Klinisk kreftforskning med translasjonsstudier av molekylære markører for terapirespons.
- Prosjektnummer
- 911230
- Ansvarlig person
- Olav Dahl
- Institusjon
- Universitetet i Bergen
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Cancer
- Forskningsaktivitet
- 5. Treatment Developement
Fibroblast growth factor 2--a predictor of outcome for patients irradiated for stage II-III non-small-cell lung cancer.
Int J Radiat Oncol Biol Phys 2012 Jan;82(1):442-7. Epub 2010 okt 14
PMID: 20950963
The prognostic impact of tumor cell expression of estrogen receptor-a, progesterone receptor, and androgen receptor in patients irradiated for nonsmall cell lung cancer.
Cancer 2012 Jan;118(1):157-63. Epub 2011 jun 28
PMID: 21713768
High-dose chemotherapy with autologous stem cell support in patients with metastatic non-seminomatous testicular cancer - a report from the Swedish Norwegian Testicular Cancer Group (SWENOTECA).
Acta Oncol 2012 Feb;51(2):168-76. Epub 2011 des 19
PMID: 22175254
Testicular germ cell tumours - still many challenges.
Acta Oncol 2012 Feb;51(2):147-50.
PMID: 22263970
Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer.
Br J Cancer 2012 Nov;107(11):1833-9.
PMID: 23169336
Gene variations in sex hormone pathways and the risk of testicular germ cell tumour: a case-parent triad study in a Norwegian-Swedish population.
Hum Reprod 2012 May;27(5):1525-35. Epub 2012 mar 8
PMID: 22402210
Chemoradiotherapy of anal carcinoma: survival and recurrence in an unselected national cohort.
Int J Radiat Oncol Biol Phys 2012 Jun;83(2):e173-80. Epub 2012 mar 19
PMID: 22436791
Expression of DSG1 and DSC1 are prognostic markers in anal carcinoma patients.
Br J Cancer 2012 Feb;106(4):756-62.
PMID: 22333708
Long-term survival data of triple modality treatment of stage IIB-III-IVA cervical cancer with the combination of radiotherapy, chemotherapy and hyperthermia - an update.
Int J Hyperthermia 2012;28(6):549-53. Epub 2012 jul 13
PMID: 22788973
Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer.
Br J Cancer 2012 Nov;107(10):1684-91. Epub 2012 okt 25
PMID: 23099809
Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: the NORDIC-VII study.
J Clin Oncol 2012 May;30(15):1755-62. Epub 2012 apr 2
PMID: 22473155
MicroRNA-15b is induced with E2F-controlled genes in HPV-related cancer.
Br J Cancer 2011 Nov;105(11):1719-25. Epub 2011 nov 1
PMID: 22045185
Prognostic impact of erythropoietin expression and erythropoietin receptor expression on locoregional control and survival of patients irradiated for stage II/III non-small-cell lung cancer.
Int J Radiat Oncol Biol Phys 2011 Jun;80(2):499-505. Epub 2010 jun 18
PMID: 20646855
Benefit from B-lymphocyte depletion using the anti-CD20 antibody rituximab in chronic fatigue syndrome. A double-blind and placebo-controlled study.
PLoS One 2011;6(10):e26358. Epub 2011 okt 19
PMID: 22039471
A study of coping in long-term testicular cancer survivors.
Psychol Health Med 2010 Mar;15(2):146-58.
PMID: 20391232
Late side effects and quality of life after radiotherapy for rectal cancer.
Int J Radiat Oncol Biol Phys 2010 Mar;76(4):1005-11. Epub 2009 jun 18
PMID: 19540058
Prognostic impact of VEGF and VEGF receptor 1 (FLT1) expression in patients irradiated for stage II/III non-small cell lung cancer (NSCLC).
Strahlenther Onkol 2010 Jun;186(6):307-14. Epub 2010 apr 26
PMID: 20437013
Paternity and testicular function among testicular cancer survivors treated with two to four cycles of cisplatin-based chemotherapy.
Eur Urol 2010 Jul;58(1):134-40. Epub 2010 apr 2
PMID: 20395037
Regional trends in prostate cancer incidence, treatment with curative intent and mortality in Norway 1980-2007.
Cancer Epidemiol 2010 Aug;34(4):359-67. Epub 2010 jun 2
PMID: 20627840
A controlled study of risk factors for disease and current problems in long-term testicular cancer survivors.
J Cancer Surviv 2010 Sep;4(3):256-65. Epub 2010 jun 24
PMID: 20574815
Long-term follow-up after risk-adapted treatment in clinical stage 1 (CS1) nonseminomatous germ-cell testicular cancer (NSGCT) implementing adjuvant CVB chemotherapy. A SWENOTECA study.
Ann Oncol 2010 Sep;21(9):1858-63. Epub 2010 feb 8
PMID: 20142410
Cardiovascular risk factors and morbidity in long-term survivors of testicular cancer: a 20-year follow-up study.
J Clin Oncol 2010 Oct;28(30):4649-57. Epub 2010 sep 20
PMID: 20855830
Prognostic factors in patients with metastatic germ cell tumors who experienced treatment failure with cisplatin-based first-line chemotherapy.
J Clin Oncol 2010 Nov;28(33):4906-11. Epub 2010 okt 18
PMID: 20956623
Alternative cyclin D1 splice forms differentially regulate the DNA damage response.
Cancer Res 2010 Nov;70(21):8802-11. Epub 2010 okt 12
PMID: 20940395
Fear of recurrence in long-term testicular cancer survivors.
Psychooncology 2009 Jun;18(6):580-8.
PMID: 18855944
Topographical distribution of choroidal naevi in the ocular fundus.
Eye (Lond) 2009 Aug;23(8):1685-90. Epub 2008 nov 28
PMID: 19039331
Rectal cancer with macroscopic peritoneal involvement--clinical challenges and consequences.
Colorectal Dis 2009 Oct;11(8):838-44. Epub 2008 okt 1
PMID: 19175632
Kinetics study on markers of the immune system by gene expression profiling of an in vivo heated tumor.
Int J Hyperthermia 2009 Feb;25(1):41-6.
PMID: 19219699
Final results of a randomised phase III study on adjuvant chemotherapy with 5 FU and levamisol in colon and rectum cancer stage II and III by the Norwegian Gastrointestinal Cancer Group.
Acta Oncol 2009;48(3):368-76.
PMID: 19242829
Follow up your unexpected clinical observations!
Acta Oncol 2009;48(3):325-7.
PMID: 19294540
Utilisation of specialist care in patients with incurable rectal cancer. a population-based study from Western Norway.
Acta Oncol 2009;48(3):377-84.
PMID: 19294541
Risk-adapted treatment in clinical stage I nonseminomatous germ cell testicular cancer: the SWENOTECA management program.
J Clin Oncol 2009 May;27(13):2122-8. Epub 2009 mar 23
PMID: 19307506
Duration of symptoms, stage at diagnosis and relative survival in colon and rectal cancer.
Eur J Cancer 2009 Sep;45(13):2383-90. Epub 2009 apr 6
PMID: 19356923
The personality trait of neuroticism is strongly associated with long-term morbidity in testicular cancer survivors.
Acta Oncol 2009;48(6):842-9.
PMID: 19412812
Pulmonary function in long-term survivors of testicular cancer.
J Clin Oncol 2009 Jun;27(17):2779-86. Epub 2009 mai 4
PMID: 19414680
Outcome in intermediate or high risk prostate cancer patients receiving radiation dose and hormone therapy.
Acta Oncol 2009;48(6):874-81.
PMID: 19488886
Topography of solitary congenital hypertrophy of the retinal pigment epithelium in the ocular fundus.
Acta Ophthalmol 2009 Nov;87(8):921-2.
PMID: 19604161
Hyperthermia as an adjuvant to radiation therapy of recurrent or metastatic malignant melanoma. A multicentre randomized trial by the European Society for Hyperthermic Oncology. 1996.
Int J Hyperthermia 2009 Aug;25(5):323-34.
PMID: 19670088
Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis.
Br J Cancer 2009 Oct;101(8):1282-9. Epub 2009 sep 22
PMID: 19773751
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.
Nat Genet 2009 Nov;41(11):1238-42. Epub 2009 okt 4
PMID: 19801978
Cancer therapy targeted at cellular signal transduction mechanisms: strategies, clinical results, and unresolved issues.
Eur J Pharmacol 2009 Dec;625(1-3):6-22. Epub 2009 okt 18
PMID: 19836383
cDNA microarray analysis of serially sampled cervical cancer specimens from patients treated with thermochemoradiotherapy.
Int J Radiat Oncol Biol Phys 2009 Dec;75(5):1562-9.
PMID: 19931738
Observational study of prevalence of long-term Raynaud-like phenomena and neurological side effects in testicular cancer survivors.
J Natl Cancer Inst 2009 Dec;101(24):1682-95.
PMID: 19940282
Posterior uveal melanoma treated with I-125 brachytherapy or primary enucleation.
Eye 2008 Nov;22(11):1398-403. Epub 2007 jun 22
PMID: 17585309
Incidence of iris melanoma in western Norway.
Acta Ophthalmol 2008 Feb;86(1):116-7. Epub 2007 aug 28
PMID: 17725612
Posterior uveal melanoma. Distribution of the sites of origin and patterns of tumour extent in the ocular fundus.
Br J Ophthalmol 2008 Jun;92(6):751-6.
PMID: 18523080
Palliative surgery for rectal cancer in a national cohort.
Colorectal Dis 2008 May;10(4):336-43. Epub 2007 sep 13
PMID: 17868410
Late gastrointestinal morbidity after three-dimensional conformal radiation therapy for prostate cancer fades with time in contrast to genitourinary morbidity.
Int J Radiat Oncol Biol Phys 2008 Apr;70(5):1478-86. Epub 2007 des 3
PMID: 18060703
[Anal cancer]
Tidsskr Nor Laegeforen 2008 Jan;128(2):198-200.
PMID: 18202733
Current status of antivascular therapy and targeted treatment in the clinic.
Int J Hyperthermia 2008 Feb;24(1):97-110.
PMID: 18214773
Hyperthermia improves the antitumour effect of metronomic cyclophosphamide in a rat transplantable brain tumour.
Radiother Oncol 2008 Mar;86(3):435-42. Epub 2008 mar 4
PMID: 18313158
Gene expression reveals two distinct groups of anal carcinomas with clinical implications.
Br J Cancer 2008 Apr;98(7):1264-73. Epub 2008 mar 18
PMID: 18349847
Chronic cancer-related fatigue in long-term survivors of testicular cancer.
J Psychosom Res 2008 Apr;64(4):363-71.
PMID: 18374735
Global gene expression analyses reveal changes in biological processes after hyperthermia in a rat glioma model.
Int J Hyperthermia 2008 Aug;24(5):425-41.
PMID: 18608572
Dynamic contrast enhanced magnetic resonance imaging of bladder cancer and implications for biological image-adapted radiotherapy.
Acta Oncol 2008;47(7):1257-64.
PMID: 18618299
2008 ESHO-BSD Award Winner--Gerard C. van Rhoon.
Int J Hyperthermia 2008 Aug;24(5):444-5.
PMID: 18716944
Predicted cardiovascular mortality and reported cardiovascular morbidity in testicular cancer survivors.
J Cancer Surviv 2008 Sep;2(3):128-37. Epub 2008 mai 29
PMID: 18792787
Components of the metabolic syndrome in long-term survivors of testicular cancer.
Ann Oncol 2007 Feb;18(2):241-8. Epub 2006 okt 23
PMID: 17060482
Transient neurological adverse effects following low dose radiation therapy for early stage testicular seminoma.
Radiother Oncol 2007 Feb;82(2):137-44. Epub 2006 des 26
PMID: 17189656
Gonadal dysfunction and fertility problems in cancer survivors.
Acta Oncol 2007;46(4):480-9.
PMID: 17497315
Is the sexual function compromised in long-term testicular cancer survivors?
Eur Urol 2007 Nov;52(5):1438-47. Epub 2007 mar 1
PMID: 17350159
Quantification of S100A12 (EN-RAGE) in blood varies with sampling method, calcium and heparin.
Scand J Immunol 2007 Feb;65(2):192-201.
PMID: 17257225
Time patterns of changes in biomarkers, symptoms and histopathology during pelvic radiotherapy.
Acta Oncol 2007;46(5):639-50.
PMID: 17562440
Clinical characteristics and outcomes in patients with advanced rectal cancer: a national prospective cohort study.
Dis Colon Rectum 2007 Mar;50(3):285-91.
PMID: 17235720
Secondary treatment and predictive factors for second-line chemotherapy after first-line oxaliplatin-based therapy in metastatic colorectal cancer.
Acta Oncol 2007;46(7):982-8.
PMID: 17917829
[Radiotherapy of rectal cancer.]
Tidsskr Nor Laegeforen 2007 Nov;127(23):3090-3.
PMID: 18049501
[Adjuvant chemotherapy for colon cancer]
Tidsskr Nor Laegeforen 2007 Nov;127(23):3094-6.
PMID: 18049502
Nationwide quality assurance of rectal cancer treatment.
Colorectal Dis 2006 Mar;8(3):224-9.
PMID: 16466564
Radiation dose escalation combined with hormone therapy improves outcome in localised prostate cancer.
Acta Oncol 2006;45(4):454-62.
PMID: 16760182
A concomitant tumour boost in bladder irradiation: patient suitability and the potential of intensity-modulated radiotherapy.
Radiother Oncol 2006 Jul;80(1):98-105. Epub 2006 jul 28
PMID: 16876274
Side effects and cancer-related stress determine quality of life in long-term survivors of testicular cancer.
J Clin Oncol 2005 May;23(13):3061-8.
PMID: 15860864
First results of triple-modality treatment combining radiotherapy, chemotherapy, and hyperthermia for the treatment of patients with stage IIB, III, and IVA cervical carcinoma.
Cancer 2005 Aug;104(4):763-70.
PMID: 15968685
Paternity following treatment for testicular cancer.
J Natl Cancer Inst 2005 Nov;97(21):1580-8.
PMID: 16264178
Adjuvant chemotherapy in colorectal cancer: a joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group.
Acta Oncol 2005;44(8):904-12.
PMID: 16332600
Chemoradiotherapy of anal carcinoma: Survival and recurrence in an unselected national cohort.
Int J Rad Oncol Biol Phys In Press 2011
Phase III trial of cetuximab with continuous or intermeittent fluorouracil, leucovorin and oxaliplatin (Nordic FLOX) versus FLOX
J Clin Oncol In Press 2011
Faglige anbefalinger for behandling av analcancer.
Strålevernsrapport 2011:5, Statens Strålevern, Oslo, 1-34.
Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer.
Manuscript Innsendt
Expression of DSG1 and DSC1 are prognostic markers in anal carcinoma patients.
Brit J Cancer InPress 2011
Fibroblast growth factor 2- A predictor of outcome for patients irradiated for stage II-III non-small cell lung cancer.
Int J Radiat Oncol Biol Phys 82:442-7, 2012.
The prognostic impact of tumor cell expression of estrogen receptor-a, progesterone receptor, and androgen receptor in patients
Cancer 118:157-63, 2012.
T2 Kreftsykdommer.
Norsk legemiddelhåndbok for helsepersonell 2010. A. Vilberg (Ed). Foreningen for utgivelse av Legemiddelhåndboken, Oslo, 103-125, 2010.
266. L 2. Legemidler i behandlingen av kreftsykdommer.
Norsk legemiddelhåndbok for helsepersonell 2010. A. Vilberg (Ed). Foreningen for utgivelse av Legemiddelhåndboken, Oslo, 775-820, 2010
Medikamentell kreftbehandling. Cytostaticaboken 7. edition.
Bok. Farmakologisk Inst, Univ. i Oslo, Oslo 2009, pp 1-495
Kreftceller og kjemoterapi.
Medikamentell kreftbehandling. Cytostaticaboken. Farmakol. Inst, UiO, pp 12-37.
Medikamentell kreftbehandling.
Medikamentell kreftbehandling. Cytostaticaboken. Farmakol. Inst, UiO, pp 38-45.
Bivirkninger
Medikamentell kreftbehandling. Cytostaticaboken. Farmakol. Inst, UiO, pp 56-74.
Gastrointestinal kreft.
Medikamentell kreftbehandling. Cytostaticaboken. Farmakol. Inst, UiO, pp 363-375.
Kreft i nyre, ureter, urinblære og prostata.
Medikamentell kreftbehandling. Cytostaticaboken. Farmakol. Inst, UiO, pp 396-403.
Cancer testis.
Medikamentell kreftbehandling. Cytostaticaboken. Farmakol. Inst, UiO, pp 404-411.
Current status of vascualr targeting drugs and hyperthermia
int J Hyperthermia In Press
Gene expression reveals two distinct groups of anal carcinomas with clinical implications
Br J Cancer Cond. accepted
Gene expression analyses reveal biological processes associated with hyperthermia in a rat glioma model
Int J Hyperthermia Cond. accepted
The effects of cancer and cancer treatments on male reproductive function.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16763643&query_hl=12&itool=pubmed_docsum
Short-time infusion of oxaliplatin in combination with capecitabine (XELOX30) as second-line therapy in patients with advanced c
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16291583&query_hl=15&itool=pubmed_docsum
Gene expression in poorly differentiated papillary thyroid carcinomas.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16676402&query_hl=16&itool=pubmed_docsum
PhD
- Disputert:
- desember 2012
- Hovedveileder:
- Olav Dahl
Long-term effects in survivors of testicular cancer with emphasis on fertility and neurological side effects.
- Disputert:
- november 2010
- Hovedveileder:
- Olav Dahl
Radiation therapy combined with hormone treatment for primary prostate cancer. Effects of radiation dose escalations and assessm
- Disputert:
- mai 2009
- Hovedveileder:
- Olav Dahl
Molecular and biological alterations in tumors after hyperthermia- Hyperthermia in addition to metronomic chemotherapy in rats a
- Disputert:
- desember 2009
- Hovedveileder:
- Øystein Fluge
Inflammatory biomarkers with focus on Calprotectin and S100A12
- Disputert:
- februar 2007
- Hovedveileder:
- Olav Dahl
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest