Skjoldbruskkjertelkreft
- Prosjektnummer
- 911563
- Ansvarlig person
- Thomas Arnesen
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Cancer, Metabolic and Endocrine
- Forskningsaktivitet
- 4. Detection and Diagnosis, 5. Treatment Developement
F18-FDG-PET for recurrent differentiated thyroid cancer: a systematic meta-analysis.
Acta Radiol 2015 Jul 9. Epub 2015 jul 9
PMID: 26163534
Novel inflammatory biomarkers in primary hyperparathyroidism.
Eur J Endocrinol 2015 Jul;173(1):9-17. Epub 2015 apr 7
PMID: 25850829
Post-PET ultrasound improves specificity of 18F-FDG-PET for recurrent differentiated thyroid cancer while maintaining sensitivity.
Acta Radiol 2015 Nov;56(11):1350-60. Epub 2015 mar 13
PMID: 25770086
Effects of parathyroidectomy versus observation on the development of vertebral fractures in mild primary hyperparathyroidism.
J Clin Endocrinol Metab 2015 Apr;100(4):1359-67. Epub 2015 jan 30
PMID: 25636048
Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials.
Lancet 2015 Oct 3;386(10001):1341-52. Epub 2015 jul 23
PMID: 26211827
Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials.
Lancet 2015 Oct 3;386(10001):1353-61. Epub 2015 jul 23
PMID: 26211824
The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4.
PLoS One 2011;6(9):e24713. Epub 2011 sep 15
PMID: 21935442
NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation.
PLoS Genet 2011 Jul;7(7):e1002169. Epub 2011 jul 7
PMID: 21750686
Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase.
Mol Cell Proteomics 2011 May;10(5):M110.004580. Epub 2011 mar 7
PMID: 21383206
Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency.
Am J Hum Genet 2011 Jul;89(1):28-43. Epub 2011 jun 23
PMID: 21700266
Depletion of the human N(alpha)-terminal acetyltransferase A (hNatA) induces p53-dependent apoptosis and p53-independent growth inhibition.
Int J Cancer 2010 Feb. Epub 2010 feb 22
PMID: 20178098
The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation.
Mol Cell Biol 2010 Apr;30(8):1898-909. Epub 2010 feb 12
PMID: 20154145
Development of NAT inhibitors for the potential use in thyroid cancer chemotherapy
Abstract 554, Am Thyr Assoc , www.thyroid.org, Oct 2012
Depletion of human N-terminal acetyltransferase hNaa30 leads to Golgi scattering and re-localization of the Golgi-associated GTP
Submitted,,under reviosn
The protein N-terminal acetyltransferase NatA: A novel target for thyroid cancer chemotherapy?
Poster 0196, 14th Int Thyroid Congress. www.itc2010.com
A Norwegian-US initiative: NatA inhibitor development
Poster Transatlantic Science Week, Washington DC, www.norway.org/scienceweek
The human protein Na-terminal acetyltransferases NatA and NatC : cellular functions and molecular basis for use in chemotherapy
- Disputert:
- januar 2010
- Hovedveileder:
- Jan Erik Varhaug
The human protein N-a-acetyltransferase complexes hNatA,hNatB, and hNatC : identification and functional characterization
- Disputert:
- juni 2010
- Hovedveileder:
- Jan Erik VArhaug
- Jan Erik Varhaug Prosjektleder
- Michael Brauckhoff Prosjektleder
- Nina Glomnes Prosjektdeltaker
- Thomas Arnesen Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest