Photochemical Strategies Enhancing the Efficacy of Cancer Immunotherapies
- Prosjektnummer
- 2017068
- Ansvarlig person
- Pål Kristian Selbo
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Forskerstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 5. Treatment Developement
NEI
Nei.
NEI
NEI
Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1.
Cells 2021 06 12;10(6). Epub 2021 jun 12
PMID: 34204611
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy.
Biochem Pharmacol 2021 12;194():114837. Epub 2021 nov 12
PMID: 34780750
Light-controlled elimination of PD-L1+ cells.
J Photochem Photobiol B 2021 Dec;225():112355. Epub 2021 nov 7
PMID: 34768077
Photochemical Internalization: Light Paves Way for New Cancer Chemotherapies and Vaccines.
Cancers (Basel) 2020 Jan 09;12(1). Epub 2020 jan 9
PMID: 31936595
Photochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research.
J Clin Med 2020 Feb 14;9(2). Epub 2020 feb 14
PMID: 32075165
High aldehyde dehydrogenase activity does not protect colon cancer cells against TPCS
Photochem Photobiol Sci 2020 Mar 01;19(3):308-312. Epub 2020 feb 28
PMID: 32108197
Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy.
Cancers (Basel) 2020 Feb 11;12(2). Epub 2020 feb 11
PMID: 32053965
Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers.
Front Immunol 2020;11():576756. Epub 2021 jan 8
PMID: 33488576
Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization.
J Clin Med 2019 Dec 26;9(1). Epub 2019 des 26
PMID: 31888091
Photochemical internalization enhances cytosolic release of antibiotic and increases its efficacy against staphylococcal infection.
J Control Release 2018 Aug 10;283():214-222. Epub 2018 jun 5
PMID: 29883696
Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins.
Photochem Photobiol Sci 2018 May 16;17(5):539-551.
PMID: 29565434
Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination.
Front Immunol 2018;9():650. Epub 2018 apr 4
PMID: 29670624
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.
J Exp Clin Cancer Res 2017 Dec 19;36(1):187. Epub 2017 des 19
PMID: 29258566
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance.
Biochem Pharmacol 2017 11 15;144():63-77. Epub 2017 aug 5
PMID: 28784290
Photochemical Internalization of Gemcitabine Is Safe and Effective in Locally Advanced Inoperable Cholangiocarcinoma
The Oncologist, 2022, In press
Photochemical Strategies to Eliminate Cancer Cells
- Disputert:
- desember 2021
- Hovedveileder:
- Pål Kristian Selbo
Mechanisms of Resistance to TPCS2a-Photodynamic Therapy: Implication for Photochemical Internalization
- Disputert:
- november 2017
- Hovedveileder:
- Pål Kristian Selbo
- Andreas John Carl Brech Forsker (annen finansiering)
- Jørgen Wesche Forsker (annen finansiering)
- Judith Jing Wen Wong Doktorgradsstipendiat (annen finansiering)
- Alf Kristian Berg Forsker (annen finansiering)
- Anders Høgset Forsker (annen finansiering)
- Anette Weyergang Forsker (annen finansiering)
- Monika Håkerud Prosjektdeltaker
- Pål Kristian Selbo Prosjektleder
- Pål Johansen Prosjektdeltaker
- Daniel Vallera Prosjektdeltaker
- Michael Rosenblum Prosjektdeltaker
- Cathrine Elisabeth Olsen Prosjektdeltaker
- Judith Wong Doktorgradsstipendiat (annen finansiering)
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport