Exploration and Validation of Angiogenesis Markers in Human Cancers
- Prosjektnummer
- 911403
- Ansvarlig person
- Lars A. Akslen
- Institusjon
- Universitetet i Bergen
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Cancer
- Forskningsaktivitet
- 4. Detection and Diagnosis
Efficient in vivo vascularization of tissue-engineering scaffolds.
J Tissue Eng Regen Med 2011 Apr;5(4):e52-62. Epub 2010 sep 23
PMID: 20865694
Gene expression patterns related to vascular invasion and aggressive features in endometrial cancer.
Am J Pathol 2011 Feb;178(2):861-71.
PMID: 21281818
Reprogramming of cell junction modules during stepwise epithelial to mesenchymal transition and accumulation of malignant features in vitro in a prostate cell model.
Exp Cell Res 2011 Jan;317(2):234-47. Epub 2010 okt 20
PMID: 20969863
Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer.
Clin Cancer Res 2011 May;17(10):3368-77. Epub 2011 jan 17
PMID: 21242118
High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer.
Br J Cancer 2011 Mar;104(6):921-6. Epub 2011 feb 22
PMID: 21343929
Receptor for activated protein C kinase 1 (RACK1) is overexpressed in papillary thyroid carcinoma.
Thyroid 2011 Nov;21(11):1217-25. Epub 2011 okt 18
PMID: 22007921
Genome-wide association study identifies three new melanoma susceptibility loci.
Nat Genet 2011 Nov;43(11):1108-13. Epub 2011 okt 9
PMID: 21983787
Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer.
Br J Cancer 2011 Jun;105(1):9-12. Epub 2011 jun 14
PMID: 21673677
Evolution in endometrial cancer: evidence from an immunohistochemical study.
Int J Gynecol Cancer 2011 Feb;21(2):316-22.
PMID: 21734474
Vascular proliferation is increased in basal-like breast cancer.
Breast Cancer Res Treat 2011 Dec;130(3):1063-71. Epub 2011 aug 28
PMID: 21874512
Vascular proliferation is a prognostic factor in breast cancer.
Breast Cancer Res Treat 2012 Jun;133(2):501-10. Epub 2011 sep 27
PMID: 21947750
In vivo MRI and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts.
J Magn Reson Imaging 2012 May;35(5):1098-107. Epub 2011 des 14
PMID: 22170753
Expression of aldehyde dehydrogenase 1 (ALDH1) is associated with basal-like markers and features of aggressive tumours in African breast cancer.
Br J Cancer 2010 Jan;102(2):369-75. Epub 2009 des 15
PMID: 20010944
Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
Proc Natl Acad Sci U S A 2010 Jan;107(3):1124-9. Epub 2009 des 28
PMID: 20080645
Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma.
BMC Cancer 2010;10():140. Epub 2010 apr 14
PMID: 20398247
Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies.
PLoS Med 2010;7(5):e1000279. Epub 2010 mai 25
PMID: 20520800
Stathmin is superior to AKT and phospho-AKT staining for the detection of phosphoinositide 3-kinase activation and aggressive endometrial cancer.
Histopathology 2010 Oct;57(4):641-6.
PMID: 20955391
Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer.
J Clin Pathol 2009 Feb;62(2):139-46. Epub 2008 aug 4
PMID: 18682421
Importance of tumour cell invasion in blood and lymphatic vasculature among patients with endometrial carcinoma.
Histopathology 2009 Jan;54(2):174-83.
PMID: 19207942
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas.
Clin Cancer Res 2009 Feb;15(4):1417-27. Epub 2009 feb 3
PMID: 19193619
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation.
Proc Natl Acad Sci U S A 2009 Mar;106(12):4834-9. Epub 2009 mar 4
PMID: 19261849
Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis.
PLoS One 2009;4(3):e4687. Epub 2009 mar 5
PMID: 19262738
Identification of a CDK4 R24H mutation-positive melanoma family by analysis of early-onset melanoma patients in Latvia.
Melanoma Res 2009 Apr;19(2):119-22.
PMID: 19238106
Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes.
Clin Cancer Res 2009 Apr;15(7):2302-10. Epub 2009 mar 24
PMID: 19318481
Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance.
Clin Cancer Res 2009 May;15(10):3484-94. Epub 2009 mai 15
PMID: 19447865
Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer.
Cancer Res 2009 Jun;69(11):4708-15.
PMID: 19487287
Plasma calprotectin concentrations in women with endometrial carcinoma.
Gynecol Oncol 2009 Sep;114(3):491-5. Epub 2009 jul 3
PMID: 19577278
Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1.
Proc Natl Acad Sci U S A 2009 Jul;106(29):12115-20. Epub 2009 jul 6
PMID: 19581582
Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model.
PLoS One 2009;4(7):e6381. Epub 2009 jul 28
PMID: 19636430
TMPRSS2:ERG fusion transcripts in urine from prostate cancer patients correlate with a less favorable prognosis.
APMIS 2009 Aug;117(8):575-82.
PMID: 19664128
Estrogen receptor beta--an independent prognostic marker in estrogen receptor alpha and progesterone receptor-positive breast cancer?
APMIS 2009 Sep;117(9):644-50.
PMID: 19703124
Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis.
Br J Cancer 2009 Oct;101(8):1282-9. Epub 2009 sep 22
PMID: 19773751
Biologic markers in endometrial cancer treatment.
APMIS 2009 Oct;117(10):693-707.
PMID: 19775337
Secondary breast cancer: a 5-year population-based study with review of the literature.
APMIS 2009 Oct;117(10):762-7.
PMID: 19775345
Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting.
Am J Obstet Gynecol 2009 Dec;201(6):603.e1-7. Epub 2009 okt 3
PMID: 19800606
Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas.
BMC Cancer 2009;9():425. Epub 2009 des 8
PMID: 19968886
Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas.
Genes Chromosomes Cancer 2008 Feb;47(2):175-84.
PMID: 18023021
HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas.
Int J Oncol 2008 Feb;32(2):307-16.
PMID: 18202752
Mutation analysis of the EGFR-NRAS-BRAF pathway in melanomas from black Africans and other subgroups of cutaneous melanoma.
Melanoma Res 2008 Feb;18(1):29-35.
PMID: 18227705
Loss of BMI-1 expression is associated with clinical progress of malignant melanoma.
Mod Pathol 2008 May;21(5):583-90. Epub 2008 feb 8
PMID: 18246051
Independent prognostic value of the basal-like phenotype of breast cancer and associations with EGFR and candidate stem cell marker BMI-1.
Histopathology 2008 Feb;52(3):370-80.
PMID: 18269588
Hyperthermia improves the antitumour effect of metronomic cyclophosphamide in a rat transplantable brain tumour.
Radiother Oncol 2008 Mar;86(3):435-42. Epub 2008 mar 4
PMID: 18313158
WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence.
Clin Cancer Res 2008 Mar;14(5):1397-406.
PMID: 18316561
Dr. Folkman's legacy-a life of angiogenesis research.
APMIS 2008 Feb;116(2):89-92.
PMID: 18321358
Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma.
Br J Cancer 2008 May;98(10):1662-9. Epub 2008 mai 13
PMID: 18475299
Drug-sensitive FGFR2 mutations in endometrial carcinoma.
Proc Natl Acad Sci U S A 2008 Jun;105(25):8713-7. Epub 2008 jun 13
PMID: 18552176
GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival.
Am J Obstet Gynecol 2008 Nov;199(5):543.e1-7. Epub 2008 jul 3
PMID: 18599012
Expression of EGFR and c-kit is associated with the basal-like phenotype in breast carcinomas of African women.
APMIS 2008 Jun;116(6):515-25.
PMID: 18754326
Tumor dormancy--from basic mechanisms to clinical practice.
APMIS 2008 Jul-Aug;116(7-8):545-7.
PMID: 18834400
Tumor-vascular interactions and tumor dormancy.
APMIS 2008 Jul-Aug;116(7-8):569-85.
PMID: 18834403
Epithelial to mesenchymal transition of a primary prostate cell line with switches of cell adhesion modules but without malignant transformation.
PLoS One 2008;3(10):e3368. Epub 2008 okt 13
PMID: 18852876
Tumor necrosis is associated with increased alphav beta3 integrin expression and poor prognosis in nodular cutaneous melanomas.
BMC Cancer 2008 Dec;8(1):362. Epub 2008 des 5
PMID: 19061491
Tumor Dormancy (Special Issue).
APMIS 2008; 116 (7-8):541-770.
Gene signatures and prognostic factors in endometrial cancer. A study with special focus on vascular invasion
- Disputert:
- april 2011
- Hovedveileder:
- LARS A AKSLEN
Angiogenesis and Epithelial-Mesenchymal Transition in Prostate Cancer
- Disputert:
- september 2011
- Hovedveileder:
- LARS A AKSLEN
ERG and SIM2 transcription factors in prostate cancer – their role in carcinogenesis and potential clinical utility
- Disputert:
- januar 2011
- Hovedveileder:
- KARL H KALLAND
Molecular markers in breast carcinoma. A study with focus on molecular phenotypes, angiogenesis and stem cells in an African pop
- Disputert:
- september 2010
- Hovedveileder:
- Lars A. Akslen
Biological and prognostic markers of breast carcinoma
- Disputert:
- februar 2010
- Hovedveileder:
- Lars A. Akslen
Biologic and prognostic markers in endometrial carcinoma. A study with special focus on tumor markers in curettage specimens.
- Disputert:
- juni 2008
- Hovedveileder:
- Helga B. Salvesen
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest