Modeling human disease in mice; DNA repair and epigenetic reprogramming
- Prosjektnummer
- 3a-113
- Ansvarlig person
- Arne Klungland
- Institusjon
- Rikshospitalet HF
- Prosjektkategori
- Fritt forskningsprosjekt
- Helsekategori
- Oncogenesis & Cancer Research
- Forskningsaktivitet
- Frie prosjekter - basalforskning
[Nobel Prize for genetic modification]
Tidsskr Nor Laegeforen 2007 Nov;127(23):3054.
PMID: 18049491
Mutations in the RAD27 and SGS1 genes differentially affect the chronological and replicative lifespan of yeast cells growing on glucose and glycerol.
FEMS Yeast Res 2007 Sep;7(6):848-59. Epub 2007 mai 16
PMID: 17506834
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Nature 2007 May;447(7143):447-52. Epub 2007 apr 22
PMID: 17450122
Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA.
EMBO J 2007 Apr;26(8):2206-17. Epub 2007 mar 29
PMID: 17396151
Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice.
Free Radic Res 2007 Feb;41(2):172-81.
PMID: 17364943
Genome instability and DNA damage accumulation in gene-targeted mice.
Neuroscience 2007 Apr;145(4):1309-17. Epub 2007 jan 9
PMID: 17218062
Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice.
Oncogene 2007 Jun;26(27):4044-8. Epub 2007 jan 8
PMID: 17213818
Repair of methyl lesions in DNA and RNA by oxidative demethylation.
Neuroscience 2007 Apr;145(4):1222-32. Epub 2006 des 18
PMID: 17175108
Oxidative damage to purines in DNA: role of mammalian Ogg1.
DNA Repair (Amst) 2007 Apr;6(4):481-8. Epub 2006 nov 28
PMID: 17127104
A novel splice site mutation in the Cockayne syndrome group A gene in two siblings with Cockayne syndrome.
Neuroscience 2007 Apr;145(4):1397-406. Epub 2006 nov 2
PMID: 17084038
Organ and cell specificity of base excision repair mutants in mice.
Mutat Res 2007 Jan;614(1-2):56-68.
PMID: 16765995
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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