PI3K Inhibitors in Basal Like Breast Cancer Evaluation of Targeted Drugs by Molecular MR Spectroscopy
- Prosjektnummer
- 46056655
- Ansvarlig person
- Siver Moestue
- Institusjon
- NTNU, ISB
- Prosjektkategori
- Helse og rehab 2012
- Helsekategori
- Cancer
- Forskningsaktivitet
- 6. Treatment Evaluation
Estrogen Receptor a Promotes Breast Cancer by Reprogramming Choline Metabolism.
Cancer Res 2016 Oct 01;76(19):5634-5646. Epub 2016 jul 25
PMID: 27457520
Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model.
BMC Cancer 2016 Mar 07;16():191. Epub 2016 mar 7
PMID: 26951085
Anti-angiogenic therapy affects the relationship between tumor vascular structure and function: A correlation study between micro-computed tomography angiography and dynamic contrast enhanced MRI.
Magn Reson Med 2017 Oct;78(4):1513-1522. Epub 2016 nov 25
PMID: 27888545
In vivo ³¹P magnetic resonance spectroscopic imaging (MRSI) for metabolic profiling of human breast cancer xenografts.
J Magn Reson Imaging 2015 Mar;41(3):601-9. Epub 2014 feb 14
PMID: 24532410
MRI reveals the in vivo cellular and vascular response to BEZ235 in ovarian cancer xenografts with different PI3-kinase pathway activity.
Br J Cancer 2015 Feb 3;112(3):504-13. Epub 2014 des 23
PMID: 25535727
Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer.
Breast Cancer Res 2013 Feb 28;15(1):R16. Epub 2013 feb 28
PMID: 23448424
Quantitative (31)P HR-MAS MR spectroscopy for detection of response to PI3K/mTOR inhibition in breast cancer xenografts.
Magn Reson Med 2014 Jun;71(6):1973-81. Epub 2013 jul 22
PMID: 23878023
Evaluation of metabolic biomarkers associated to PI3K inhibition in breast cancer xenografts using HR MAS MRS
(Abstract) ISMRM Multimodal Cancer Imaging Workshop 2013
Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
ISMRM Multimodal Cancer Imaging Workshop 2013
Quantitative 31P MRS stratifies treatment response to a PI3K/mTOR inhibitor in two distinct breast cancer xenografts
(Abstract) ISMRM Multimodal Cancer Imaging Workshop 2013
Interplay of Choline Metabolites and Genes in Patient-Derived Breast Cancer Xenografts
(Abstract) ISMRM 21st annual scientific meeting 2013.[Oral presentation] Received the Summa Cum Laude award.
Cytosolic phospholipase A2 (cPLA2) as a therapeutic target in basal-like breast cancer
(Abstract) San Antonio Breast Cancer Symposium 2013
Metabolic responses to VEGF inhibition in patient-derived breast cancer xenografts
Abstract, EACR 2012
Evaluation of metabolic biomarkers associated to PI3K inhibition in breast cancer xenografts using HR MAS MRS
Abstract, MedIm National PhD Conference 2012
Development and application of phosphorus MR techniques for diagnostic, prognostic, and therapeutic assessment of cancer
- Disputert:
- mai 2014
- Hovedveileder:
- Tone F. Bathen
- Siver Andreas Moestue Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Helse Midt-Norge RHF - Samarbeidsorganet og FFU