Biomarkers in preclinical Parkinson's Disease
- Prosjektnummer
- 46060906
- Ansvarlig person
- Jan Aasly
- Institusjon
- NTNU, INM
- Prosjektkategori
- Flerårig prosjekt 2011-SO
- Helsekategori
- Neurological
- Forskningsaktivitet
- 2. Aetiology, 4. Detection and Diagnosis
DCTN1 p.K56R in progressive supranuclear palsy.
Parkinsonism Relat Disord 2016 Jul;28():56-61. Epub 2016 apr 23
PMID: 27132499
DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study.
Lancet Neurol 2016 Nov;15(12):1248-1256. Epub 2016 sep 28
PMID: 27692902
Arm swing as a potential new prodromal marker of Parkinson's disease.
Mov Disord 2016 Oct;31(10):1527-1534.
PMID: 27430880
CSF Nrf2 and HSPA8 in Parkinson's disease patients with and without LRRK2 gene mutations.
J Neural Transm (Vienna) 2016 Mar;123(3):179-87. Epub 2015 nov 3
PMID: 26526034
Parkinson's disease, genetic variability and the Faroe Islands.
Parkinsonism Relat Disord 2015 Jan;21(1):75-8. Epub 2014 nov 4
PMID: 25466404
Novel LRRK2 mutations in Parkinsonism.
Parkinsonism Relat Disord 2015 Sep;21(9):1119-21. Epub 2015 jul 18
PMID: 26213354
Genetic variability of the retromer cargo recognition complex in parkinsonism.
Mov Disord 2015 Apr;30(4):580-4. Epub 2014 des 5
PMID: 25475142
DNAJC13 genetic variants in parkinsonism.
Mov Disord 2015 Feb;30(2):273-8. Epub 2014 nov 12
PMID: 25393719
Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease.
Neurology 2014 Nov 18;83(21):1906-13. Epub 2014 okt 17
PMID: 25326098
Elevated levels of cerebrospinal fluid a-synuclein oligomers in healthy asymptomatic LRRK2 mutation carriers.
Front Aging Neurosci 2014;6():248. Epub 2014 sep 25
PMID: 25309429
Michael J. Fox Foundation LRRK2 Consortium: geographical differences in returning genetic research data to study participants.
Genet Med 2014 Aug;16(8):644-5.
PMID: 25093570
LRRK2 parkinsonism in Tunisia and Norway: a comparative analysis of disease penetrance.
Neurology 2014 Aug 5;83(6):568-9. Epub 2014 jul 9
PMID: 25008396
Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.
Glia 2014 Jul;62(7):1075-92. Epub 2014 mar 20
PMID: 24652679
Alpha-synuclein repeat variants and survival in Parkinson's disease.
Mov Disord 2014 Jul;29(8):1053-7. Epub 2014 feb 27
PMID: 24578302
DNAJC13 mutations in Parkinson disease.
Hum Mol Genet 2014 Apr 1;23(7):1794-801. Epub 2013 nov 11
PMID: 24218364
Cheek cell-derived a-synuclein and DJ-1 do not differentiate Parkinson's disease from control.
Neurobiol Aging 2014 Feb;35(2):418-20. Epub 2013 sep 13
PMID: 24041968
Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants.
Neurobiol Aging 2014 Jan;35(1):266.e5-14. Epub 2013 aug 17
PMID: 23962496
Olfactory dysfunction in sporadic Parkinson's Disease and LRRK2 carriers.
Acta Neurol Scand 2014 May;129(5):300-6. Epub 2013 aug 13
PMID: 23937295
Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease.
Brain 2013 Oct;136(Pt 10):3038-50. Epub 2013 sep 2
PMID: 24000005
Found in transcription: accurate Parkinson's disease classification in peripheral blood.
J Parkinsons Dis 2013;3(1):19-29.
PMID: 23938308
Population-specific frequencies for LRRK2 susceptibility variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium.
Mov Disord 2013 Oct;28(12):1740-4. Epub 2013 aug 2
PMID: 23913756
Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations.
Parkinsonism Relat Disord 2013 Oct;19(10):869-77. Epub 2013 jun 17
PMID: 23787135
Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease.
Mov Disord 2013 Jun;28(6):811-3. Epub 2013 mar 1
PMID: 23457019
STX6 rs1411478 is not associated with increased risk of Parkinson's disease.
Parkinsonism Relat Disord 2013 May;19(5):563-5. Epub 2013 feb 14
PMID: 23415606
Cerebrospinal fluid amyloid ß and tau in LRRK2 mutation carriers.
Neurology 2012 Jan;78(1):55-61. Epub 2011 des 14
PMID: 22170881
- Karl Emil Gustavsson Doktorgradsstipendiat
- Jan Aasly Prosjektleder
- Emil Gustavsson Doktorgradsstipendiat
- Krisztina Johansen Postdoktorstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Helse Midt-Norge RHF - Samarbeidsorganet og FFU