Development of novel strategies for treating Alzheimer's disease by understanding glial mechanisms for brain waste removal
- Prosjektnummer
- 2016070
- Ansvarlig person
- Erlend Arnulf Nagelhus
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Neurological
- Forskningsaktivitet
- 1. Underpinning
NEI
NEI
Ca2+ Signals in Astrocytes Facilitate Spread of Epileptiform Activity.
Cereb Cortex 2018 Nov 01;28(11):4036-4048.
PMID: 30169757
Human and mouse cortical astrocytes differ in aquaporin-4 polarization toward microvessels.
Glia 2017 Jun;65(6):964-973. Epub 2017 mar 20
PMID: 28317216
Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow.
Proc Natl Acad Sci U S A 2017 Sep 12;114(37):9894-9899. Epub 2017 aug 28
PMID: 28847942
Deletion of Aquaporin-4 Curtails Extracellular Glutamate Elevation in Cortical Spreading Depression in Awake Mice.
Cereb Cortex 2017 Jan 01;27(1):24-33.
PMID: 28365776
Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation.
Mol Cell Neurosci 2016 Dec;77():47-52. Epub 2016 okt 14
PMID: 27751903
Cortical astrogliosis and increased perivascular aquaporin-4 in idiopathic intracranial hypertension.
Brain Res 2016 Aug 01;1644():161-75. Epub 2016 mai 14
PMID: 27188961
Molecular and functional aspects of astrocytes at the brain-blood interface
- Disputert:
- august 2016
- Hovedveileder:
- Erlend Arnulf Nagelhus
- Rune Enger Postdoktorstipendiat (finansiert av denne bevilgning)
- Erlend Arnulf Nagelhus Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport