The SCHAD enzyme – A novel regulator of insulin secretion
- Prosjektnummer
- 911787
- Ansvarlig person
- Anders Molven
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Metabolic and Endocrine
- Forskningsaktivitet
- 1. Underpinning
Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry.
Diabetologia 2017 Apr;60(4):625-635. Epub 2016 des 2
PMID: 27913849
Functional Investigations of HNF1A Identify Rare Variants as Risk Factors for Type 2 Diabetes in the General Population.
Diabetes 2017 02;66(2):335-346. Epub 2016 nov 29
PMID: 27899486
PI3-kinase mutation linked to insulin and growth factor resistance in vivo.
J Clin Invest 2016 Apr 01;126(4):1401-12. Epub 2016 mar 14
PMID: 26974159
The Hypoglycemic Phenotype Is Islet Cell-Autonomous in Short-Chain Hydroxyacyl-CoA Dehydrogenase-Deficient Mice.
Diabetes 2016 Jun;65(6):1672-8. Epub 2016 mar 7
PMID: 26953163
The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey).
Int J Endocrinol 2015;2015():164652. Epub 2015 mai 18
PMID: 26089876
A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis.
Nat Genet 2015 May;47(5):518-22. Epub 2015 mar 16
PMID: 25774637
Glycogenin-2 is dispensable for liver glycogen synthesis and glucagon-stimulated glucose release.
J Clin Endocrinol Metab 2015 May;100(5):E767-75. Epub 2015 mar 9
PMID: 25751106
Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction.
J Biol Chem 2014 Oct 17;289(42):29097-111. Epub 2014 aug 25
PMID: 25160620
Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid.
Diabetes 2014 Jan;63(1):259-69. Epub 2013 sep 23
PMID: 24062244
Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.
Nat Genet 2013 Nov;45(11):1380-5. Epub 2013 okt 6
PMID: 24097065
Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young).
PLoS One 2013;8(4):e60229. Epub 2013 apr 2
PMID: 23565203
SHORT syndrome with partial lipodystrophy due to impaired phosphatidylinositol 3 kinase signaling.
Am J Hum Genet 2013 Jul 11;93(1):150-7. Epub 2013 jun 27
PMID: 23810379
Prevalence of monogenic diabetes in the population-based Norwegian Childhood Diabetes Registry.
Diabetologia 2013 Jul;56(7):1512-9. Epub 2013 apr 27
PMID: 23624530
Type 2 diabetes genes – Present status and data from Norwegian studies.
Norsk Epidemiologi (2013); 23:9-22
Monogenic diabetes mellitus in Norway.
Norsk Epidemiologi (2013); 23:55-60
- Pål Rasmus Njølstad Prosjektdeltaker
- Man Hung Choi Prosjektdeltaker
- Johanna Lüdeke Ph.d.-kandidat
- Kelly Velasco Pinto Postdoktor
- Anders Molven Prosjektleder
- Solrun Steine Prosjektdeltaker
- Rohit N Kulkarni Prosjektdeltaker
- Line Pedersen Prosjektdeltaker
- Kelly Velasco Prosjektdeltaker
- Rohit Rajesh Kulkarni Prosjektdeltaker
- Jennifer Hollister-Lock Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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