Eksperimentell terapi og biologiske prinsipper relatert til hjernesvulsters invasjon
- Prosjektnummer
- 911099
- Ansvarlig person
- Rolf Bjerkvig
- Institusjon
- Universitetet i Bergen
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Oncogenesis & Cancer Research
- Forskningsaktivitet
- Translasjonsforskning
Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres.
Nucleic Acids Res 2007;35(21):7267-78. Epub 2007 okt 24
PMID: 17959650
Lymphangiogenesis in colorectal cancer--prognostic and therapeutic aspects.
Int J Cancer 2007 Oct;121(7):1401-9.
PMID: 17640040
Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats.
J Neurooncol 2007 Nov;85(2):191-202. Epub 2007 jun 8
PMID: 17557137
Cancer initiation and progression: involvement of stem cells and the microenvironment.
Biochim Biophys Acta 2007 Jun;1775(2):283-97. Epub 2007 feb 9
PMID: 17374555
Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors.
BMC Cancer 2007;7():23. Epub 2007 jan 30
PMID: 17263869
Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery.
J Neurooncol 2007 Mar;82(1):1-10. Epub 2006 sep 6
PMID: 16955221
NG2 expression regulates vascular morphology and function in human brain tumours.
Neuroimage 2006 Feb;29(3):965-76. Epub 2005 okt 25
PMID: 16253523
Antitumor efficacy improved by local delivery of species-specific endostatin.
J Neurosurg 2006 Jan;104(1):118-28.
PMID: 16509155
Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1.
Neuro Oncol 2006 Apr;8(2):96-108. Epub 2006 mar 2
PMID: 16533756
Inhibition of medulloblastoma cell invasion by Slit.
Oncogene 2006 Aug;25(37):5103-12. Epub 2006 apr 24
PMID: 16636676
Adeno-associated virus (AAV) serotypes 2, 4 and 5 display similar transduction profiles and penetrate solid tumor tissue in models of human glioma.
J Gene Med 2006 Sep;8(9):1131-40.
PMID: 16810631
Cell therapies for glioblastoma.
Expert Opin Biol Ther 2006 Aug;6(8):739-49.
PMID: 16856796
Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation.
Neuropathol Appl Neurobiol 2006 Aug;32(4):419-27.
PMID: 16866987
Promyelocytic leukemia nuclear bodies are predetermined processing sites for damaged DNA.
J Cell Sci 2006 Aug;119(Pt 16):3284-95. Epub 2006 jul 25
PMID: 16868026
Protein disulfide isomerase expression is related to the invasive properties of malignant glioma.
Cancer Res 2006 Oct;66(20):9895-902.
PMID: 17047051
Angiogenesis-independent tumor growth mediated by stem-like cancer cells.
Proc Natl Acad Sci U S A 2006 Oct;103(44):16466-71. Epub 2006 okt 20
PMID: 17056721
Widespread dispersion of adeno-associated virus serotype 1 and adeno-associated virus serotype 6 vectors in the rat central nervous system and in human glioblastoma multiforme xenografts.
Hum Gene Ther 2005 Mar;16(3):381-92.
PMID: 15812233
Distribution patterns of the anti-angiogenic protein ADAMTS-1 during rat development.
Acta Histochem 2005;107(2):121-31.
PMID: 15878613
The brain slice chamber, a novel variation of the Boyden Chamber Assay, allows time-dependent quantification of glioma invasion into mammalian brain in vitro.
J Neurooncol 2005 May;73(1):9-18.
PMID: 15933811
Opinion: the origin of the cancer stem cell: current controversies and new insights.
Nat Rev Cancer 2005 Nov;5(11):899-904.
PMID: 16327766
Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival.
Cancer Res 2004 Mar;64(6):2105-12.
PMID: 15026350
Cryopreservation of alginate-encapsulated recombinant cells for antiangiogenic therapy.
Cell Transplant 2004;13(1):35-44.
PMID: 15040603
Evidence for a secreted chemorepellent that directs glioma cell invasion.
J Neurobiol 2004 Jul;60(1):71-88.
PMID: 15188274
PML-nuclear bodies accumulate DNA in response to polyomavirus BK and simian virus 40 replication.
Exp Cell Res 2004 Aug;298(1):58-73.
PMID: 15242762
Invasion and Metastasis. In. Russel&Rubinsteins Pathology of Tumours of the Nervous System, 7th Edition, Edvard Arnold Publisher
2007
Invasion and Metastasis
Russel&Rubinsteins Pathology of Tumours of the Nervous System, 7th Edition, Edvard Arnold Publishers, M. Rosenblum, DD. Bigner and R.E. Mc Lendon eds.
Local delivery of endostatin can terminate brain tumor development
American Association for Cancer Research, Proceedings 2004
Proteins Differentially Expressed in Invasive and Angiogenic Glioblastoma Phenotypes.
American Association for Cancer Research, Proceedings, 2004.
Angiogenesis-independen growth mediated by cancer stem cells.
Neuro Oncology, November 2004
Vondarta hjernesvulstar og nye behandlingsstrategiar
- Disputert:
- juni 2007
- Hovedveileder:
- Frits Thorsen
Kreftstamceller og angiogenese i hjernekreft – biologiske mekanismer ved kreftprogresjon
- Disputert:
- februar 2007
- Hovedveileder:
- Per Øyvind Enger
The NG2 proteoglycan. Functional and Therapeutic Implications for Human Brain Tumours
- Disputert:
- mai 2006
- Hovedveileder:
- Rolf Bjerkvig
Studies on viral gene transfer and angiogenesis inhibition in experimental glioma models
- Disputert:
- november 2006
- Hovedveileder:
- Rolf Bjerkvig
Malignant brain tumours. Biological mechanisms and experimental therapies
- Disputert:
- februar 2005
- Hovedveileder:
- Rolf Bjerkvig
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest