379-85. Epub 2015 mai 18
PMID: 25998804
The tumor microenvironment and its assessment with DCE-MRI and DW-MRI
- Disputert:
- september 2019
- Hovedveileder:
- Einar K Rofstad
- Kjersti Vassmo Lund Prosjektdeltaker
- Lise Mari Klepp Andersen Prosjektdeltaker
- Ruixia Huang Postdoktorstipendiat (annen finansiering)
- Jon-Vidar Gaustad Forsker (annen finansiering)
- Catherine E Sem Wegner Postdoktorstipendiat (annen finansiering)
- Trude Golimo Simonsen Postdoktorstipendiat (annen finansiering)
- Anette Hauge Doktorgradsstipendiat (finansiert av denne bevilgning)
- Einar K Rofstad Prosjektleder
- Kanthi Galappathi Prosjektdeltaker
- Christine Ellingsen Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport