HUNT biobank - basale biobankfunksjoner

Prosjektnummer: 25053500-1
Ansvarlig person: Kristian Hveem
Institusjon: NTNU, ISM
Prosjektkategori: Nytt infrastrukturtiltak
Helsekategori: Generic Health Relevance
Forskningsaktivitet: 3. Prevention

2010

HUNT biobank - basale biobankfunksjonerSamarbeidsorganet har gitt en årlig driftsstøtte til HUNT biobank for drift av et større lager av biologiske prøver på flytende nitrogen.HUNT biobank flyttet i 2006 inn i et helt nytt, og moderne laboratoriebygg/lager hvor man blant annet har kapasitet til å oppbevare mellom 1,5 - 3 millioner biologiske prøver i til sammen 14 større nitrogentanker. Lagring på flytende nitrogen antas å være spesielt hensiktsmessig da slike lave temperaturer gir den beste holdbarhet av et meget verdifullt historisk materiale. Prosjektet er støttet med 1,5 millioner kr av samarbeidsorganet pr år til følgende: i) innkjøp av flytende nitrogen, ii) serviceavtaler knyttet til drift, og iii) lønnsmidler til 2 avdelingsingeniørstillinger for ivaretakelse og utlevering av biologisk materiale til forskning. Midlene er i sin helhet benyttet til dette formål. 2010 har vært et godt år for HUNT forskningssenter og biobank med stor aktivitet og økende forespørsel etter våre tjenester. HUNT biobank/NTNU er også koordinator i den nasjonale forskningsinfrastrukturen for biobanker, Biobank Norge, som er finansiert med 80 millioner kr. av Norges Forskningsråd for driftsperioden 2011-2013. HUNT biobank er en av to nasjonale biobanker i dette nettverket, og infrastrukturstøtten fra samarbeidsorganet har også i denne sammenhengen vært svært kjærkommen. HUNT biobank lagrer i økende grad biologisk materiale for andre forskergrupper ved NTNU, St.Olavs Hospital og andre nasjonale samarbeidspartnere. Vi oppbevarer også prøver fra truende arter (den såkalte ”Rødlista”) for Vitenskapsmuseet. En rekke forskergrupper har i 2010 stått bak et større antall publikasjoner hvor det er benyttet biologisk materiale fra HUNT biobank.

Vitenskapelige artikler

Wangensteen Teresia, Akselsen Hanne, Holmen Jostein, Undlien Dag, Retterstøl Lars

A Common Haplotype in NAPEPLD Is Associated With Severe Obesity in a Norwegian Population-Based Cohort (the HUNT Study).

Obesity (Silver Spring) 2010 Sep. Epub 2010 sep 30

PMID: 20885390

Heuch Ingrid, Heuch Ivar, Hagen Knut, Zwart John-Anker

Associations between serum lipid levels and chronic low back pain.

Epidemiology 2010 Nov;21(6):837-41.

PMID: 20798637

Pettersen Elin, Skorpen Frank, Kvaløy Kirsti, Midthjell Kristian, Grill Valdemar

Genetic heterogeneity in latent autoimmune diabetes is linked to various degrees of autoimmune activity: results from the Nord-Trøndelag Health Study.

Diabetes 2010 Jan;59(1):302-10. Epub 2009 okt 15

PMID: 19833889

Thorstensen Ketil, Kvitland Mona A, Irgens Wenche Ø, Hveem Kristian, Asberg Arne

Screening for C282Y homozygosity in a Norwegian population (HUNT2): The sensitivity and specificity of transferrin saturation.

Scand J Clin Lab Invest 2010 Apr;70(2):92-7.

PMID: 20073670

Meltzer Helle Margrete, Brantsaeter Anne Lise, Borch-Iohnsen Berit, Ellingsen Dag G, Alexander Jan, Thomassen Yngvar, Stigum Hein, Ydersbond Trond A

Low iron stores are related to higher blood concentrations of manganese, cobalt and cadmium in non-smoking, Norwegian women in the HUNT 2 study.

Environ Res 2010 Jul;110(5):497-504. Epub 2010 apr 8

PMID: 20381026

Wangensteen T, Egeland T, Akselsen H, Holmen J, Undlien D, Retterstøl L

FTO genotype and weight gain in obese and normal weight adults from a Norwegian population based cohort (the HUNT study).

Exp Clin Endocrinol Diabetes 2010 Oct;118(9):649-52. Epub 2010 apr 6

PMID: 20373279

Holmen Oddgeir L, Romundstad Solfrid, Melien Oyvind

Association between the G protein ß3 subunit C825T polymorphism and the occurrence of cardiovascular disease in hypertensives: The Nord-Trøndelag Health Study (HUNT).

Am J Hypertens 2010 Oct;23(10):1121-7. Epub 2010 jun 10

PMID: 20539277

Vengen Inga Thorsen, Dale Ane Cecilie, Wiseth Rune, Midthjell Kristian, Videm Vibeke

Lactoferrin is a novel predictor of fatal ischemic heart disease in diabetes mellitus type 2: long-term follow-up of the HUNT 1 study.

Atherosclerosis 2010 Oct;212(2):614-20. Epub 2010 jun 11

PMID: 20598696

Voight Benjamin F, Scott Laura J, Steinthorsdottir Valgerdur, Morris Andrew P, Dina Christian, Welch Ryan P, Zeggini Eleftheria, Huth Cornelia, Aulchenko Yurii S, Thorleifsson Gudmar, McCulloch Laura J, Ferreira Teresa, Grallert Harald, Amin Najaf, Wu Guanming, Willer Cristen J, Raychaudhuri Soumya, McCarroll Steve A, Langenberg Claudia, Hofmann Oliver M, Dupuis Josée, Qi Lu, Segrè Ayellet V, van Hoek Mandy, Navarro Pau, Ardlie Kristin, Balkau Beverley, Benediktsson Rafn, Bennett Amanda J, Blagieva Roza, Boerwinkle Eric, Bonnycastle Lori L, Bengtsson Boström Kristina, Bravenboer Bert, Bumpstead Suzannah, Burtt Noisël P, Charpentier Guillaume, Chines Peter S, Cornelis Marilyn, Couper David J, Crawford Gabe, Doney Alex S F, Elliott Katherine S, Elliott Amanda L, Erdos Michael R, Fox Caroline S, Franklin Christopher S, Ganser Martha, Gieger Christian, Grarup Niels, Green Todd, Griffin Simon, Groves Christopher J, Guiducci Candace, Hadjadj Samy, Hassanali Neelam, Herder Christian, Isomaa Bo, Jackson Anne U, Johnson Paul R V, Jørgensen Torben, Kao Wen H L, Klopp Norman, Kong Augustine, Kraft Peter, Kuusisto Johanna, Lauritzen Torsten, Li Man, Lieverse Aloysius, Lindgren Cecilia M, Lyssenko Valeriya, Marre Michel, Meitinger Thomas, Midthjell Kristian, Morken Mario A, Narisu Narisu, Nilsson Peter, Owen Katharine R, Payne Felicity, Perry John R B, Petersen Ann-Kristin, Platou Carl, Proença Christine, Prokopenko Inga, Rathmann Wolfgang, Rayner N William, Robertson Neil R, Rocheleau Ghislain, Roden Michael, Sampson Michael J, Saxena Richa, Shields Beverley M, Shrader Peter, Sigurdsson Gunnar, Sparsø Thomas, Strassburger Klaus, Stringham Heather M, Sun Qi, Swift Amy J, Thorand Barbara, Tichet Jean, Tuomi Tiinamaija, van Dam Rob M, van Haeften Timon W, van Herpt Thijs, van Vliet-Ostaptchouk Jana V, Walters G Bragi, Weedon Michael N, Wijmenga Cisca, Witteman Jacqueline, Bergman Richard N, Cauchi Stephane, Collins Francis S, Gloyn Anna L, Gyllensten Ulf, Hansen Torben, Hide Winston A, Hitman Graham A, Hofman Albert, Hunter David J, Hveem Kristian, Laakso Markku, Mohlke Karen L, Morris Andrew D, Palmer Colin N A, Pramstaller Peter P, Rudan Igor, Sijbrands Eric, Stein Lincoln D, Tuomilehto Jaakko, Uitterlinden Andre, Walker Mark, Wareham Nicholas J, Watanabe Richard M, Abecasis Gonçalo R, Boehm Bernhard O, Campbell Harry, Daly Mark J, Hattersley Andrew T, Hu Frank B, Meigs James B, Pankow James S, Pedersen Oluf, Wichmann H-Erich, Barroso Inês, Florez Jose C, Frayling Timothy M, Groop Leif, Sladek Rob, Thorsteinsdottir Unnur, Wilson James F, Illig Thomas, Froguel Philippe, van Duijn Cornelia M, Stefansson Kari, Altshuler David, Boehnke Michael, McCarthy Mark I, PubMed.ItemsChoiceType2[], PubMed.ItemsChoiceType2[]

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.

Nat Genet 2010 Jul;42(7):579-89.

PMID: 20581827

Heid Iris M, Jackson Anne U, Randall Joshua C, Winkler Thomas W, Qi Lu, Steinthorsdottir Valgerdur, Thorleifsson Gudmar, Zillikens M Carola, Speliotes Elizabeth K, Mägi Reedik, Workalemahu Tsegaselassie, White Charles C, Bouatia-Naji Nabila, Harris Tamara B, Berndt Sonja I, Ingelsson Erik, Willer Cristen J, Weedon Michael N, Luan Jian'an, Vedantam Sailaja, Esko Tõnu, Kilpeläinen Tuomas O, Kutalik Zoltán, Li Shengxu, Monda Keri L, Dixon Anna L, Holmes Christopher C, Kaplan Lee M, Liang Liming, Min Josine L, Moffatt Miriam F, Molony Cliona, Nicholson George, Schadt Eric E, Zondervan Krina T, Feitosa Mary F, Ferreira Teresa, Allen Hana Lango, Weyant Robert J, Wheeler Eleanor, Wood Andrew R, PubMed.ItemsChoiceType2[], Estrada Karol, Goddard Michael E, Lettre Guillaume, Mangino Massimo, Nyholt Dale R, Purcell Shaun, Smith Albert Vernon, Visscher Peter M, Yang Jian, McCarroll Steven A, Nemesh James, Voight Benjamin F, Absher Devin, Amin Najaf, Aspelund Thor, Coin Lachlan, Glazer Nicole L, Hayward Caroline, Heard-Costa Nancy L, Hottenga Jouke-Jan, Johansson Asa, Johnson Toby, Kaakinen Marika, Kapur Karen, Ketkar Shamika, Knowles Joshua W, Kraft Peter, Kraja Aldi T, Lamina Claudia, Leitzmann Michael F, McKnight Barbara, Morris Andrew P, Ong Ken K, Perry John R B, Peters Marjolein J, Polasek Ozren, Prokopenko Inga, Rayner Nigel W, Ripatti Samuli, Rivadeneira Fernando, Robertson Neil R, Sanna Serena, Sovio Ulla, Surakka Ida, Teumer Alexander, van Wingerden Sophie, Vitart Veronique, Zhao Jing Hua, Cavalcanti-Proença Christine, Chines Peter S, Fisher Eva, Kulzer Jennifer R, Lecoeur Cecile, Narisu Narisu, Sandholt Camilla, Scott Laura J, Silander Kaisa, Stark Klaus, Tammesoo Mari-Liis, Teslovich Tanya M, Timpson Nicholas John, Watanabe Richard M, Welch Ryan, Chasman Daniel I, Cooper Matthew N, Jansson John-Olov, Kettunen Johannes, Lawrence Robert W, Pellikka Niina, Perola Markus, Vandenput Liesbeth, Alavere Helene, Almgren Peter, Atwood Larry D, Bennett Amanda J, Biffar Reiner, Bonnycastle Lori L, Bornstein Stefan R, Buchanan Thomas A, Campbell Harry, Day Ian N M, Dei Mariano, Dörr Marcus, Elliott Paul, Erdos Michael R, Eriksson Johan G, Freimer Nelson B, Fu Mao, Gaget Stefan, Geus Eco J C, Gjesing Anette P, Grallert Harald, Grässler Jürgen, Groves Christopher J, Guiducci Candace, Hartikainen Anna-Liisa, Hassanali Neelam, Havulinna Aki S, Herzig Karl-Heinz, Hicks Andrew A, Hui Jennie, Igl Wilmar, Jousilahti Pekka, Jula Antti, Kajantie Eero, Kinnunen Leena, Kolcic Ivana, Koskinen Seppo, Kovacs Peter, Kroemer Heyo K, Krzelj Vjekoslav, Kuusisto Johanna, Kvaloy Kirsti, Laitinen Jaana, Lantieri Olivier, Lathrop G Mark, Lokki Marja-Liisa, Luben Robert N, Ludwig Barbara, McArdle Wendy L, McCarthy Anne, Morken Mario A, Nelis Mari, Neville Matt J, Paré Guillaume, Parker Alex N, Peden John F, Pichler Irene, Pietiläinen Kirsi H, Platou Carl G P, Pouta Anneli, Ridderstråle Martin, Samani Nilesh J, Saramies Jouko, Sinisalo Juha, Smit Jan H, Strawbridge Rona J, Stringham Heather M, Swift Amy J, Teder-Laving Maris, Thomson Brian, Usala Gianluca, van Meurs Joyce B J, van Ommen Gert-Jan, Vatin Vincent, Volpato Claudia B, Wallaschofski Henri, Walters G Bragi, Widen Elisabeth, Wild Sarah H, Willemsen Gonneke, Witte Daniel R, Zgaga Lina, Zitting Paavo, Beilby John P, James Alan L, Kähönen Mika, Lehtimäki Terho, Nieminen Markku S, Ohlsson Claes, Palmer Lyle J, Raitakari Olli, Ridker Paul M, Stumvoll Michael, Tönjes Anke, Viikari Jorma, Balkau Beverley, Ben-Shlomo Yoav, Bergman Richard N, Boeing Heiner, Smith George Davey, Ebrahim Shah, Froguel Philippe, Hansen Torben, Hengstenberg Christian, Hveem Kristian, Isomaa Bo, Jørgensen Torben, Karpe Fredrik, Khaw Kay-Tee, Laakso Markku, Lawlor Debbie A, Marre Michel, Meitinger Thomas, Metspalu Andres, Midthjell Kristian, Pedersen Oluf, Salomaa Veikko, Schwarz Peter E H, Tuomi Tiinamaija, Tuomilehto Jaakko, Valle Timo T, Wareham Nicholas J, Arnold Alice M, Beckmann Jacques S, Bergmann Sven, Boerwinkle Eric, Boomsma Dorret I, Caulfield Mark J, Collins Francis S, Eiriksdottir Gudny, Gudnason Vilmundur, Gyllensten Ulf, Hamsten Anders, Hattersley Andrew T, Hofman Albert, Hu Frank B, Illig Thomas, Iribarren Carlos, Jarvelin Marjo-Riitta, Kao W H Linda, Kaprio Jaakko, Launer Lenore J, Munroe Patricia B, Oostra Ben, Penninx Brenda W, Pramstaller Peter P, Psaty Bruce M, Quertermous Thomas, Rissanen Aila, Rudan Igor, Shuldiner Alan R, Soranzo Nicole, Spector Timothy D, Syvanen Ann-Christine, Uda Manuela, Uitterlinden André, Völzke Henry, Vollenweider Peter, Wilson James F, Witteman Jacqueline C, Wright Alan F, Abecasis Gonçalo R, Boehnke Michael, Borecki Ingrid B, Deloukas Panos, Frayling Timothy M, Groop Leif C, Haritunians Talin, Hunter David J, Kaplan Robert C, North Kari E, O'Connell Jeffrey R, Peltonen Leena, Schlessinger David, Strachan David P, Hirschhorn Joel N, Assimes Themistocles L, Wichmann H-Erich, Thorsteinsdottir Unnur, van Duijn Cornelia M, Stefansson Kari, Cupples L Adrienne, Loos Ruth J F, Barroso Inês, McCarthy Mark I, Fox Caroline S, Mohlke Karen L, Lindgren Cecilia M

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Nat Genet 2010 Nov;42(11):949-60. Epub 2010 okt 10

PMID: 20935629

Speliotes Elizabeth K, Willer Cristen J, Berndt Sonja I, Monda Keri L, Thorleifsson Gudmar, Jackson Anne U, Allen Hana Lango, Lindgren Cecilia M, Luan Jian'an, Mägi Reedik, Randall Joshua C, Vedantam Sailaja, Winkler Thomas W, Qi Lu, Workalemahu Tsegaselassie, Heid Iris M, Steinthorsdottir Valgerdur, Stringham Heather M, Weedon Michael N, Wheeler Eleanor, Wood Andrew R, Ferreira Teresa, Weyant Robert J, Segrè Ayellet V, Estrada Karol, Liang Liming, Nemesh James, Park Ju-Hyun, Gustafsson Stefan, Kilpeläinen Tuomas O, Yang Jian, Bouatia-Naji Nabila, Esko Tõnu, Feitosa Mary F, Kutalik Zoltán, Mangino Massimo, Raychaudhuri Soumya, Scherag Andre, Smith Albert Vernon, Welch Ryan, Zhao Jing Hua, Aben Katja K, Absher Devin M, Amin Najaf, Dixon Anna L, Fisher Eva, Glazer Nicole L, Goddard Michael E, Heard-Costa Nancy L, Hoesel Volker, Hottenga Jouke-Jan, Johansson Asa, Johnson Toby, Ketkar Shamika, Lamina Claudia, Li Shengxu, Moffatt Miriam F, Myers Richard H, Narisu Narisu, Perry John R B, Peters Marjolein J, Preuss Michael, Ripatti Samuli, Rivadeneira Fernando, Sandholt Camilla, Scott Laura J, Timpson Nicholas J, Tyrer Jonathan P, van Wingerden Sophie, Watanabe Richard M, White Charles C, Wiklund Fredrik, Barlassina Christina, Chasman Daniel I, Cooper Matthew N, Jansson John-Olov, Lawrence Robert W, Pellikka Niina, Prokopenko Inga, Shi Jianxin, Thiering Elisabeth, Alavere Helene, Alibrandi Maria T S, Almgren Peter, Arnold Alice M, Aspelund Thor, Atwood Larry D, Balkau Beverley, Balmforth Anthony J, Bennett Amanda J, Ben-Shlomo Yoav, Bergman Richard N, Bergmann Sven, Biebermann Heike, Blakemore Alexandra I F, Boes Tanja, Bonnycastle Lori L, Bornstein Stefan R, Brown Morris J, Buchanan Thomas A, Busonero Fabio, Campbell Harry, Cappuccio Francesco P, Cavalcanti-Proença Christine, Chen Yii-Der Ida, Chen Chih-Mei, Chines Peter S, Clarke Robert, Coin Lachlan, Connell John, Day Ian N M, Heijer Martin den, Duan Jubao, Ebrahim Shah, Elliott Paul, Elosua Roberto, Eiriksdottir Gudny, Erdos Michael R, Eriksson Johan G, Facheris Maurizio F, Felix Stephan B, Fischer-Posovszky Pamela, Folsom Aaron R, Friedrich Nele, Freimer Nelson B, Fu Mao, Gaget Stefan, Gejman Pablo V, Geus Eco J C, Gieger Christian, Gjesing Anette P, Goel Anuj, Goyette Philippe, Grallert Harald, Grässler Jürgen, Greenawalt Danielle M, Groves Christopher J, Gudnason Vilmundur, Guiducci Candace, Hartikainen Anna-Liisa, Hassanali Neelam, Hall Alistair S, Havulinna Aki S, Hayward Caroline, Heath Andrew C, Hengstenberg Christian, Hicks Andrew A, Hinney Anke, Hofman Albert, Homuth Georg, Hui Jennie, Igl Wilmar, Iribarren Carlos, Isomaa Bo, Jacobs Kevin B, Jarick Ivonne, Jewell Elizabeth, John Ulrich, Jørgensen Torben, Jousilahti Pekka, Jula Antti, Kaakinen Marika, Kajantie Eero, Kaplan Lee M, Kathiresan Sekar, Kettunen Johannes, Kinnunen Leena, Knowles Joshua W, Kolcic Ivana, König Inke R, Koskinen Seppo, Kovacs Peter, Kuusisto Johanna, Kraft Peter, Kvaløy Kirsti, Laitinen Jaana, Lantieri Olivier, Lanzani Chiara, Launer Lenore J, Lecoeur Cecile, Lehtimäki Terho, Lettre Guillaume, Liu Jianjun, Lokki Marja-Liisa, Lorentzon Mattias, Luben Robert N, Ludwig Barbara, PubMed.ItemsChoiceType2[], Manunta Paolo, Marek Diana, Marre Michel, Martin Nicholas G, McArdle Wendy L, McCarthy Anne, McKnight Barbara, Meitinger Thomas, Melander Olle, Meyre David, Midthjell Kristian, Montgomery Grant W, Morken Mario A, Morris Andrew P, Mulic Rosanda, Ngwa Julius S, Nelis Mari, Neville Matt J, Nyholt Dale R, O'Donnell Christopher J, O'Rahilly Stephen, Ong Ken K, Oostra Ben, Paré Guillaume, Parker Alex N, Perola Markus, Pichler Irene, Pietiläinen Kirsi H, Platou Carl G P, Polasek Ozren, Pouta Anneli, Rafelt Suzanne, Raitakari Olli, Rayner Nigel W, Ridderstråle Martin, Rief Winfried, Ruokonen Aimo, Robertson Neil R, Rzehak Peter, Salomaa Veikko, Sanders Alan R, Sandhu Manjinder S, Sanna Serena, Saramies Jouko, Savolainen Markku J, Scherag Susann, Schipf Sabine, Schreiber Stefan, Schunkert Heribert, Silander Kaisa, Sinisalo Juha, Siscovick David S, Smit Jan H, Soranzo Nicole, Sovio Ulla, Stephens Jonathan, Surakka Ida, Swift Amy J, Tammesoo Mari-Liis, Tardif Jean-Claude, Teder-Laving Maris, Teslovich Tanya M, Thompson John R, Thomson Brian, Tönjes Anke, Tuomi Tiinamaija, van Meurs Joyce B J, van Ommen Gert-Jan, Vatin Vincent, Viikari Jorma, Visvikis-Siest Sophie, Vitart Veronique, Vogel Carla I G, Voight Benjamin F, Waite Lindsay L, Wallaschofski Henri, Walters G Bragi, Widen Elisabeth, Wiegand Susanna, Wild Sarah H, Willemsen Gonneke, Witte Daniel R, Witteman Jacqueline C, Xu Jianfeng, Zhang Qunyuan, Zgaga Lina, Ziegler Andreas, Zitting Paavo, Beilby John P, Farooqi I Sadaf, Hebebrand Johannes, Huikuri Heikki V, James Alan L, Kähönen Mika, Levinson Douglas F, Macciardi Fabio, Nieminen Markku S, Ohlsson Claes, Palmer Lyle J, Ridker Paul M, Stumvoll Michael, Beckmann Jacques S, Boeing Heiner, Boerwinkle Eric, Boomsma Dorret I, Caulfield Mark J, Chanock Stephen J, Collins Francis S, Cupples L Adrienne, Smith George Davey, Erdmann Jeanette, Froguel Philippe, Grönberg Henrik, Gyllensten Ulf, Hall Per, Hansen Torben, Harris Tamara B, Hattersley Andrew T, Hayes Richard B, Heinrich Joachim, Hu Frank B, Hveem Kristian, Illig Thomas, Jarvelin Marjo-Riitta, Kaprio Jaakko, Karpe Fredrik, Khaw Kay-Tee, Kiemeney Lambertus A, Krude Heiko, Laakso Markku, Lawlor Debbie A, Metspalu Andres, Munroe Patricia B, Ouwehand Willem H, Pedersen Oluf, Penninx Brenda W, Peters Annette, Pramstaller Peter P, Quertermous Thomas, Reinehr Thomas, Rissanen Aila, Rudan Igor, Samani Nilesh J, Schwarz Peter E H, Shuldiner Alan R, Spector Timothy D, Tuomilehto Jaakko, Uda Manuela, Uitterlinden André, Valle Timo T, Wabitsch Martin, Waeber Gérard, Wareham Nicholas J, Watkins Hugh, PubMed.ItemsChoiceType2[], Wilson James F, Wright Alan F, Zillikens M Carola, Chatterjee Nilanjan, McCarroll Steven A, Purcell Shaun, Schadt Eric E, Visscher Peter M, Assimes Themistocles L, Borecki Ingrid B, Deloukas Panos, Fox Caroline S, Groop Leif C, Haritunians Talin, Hunter David J, Kaplan Robert C, Mohlke Karen L, O'Connell Jeffrey R, Peltonen Leena, Schlessinger David, Strachan David P, van Duijn Cornelia M, Wichmann H-Erich, Frayling Timothy M, Thorsteinsdottir Unnur, Abecasis Gonçalo R, Barroso Inês, Boehnke Michael, Stefansson Kari, North Kari E, McCarthy Mark I, Hirschhorn Joel N, Ingelsson Erik, Loos Ruth J F

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Nat Genet 2010 Nov;42(11):937-48. Epub 2010 okt 10

PMID: 20935630

Lips Esther H, Gaborieau Valerie, McKay James D, Chabrier Amelie, Hung Rayjean J, Boffetta Paolo, Hashibe Mia, Zaridze David, Szeszenia-Dabrowska Neonilia, Lissowska Jolanta, Rudnai Peter, Fabianova Eleonora, Mates Dana, Bencko Vladimir, Foretova Lenka, Janout Vladimir, Field John K, Liloglou Triantafillos, Xinarianos George, McLaughlin John, Liu Geoffrey, Skorpen Frank, Elvestad Maiken Bratt, Hveem Kristian, Vatten Lars, Study Epic, Benhamou Simone, Lagiou Pagona, Holcátová Ivana, Merletti Franco, Kjaerheim Kristina, Agudo Antonio, Castellsagué Xavier, Macfarlane Tatiana V, Barzan Luigi, Canova Cristina, Lowry Ray, Conway David I, Znaor Ariana, Healy Claire, Curado Maria Paula, Koifman Sergio, Eluf-Neto Jose, Matos Elena, Menezes Ana, Fernandez Leticia, Metspalu Andres, Heath Simon, Lathrop Mark, Brennan Paul

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals.

Int J Epidemiol 2010 Apr;39(2):563-77. Epub 2009 sep 23

PMID: 19776245

Prokunina-Olsson Ludmila, Fu Yi-Ping, Tang Wei, Jacobs Kevin B, Hayes Richard B, Kraft Peter, Berndt Sonja I, Wacholder Sholom, Yu Kai, Hutchinson Amy, Spencer Feigelson Heather, Thun Michael J, Diver W Ryan, Albanes Demetrius, Virtamo Jarmo, Weinstein Stephanie, Schumacher Fredrick R, Cancel-Tassin Geraldine, Cussenot Olivier, Valeri Antoine, Andriole Gerald L, Crawford E David, Haiman Christopher A, Henderson Brian E, Kolonel Laurence, Le Marchand Loic, Siddiq Afshan, Riboli Elio, Travis Ruth, Kaaks Rudolf, Isaacs William B, Isaacs Sarah D, Grönberg Henrik, Wiklund Fredrik, Xu Jianfeng, Vatten Lars J, Hveem Kristian, Kumle Merethe, Tucker Margaret, Hoover Robert N, Fraumeni Joseph F, Hunter David J, Thomas Gilles, Chatterjee Nilanjan, Chanock Stephen J, Yeager Meredith

Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2.

Cancer Epidemiol Biomarkers Prev 2010 May;19(5):1349-55. Epub 2010 apr 20

PMID: 20406958

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