Gestational diabetes and offspring’s adiposity; A possible role for maternal folate and vitamin B12 status and epigenetics
- Prosjektnummer
- 2016076
- Ansvarlig person
- Kåre I. Birkeland
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Metabolic and Endocrine, Reproductive Health and Childbirth
- Forskningsaktivitet
- 2. Aetiology, 4. Detection and Diagnosis
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Diabetes 2022 Dec 19. Epub 2022 des 19
PMID: 36534481
Insulin and body mass index decrease serum soluble leptin receptor levels in humans.
J Clin Endocrinol Metab 2022 Dec 02. Epub 2022 des 2
PMID: 36459457
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.
Hum Mol Genet 2022 Sep 29;31(19):3377.
PMID: 35220425
Maternal Glucose and LDL-Cholesterol Levels Are Related to Placental Leptin Gene Methylation, and, Together With Nutritional Factors, Largely Explain a Higher Methylation Level Among Ethnic South Asians.
Front Endocrinol (Lausanne) 2021;12():809916. Epub 2021 des 24
PMID: 35002980
Cohort profile: Epigenetics in Pregnancy (EPIPREG) - population-based sample of European and South Asian pregnant women with epigenome-wide DNA methylation (850k) in peripheral blood leukocytes.
PLoS One 2021;16(8):e0256158. Epub 2021 aug 13
PMID: 34388220
Epigenetic signatures associated with maternal body mass index or gestational weight gain: a systematic review.
J Dev Orig Health Dis 2020 Sep 02. Epub 2020 sep 2
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Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight.
Int J Epidemiol 2020 Dec 21. Epub 2020 des 21
PMID: 33347560
Ethnic differences in body mass index trajectories from 18 years to postpartum in a population-based cohort of pregnant women in Norway.
BMJ Open 2019 02 22;9(2):e022640. Epub 2019 feb 22
PMID: 30798304
Phenotypic and genotypic differences between Indian and Scandinavian women with gestational diabetes mellitus.
J Intern Med 2019 Aug;286(2):192-206. Epub 2019 apr 29
PMID: 30919529
Comparison of the associations between non-traditional and traditional indices of adiposity and cardiovascular mortality: an observational study of one million person-years of follow-up.
Int J Obes (Lond) 2019 05;43(5):1082-1092. Epub 2019 mar 29
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Genetic determinants of glucose levels in pregnancy: genetic risk scores analysis and GWAS in the Norwegian STORK cohort.
Eur J Endocrinol 2018 Dec 01;179(6):363-372.
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Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization study.
Am J Clin Nutr 2018 Aug 01;108(2):398-404.
PMID: 29982347
Soluble Leptin Receptor Predicts Insulin Sensitivity and Correlates With Upregulation of Metabolic Pathways in Men.
J Clin Endocrinol Metab 2018 03 01;103(3):1024-1032.
PMID: 29300960
Persistent symptoms in patients with Crohn's disease in remission: An exploratory study on the role of diet.
Scand J Gastroenterol 2017 Nov 23. Epub 2017 nov 23
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Ethnic differences in folic acid supplement use in a population-based cohort of pregnant women in Norway.
BMC Pregnancy Childbirth 2017 May 15;17(1):143. Epub 2017 mai 15
PMID: 28506268
MECHANISMS IN ENDOCRINOLOGY: Epigenetic modifications and gestational diabetes: a systematic review of published literature.
Eur J Endocrinol 2017 May;176(5):R247-R267. Epub 2017 feb 23
PMID: 28232369
Soluble Leptin Receptor and Risk of Gestational Diabetes in a Multiethnic Population: A Prospective Cohort Study.
J Clin Endocrinol Metab 2016 Nov;101(11):4070-4075. Epub 2016 aug 18
PMID: 27537771
Ethnic Differences in Gestational Weight Gain: A Population-Based Cohort Study in Norway.
Matern Child Health J 2016 Jul;20(7):1485-96.
PMID: 26979613
Ethnic differences in postpartum weight retention: a Norwegian cohort study.
BJOG 2016 Apr;123(5):699-708. Epub 2015 feb 25
PMID: 25716276
Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes
Preprint, MedRxiv. https://doi.org/10.1101/2022.11.23.22282639
Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain
Preprint, Research Square. https://www.researchsquare.com/article/rs-2517570/v1
- Teresa Linares Pineda Prosjektdeltaker
- Sonsoles Morcillo Internasjonal samarbeidspartner
- Bonnie Joubert Internasjonal samarbeidspartner
- Stephanie London Internasjonal samarbeidspartner
- Hannah Elliott Internasjonal samarbeidspartner
- Yvonne Böttcher Prosjektdeltaker
- Sindre Lee-Ødegård Prosjektdeltaker
- Anne Karen Jenum Prosjektdeltaker
- Line Sletner Prosjektdeltaker
- Nadia Kiryuschenko Prosjektdeltaker
- Julia O. Opsahl Prosjektdeltaker
- Kåre I. Birkeland Prosjektleder
- Leif Groop Prosjektdeltaker
- Rashmi Prasad Prosjektdeltaker
- Gunn-Helen Øiseth Moen Doktorgradsstipendiat (annen finansiering)
- Elisabeth Qvigstad Prosjektdeltaker
- Christine Sommer Postdoktorstipendiat (finansiert av denne bevilgning)
- Jens Bollerslev Prosjektdeltaker
- Tore Henriksen Prosjektdeltaker
- Borghild Barth-H Roald Prosjektdeltaker
- Marie Cecilie Paasche Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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