Cancer thyreoideae - Molekylærbiologi og klinikk
- Prosjektnummer
- 911223
- Ansvarlig person
- Jan Erik Varhaug
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Cancer
- Forskningsaktivitet
- 5. Treatment Developement
Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas.
BMC Cancer 2009;9():425. Epub 2009 des 8
PMID: 19968886
Composition and biological significance of the human Nalpha-terminal acetyltransferases.
BMC Proc 2009;3 Suppl 6():S3. Epub 2009 aug 4
PMID: 19660096
A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1).
BMC Biochem 2009;10():15. Epub 2009 mai 29
PMID: 19480662
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans.
Proc Natl Acad Sci U S A 2009 May;106(20):8157-62. Epub 2009 mai 6
PMID: 19420222
Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization.
Mol Cell Biol 2009 Jul;29(13):3569-81. Epub 2009 apr 27
PMID: 19398576
Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity.
J Biol Chem 2009 Nov;284(45):31122-9. Epub 2009 sep 10
PMID: 19744929
A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates.
BMC Proc 2009;3 Suppl 6():S2. Epub 2009 aug 4
PMID: 19660095
Protein N-terminal acetylation: NAT 2007-2008 Symposia.
BMC Proc 2009;3 Suppl 6():S1. Epub 2009 aug 4
PMID: 19660094
The protein Nalpha-terminal acetyltransferase hNaa10p (hArd1) is phosphorylated in HEK293 cells.
BMC Res Notes 2009;2():32. Epub 2009 mar 2
PMID: 19284711
The protein acetyltransferase ARD1: a novel cancer drug target?
Curr Cancer Drug Targets 2008 Nov;8(7):545-53.
PMID: 18991565
Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression.
Biochem J 2008 Oct;415(2):325-31.
PMID: 18570629
Nuclear localisation of endogenous SUMO-1-modified PDGF-C in human thyroid tissue and cell lines.
Exp Cell Res 2006 Apr;312(6):782-95. Epub 2006 jan 26
PMID: 16443219
Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex.
Gene 2006 Apr;371(2):291-5. Epub 2006 feb 28
PMID: 16507339
Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex.
Oncogene 2006 Jul;25(31):4350-60. Epub 2006 mar 6
PMID: 16518407
Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase.
BMC Biochem 2006;7():13. Epub 2006 apr 25
PMID: 16638120
Gene expression in poorly differentiated papillary thyroid carcinomas.
Thyroid 2006 Feb;16(2):161-75.
PMID: 16676402
Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.
Biochem J 2005 Mar;386(Pt 3):433-43.
PMID: 15496142
Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms.
Thyroid 2005 Oct;15(10):1131-6.
PMID: 16279846
Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family.
FEBS J 2005 Nov;272(22):5723-41.
PMID: 16279938
Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha.
FEBS Lett 2005 Nov;579(28):6428-32. Epub 2005 nov 2
PMID: 16288748
The human protein N-terminal acetyltransferase A (hNatA) is a potential thyroid cancer drug target
World Congress on Thyroid Cancer P07. www.thyroid2009.ca
A novel candidate road to drug treatment of papillary thyroid carcinoma?
World J Surg 2009:83, Suppl 1
Cancer thyreoiodeae; et translasjonsprosjekt
Norsk Kir Forening Vitenskapelige forhandl 2009
Thyroid cancer: Molecular biology and clinical aspects
In: Molecular carcinogenesis and the molecular biology of human cancer. Eds: Warshawsky D, Landolph JR. CRC Press 2006
Characterization of a processed gene duplicate, hARD2, encoding a novel human protein acetyltransferase interacting with NATH an
Oral presentation, Bergen Conference on Cancer Research, 2005
Expression of NATH and hARD1 proteins in thyroid neoplasms.
Oral presentation, Bergen Conference on Cancer Research, 2005
NATH and hARD1, components of the human NatA protein N-alpha-acetyltransferase complex: characterization of cellular function
- Disputert:
- februar 2006
- Hovedveileder:
- Jan Erik Varhaug
Platelet-derived growth factor C: Structural analysis and endogenous intracellular expression with special reference to human th
- Disputert:
- mai 2005
- Hovedveileder:
- Jan Erik Varhaug
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest