Aging - cognition, imaging and genetics
- Prosjektnummer
- 911687
- Ansvarlig person
- Astri Johansen Lundervold
- Institusjon
- Haraldsplass Diakonale Sykehus
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Neurological
- Forskningsaktivitet
- 4. Detection and Diagnosis
Longitudinal Changes in Familiarity, Free and Cued Odor Identification, and Edibility Judgments for Odors in Aging Individuals.
Chem Senses 2015 Nov 6. Epub 2015 nov 6
PMID: 26547014
Common variants in the ARC gene are not associated with cognitive abilities.
Brain Behav 2015 Oct;5(10):e00376. Epub 2015 sep 3
PMID: 26516611
Genome-wide autozygosity is associated with lower general cognitive ability.
Mol Psychiatry 2015 Sep 22. Epub 2015 sep 22
PMID: 26390830
Longitudinal Changes in Odor Identification Performance and Neuropsychological Measures in Aging Individuals.
Neuropsychology 2015 Jun 15. Epub 2015 jun 15
PMID: 26076320
Fractional anisotropy shows differential reduction in frontal-subcortical fiber bundles-A longitudinal MRI study of 76 middle-aged and older adults.
Front Aging Neurosci 2015;7():81. Epub 2015 mai 15
PMID: 26029102
Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment.
Am J Med Genet B Neuropsychiatr Genet 2015 Jul;168B(5):363-73. Epub 2015 mai 7
PMID: 25951819
Genetic basis of a cognitive complexity metric.
PLoS One 2015;10(4):e0123886. Epub 2015 apr 10
PMID: 25860228
Even cognitively well-functioning adults are unaware of their olfactory dysfunction: Implications for ENT clinicians and researchers.
Rhinology 2015 Mar;53(1):89-94.
PMID: 25756084
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).
Mol Psychiatry 2015 Feb;20(2):183-92. Epub 2015 feb 3
PMID: 25644384
High-expanding cortical regions in human development and evolution are related to higher intellectual abilities.
Cereb Cortex 2015 Jan;25(1):26-34. Epub 2013 aug 19
PMID: 23960203
Does it Matter How We Pose the Question "How is Your Sense of Smell?"
Chemosens Percept 2014;7(3-4):103-107. Epub 2014 jul 29
PMID: 25485033
Salient measures of inhibition and switching are associated with frontal lobe gray matter volume in healthy middle-aged and older adults.
Neuropsychology 2014 Nov;28(6):859-69. Epub 2014 mai 12
PMID: 24819063
Interactive visual analysis of heterogeneous cohort-study data.
IEEE Comput Graph Appl 2014 Sep-Oct;34(5):70-82.
PMID: 25248201
GWAS-based pathway analysis differentiates between fluid and crystallized intelligence.
Genes Brain Behav 2014 Sep;13(7):663-74. Epub 2014 aug 8
PMID: 24975275
Age and sex related changes in episodic memory function in middle aged and older adults.
Scand J Psychol 2014 Jun;55(3):225-32. Epub 2014 mar 6
PMID: 24601911
Lack of association of the rs1344706 ZNF804A variant with cognitive functions and DTI indices of white matter microstructure in two independent healthy populations.
Psychiatry Res 2014 Apr 30;222(1-2):60-6. Epub 2014 feb 22
PMID: 24636489
Using ancestry-informative markers to identify fine structure across 15 populations of European origin.
Eur J Hum Genet 2014 Oct;22(10):1190-200. Epub 2014 feb 19
PMID: 24549058
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).
Mol Psychiatry 2014 Feb;19(2):168-74. Epub 2013 des 17
PMID: 24342994
Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins.
Transl Psychiatry 2014;4():e341. Epub 2014 jan 7
PMID: 24399044
A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder.
PLoS One 2013;8(12):e81052. Epub 2013 des 12
PMID: 24349030
General fluid-type intelligence is related to indices of white matter structure in middle-aged and old adults.
Neuroimage 2013 Dec;83():372-83. Epub 2013 jun 19
PMID: 23791837
Local/non-local regularized image segmentation using graph-cuts: application to dynamic and multispectral MRI.
Int J Comput Assist Radiol Surg 2013 Nov;8(6):1073-84. Epub 2013 jun 14
PMID: 23765212
Subthreshold Depressive Symptoms have a Negative Impact on Cognitive Functioning in Middle-Aged and Older Males.
Front Psychol 2013;4():309. Epub 2013 mai 31
PMID: 23755036
Registration of FA and T1-weighted MRI data of healthy human brain based on template matching and normalized cross-correlation.
J Digit Imaging 2013 Aug;26(4):774-85.
PMID: 23288436
White matter fiber tracking directed by interpolating splines and a methodological framework for evaluation.
Front Neuroinform 2013;7():13. Epub 2013 jul 26
PMID: 23898264
Neuropsychological performance in older insomniacs.
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 2013;20(1):34-48. Epub 2012 apr 10
PMID: 22490041
A vascular approach to mild amnestic cognitive impairment: a pilot study.
Acta Neurol Scand Suppl 2013.
PMID: 23190296
Imaging and cognitive genetics: the Norwegian Cognitive NeuroGenetics sample.
Twin Res Hum Genet 2012 Jun;15(3):442-52.
PMID: 22856377
Episodic memory of APOE e4 carriers is correlated with fractional anisotropy, but not cortical thickness, in the medial temporal lobe.
Neuroimage 2012 Oct;63(1):507-16. Epub 2012 jul 10
PMID: 22796460
Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders.
