Mechanisms of Toll-like receptor 4 signalling and its regulation
- Prosjektnummer
- 46048000
- Ansvarlig person
- Harald Husebye
- Institusjon
- NTNU, IKM
- Prosjektkategori
- Forskerstipend 2011
- Helsekategori
- Inflammatory and Immune System
- Forskningsaktivitet
- 1. Underpinning
TLR3 mediates release of IL-1ß and cell death in keratinocytes in a caspase-4 dependent manner.
J Dermatol Sci 2013 Oct;72(1):45-53. Epub 2013 jun 12
PMID: 23845419
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation.
Nat Commun 2012;3():707. Epub 2012 feb 28
PMID: 22426228
Mechanisms behind toll-like receptor 4 (TLR4) signaling
Winter school 2012 on innate immunity and synthetic biology, March 21-23, Pokljuka, Sloveina.
Mechanisms behind TLR4 induced IFN-ß signaling.
5th NorMIC Meeting. October 25-26, 2012. Bergen.
Frap study of TLR4 dynamics
5th NorMIC Meeting. October 25-26, 2012. Bergen.
The small GTPase Rab11a is involved in LPS induced IFN-ß production
Konferanse, Deconding Innate Immunity, Riva del Garda, Italy, May 4-7, 2011
The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes
NBS møte Storlien March 31 2011
The Rab11a GTPase regulates TLR4 signaling from the phagosome
Konferanse, Toll2011 Deconding Innate Immunity, Riva del Garda, Italy, May 4-7, 2011
The small GTPase Rab11a is involved in LPS induced IFN-ß production
Konferanse, ISB retreat, Fort Worden, Washington, September 14-15, 2011
Dynamics of TLR4 and its adaptor protein TRAM
Konferanse, NorMIC Annual Meeting October 20-21, 2011
The Rab11a GTPase Controls TLR4 - induced activation of interferon regulatory factor-3 on phagosomes
Konferanse, NorMIC Annual Meeting October 20-21, 2011
- Harald Husebye Prosjektleder
- Terje Espevik Forskningsgruppeleder
- Kristian K. Starheim Postdoktorstipendiat
- Astrid Skjesol Postdoktorstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Helse Midt-Norge RHF - Samarbeidsorganet og FFU