Epigenetic biomarkers in circulating DNA (ctDNA) for early diagnostics and treatment monitoring in breast cancer
- Prosjektnummer
- 2015080
- Ansvarlig person
- Vessela N. Kristensen
- Institusjon
- Akershus universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 4. Detection and Diagnosis, 6. Treatment Evaluation
NEI
No
NEI
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.
Nat Commun 2019 04 15;10(1):1749. Epub 2019 apr 15
PMID: 30988298
Development of high‑resolution melting analysis for ABCB1 promoter methylation: Clinical consequences in breast and ovarian carcinoma.
Oncol Rep 2019 Aug;42(2):763-774. Epub 2019 jun 5
PMID: 31173253
Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations.
Genome Med 2018 11 29;10(1):92. Epub 2018 nov 29
PMID: 30497530
Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis.
Int J Epidemiol 2018 Oct 01. Epub 2018 okt 1
PMID: 30277539
Subtype-specific clinical and prognostic relevance of tumor-expressed F5 and regulatory F5 variants in breast cancer: the CoCaV study.
J Thromb Haemost 2018 Jul;16(7):1347-1356. Epub 2018 jun 12
PMID: 29766637
Enrichment of methylated molecules using enhanced-ice-co-amplification at lower denaturation temperature-PCR (E-ice-COLD-PCR) for the sensitive detection of disease-related hypermethylation.
Epigenomics 2018 05;10(5):525-537. Epub 2018 apr 26
PMID: 29697281
DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival.
Oncotarget 2017 Jan 03;8(1):1074-1082.
PMID: 27911866
DNA methylation at enhancers identifies distinct breast cancer lineages.
Nat Commun 2017 Nov 09;8(1):1379. Epub 2017 nov 9
PMID: 29123100
Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
Nature 2016 Sep 01;537(7618):63-68. Epub 2016 aug 17
PMID: 27533040
Women at high risk of breast cancer: Molecular characteristics, clinical presentation and management.
Breast 2016 Aug;28():136-44. Epub 2016 jun 16
PMID: 27318168
Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing.
Genome Biol 2016 Dec 09;17(1):250. Epub 2016 des 9
PMID: 27931250
A systematic comparison of copy number alterations in four types of female cancer.
BMC Cancer 2016 Nov 22;16(1):913. Epub 2016 nov 22
PMID: 27876019
Determinants of acquired activated protein C resistance and D-dimer in breast cancer.
Thromb Res 2016 Sep;145():78-83. Epub 2016 aug 3
PMID: 27505249
Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer.
Cell Rep 2016 Jul 26;16(4):1166-79. Epub 2016 jul 7
PMID: 27396337
GFRA3 promoter methylation may be associated with decreased postoperative survival in gastric cancer.
BMC Cancer 2016 Mar 16;16():225. Epub 2016 mar 16
PMID: 26984265
Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis.
Mol Oncol 2016 Feb;10(2):330-43. Epub 2015 nov 6
PMID: 26601720
Heterogeneous DNA Methylation Patterns in the GSTP1 Promoter Lead to Discordant Results between Assay Technologies and Impede Its Implementation as Epigenetic Biomarkers in Breast Cancer.
Genes (Basel) 2015;6(3):878-900. Epub 2015 sep 17
PMID: 26393654
DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer.
Clin Epigenetics 2015;7(1):75. Epub 2015 jul 25
PMID: 26213588
Breast-cancer screening--viewpoint of the IARC Working Group.
N Engl J Med 2015 Jun 11;372(24):2353-8. Epub 2015 jun 3
PMID: 26039523
- Zdenko Herceg Prosjektleder
- Jörg Tost Prosjektleder
- Olav Engebråten Prosjektdeltaker
- Bjørn Naume Prosjektdeltaker
- Arnoldo Frigessi Prosjektleder
- Thomas Fleischer Forsker (annen finansiering)
- Grethe Irene Grenaker Alnæs Prosjektleder
- Vessela N. Kristensen Forskningsgruppeleder
- Jovana Klajic Postdoktorstipendiat (finansiert av denne bevilgning)
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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