PLoS One 2012;7(2):e31687. Epub 2012 feb 22
PMID: 22384057
DNA base excision repair gene polymorphisms modulate human cognitive performance and decline during normal life span.
Mech Ageing Dev 2011 Aug;132(8-9):449-58. Epub 2011 aug 22
PMID: 21884718
Genome-wide association studies establish that human intelligence is highly heritable and polygenic.
Mol Psychiatry 2011 Oct;16(10):996-1005. Epub 2011 aug 9
PMID: 21826061
Automated approaches for analysis of multimodal MRI acquisitions in a study of cognitive aging.
Comput Methods Programs Biomed 2012 Jun;106(3):328-41. Epub 2011 jun 12
PMID: 21663993
Increased hippocampal default mode synchronization during rest in middle-aged and elderly APOE e4 carriers: relationships with memory performance.
J Neurosci 2011 May;31(21):7775-83.
PMID: 21613490
Unawareness of olfactory dysfunction and its association with cognitive functioning in middle aged and old adults.
Arch Clin Neuropsychol 2011 Apr;26(3):260-9. Epub 2011 apr 6
PMID: 21474482
Cortico-striatal connectivity and cognition in normal aging: a combined DTI and resting state fMRI study.
Neuroimage 2011 Mar;55(1):24-31. Epub 2010 nov 10
PMID: 21073962
Hypothesis Generation by Interactive Visual Exploration of Heterogeneous Medical Data.
In Holzinger A, Pasi G (eds.) Human-Computer Interaction and Knowledge Discovery in Complex, Unstructured, Big Data. Springer LNCS 7947, pp. 1-12, 2013.
Representative Factor Generation for the Interactive Visual Analysis of High-Dimensional Data.
IEEE Transactions on visualization and computer graphics, 2012, vol. 18, no. 12, p. 2621-2630.
Structural brain network of general fluid type intelligence in 101 healthy elderly subjects
Human Brain Mapping, Beijing,June, 2012
Assessing functional brain connectivity changes in healthy aging using R-fMRI and the MIC similarity
Human Brain Mapping, Beijing, June 2012
fluid intelligence and information processing speed are related to white matter microstructure in major anatomical pathways at 4
Trondheim, 28.11.2012
Assessing functional brain connectivity changes in healthy elderly using resting-state fMRI and graph theory.
Bergen, januar 2012
Identification of Cortical Thickness and Area Patterns Associated With Cognitive Processes.
Poster, ICQG, Edinburgh, June 2012.
Identification of Cortical Thickness and Area Patterns Associated With Cognitive Processes.
HBM, Beijing, June 2012.
Reduced-Rank Regression as a Multivariate Technique for GWAS: Application to Healthy Norwegian Individuals Data.
Oral pres. WCPG, Hamburgh, Oct. 2012
Fast marching tractography from multiple diffusion sensitizing directions in MR-DTI from the brain.
Proceedings of the 7th International Symposium on Image and Signal Processing and Analysis (ISPA 2011), September 4-6, 2011, Dubrovnik, Croatia
White matter (wm) fiber integrity in cognitive ageing: a combined MR image segmentation and tractography approach
Medviz, Bergen, 2011
Correlating cortical thickness and white matter integrity in normal aging: A combined segmentation and tractography approach usi
Human Brain Mapping Conference, Quebeck, 26-30 June, 2011
White matter integrity changes in frontally projecting fibers – a MRI study of healthy aging.
International Conference on Cognitive Neuroscience, Mallorca, 22. - 29. Sept. 2011
Genom-wide association analysis of cognitive abilities in a healthy Norwegian sample with replication in a large UK-based sample
2011
Assessing Differences in Resting State Functional Brain Connectivity with Complex Network Analysis
MedViz Report nr. 9 2011- ISSN 1891-1799,
Analyse de le connectivité fonctionnelle du cerveau par la théorie des graphes
Medviz report nr. 10 2011, ISSN 1891-179X
”White matter integrity changes in frontally projecting fibers –A MRI study of healthy aging”
- Healthy brain i Oslo (06.06.11-07.06.11)
”White matter integrity changes in frontally projecting fibers –A MRI study of healthy aging”
- ICG på solstrand (16.06.11-18.06.11)
”Frontally projecting fibers in healthy aging, A three wave longitudinal study”
- MedIm (21.11.11 – 22.11.11)
White matter integrity change in healthy aging: A combined region- and tract-based MRI study.
2nd National PhD conference in Medical Imaging, Bergen, NO
Longitudinal structural changes in the aging brain - in context of parieto-frontal integration theory of intelligence
3nd National PhD conference in Medical Imaging, Oslo, NO
"Resting state FMRI in healthy APOE carriers: increased synchronization in the default mode network correlates negatively with m
2nd National PhD conference in Meidical Imaging, Bergen
Structural and functional brain imaging and cognition in aging and stroke
- Disputert:
- juni 2015
- Hovedveileder:
- Lars Thomassen
A genetic study of schizophrenia and bipolar disorder
- Disputert:
- januar 2015
- Hovedveileder:
- Professor Stéphanie Le Hellard
- Astri Johansen Lundervold Prosjektleder
- Judit Haász Prosjektdeltaker
- Erlend Hodneland Prosjektdeltaker
- Alexandra Vik Ph.d.-kandidat
- Steinunn Adolfsdottir Ph.d.-kandidat
- Eike Wehling Prosjektdeltaker
- Arvid Lundervold Prosjektdeltaker
- Rune Eikeland Ph.d.-kandidat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest