Molecular mechanisms of exercise as novel therapies for heart failure
- Prosjektnummer
- 46056916
- Ansvarlig person
- Jose Bianco Nascimento Moreira
- Institusjon
- NTNU, ISB
- Prosjektkategori
- Postdoc-stipend 2015
- Helsekategori
- Cardiovascular, Musculoskeletal
- Forskningsaktivitet
- 1. Underpinning, 5. Treatment Developement
This was a translational project that provided important contributions for the field of molecular medicine, discovering novel mechanisms underlying the benefits of physical activity and highlighting their potential as therapeutic drug targets. The new mechanisms discovered in this project, as well as its potential future consequences, will hopefully contribute to new medical treatments, in form of improved therapeutics to treat cardiovascular and muscular disorders.
Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity.
Sci Rep 2018 Dec 11;8(1):17772. Epub 2018 des 11
PMID: 30538258
Exercise prevents impaired autophagy and proteostasis in a model of neurogenic myopathy.
Sci Rep 2018 Aug 07;8(1):11818. Epub 2018 aug 7
PMID: 30087400
Role of KATP Channels in Beneficial Effects of Exercise in Ischemic Heart Failure.
Med Sci Sports Exerc 2015 Dec;47(12):2504-12.
PMID: 26057940
Deletion of Kinin B2 Receptor Alters Muscle Metabolism and Exercise Performance.
PLoS One 2015;10(8):e0134844. Epub 2015 aug 24
PMID: 26302153
- Simone Fenk Prosjektdeltaker
- Ulrik Wisløff Forskningsgruppeleder
- Jose Bianco Nascimento Moreira Prosjektleder
- Martin Rainer Wohlwend Doktorgradsstipendiat
- Ingrid Åmellem Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Helse Midt-Norge RHF - Samarbeidsorganet og FFU