Molecular determinants of response to endocrine therapy in breast cancer
- Prosjektnummer
- 911791
- Ansvarlig person
- Gunnar Mellgren
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Metabolic and Endocrine
- Forskningsaktivitet
- 2. Aetiology, 4. Detection and Diagnosis
Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer.
PLoS One 2015;10(8):e0134351. Epub 2015 aug 6
PMID: 26247365
Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells.
Biochim Biophys Acta 2015 Oct;1853(10 Pt A):2383-91. Epub 2015 mai 16
PMID: 25986860
The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells.
PLoS One 2015;10(4):e0122339. Epub 2015 apr 13
PMID: 25867603
cAMP response element-binding protein interacts with and stimulates the proteasomal degradation of the nuclear receptor coactivator GRIP1.
Endocrinology 2013 Apr;154(4):1513-27. Epub 2013 mar 5
PMID: 23462962
Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of mcf-7 breast cancer cells.
PLoS One 2013;8(7):e70096. Epub 2013 jul 30
PMID: 23936147
Inverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue.
PLoS One 2013;8(8):e74618. Epub 2013 aug 22
PMID: 23991224
Steroid receptor coactivators during short-term estrogen deprivation
Cold Spring Laboratory Meeting 28.10.2014-01.11.2014:Nuclear Receptors and Disease
Role of Steroid Receptor Co-Activator SRC-2 in the Hepatocellular Response to Metformin
Cold Spring Laboratory Meeting 28.10.2014-01.11.2014:Nuclear Receptors and Disease
SHARED AND DISTINCT FUNCTIONS OF SRC-2 AND SRC-3.
Cold Spring Laboratory Meeting 28.10.2014-01.11.2014:Nuclear Receptors and Disease
Regulation and function of steroid receptor coactivator 2 in hepatoma and breast cancer cells
- Disputert:
- desember 2015
- Hovedveileder:
- Gunnar Mellgren
- Jørn V. Sagen Prosjektdeltaker
- Vidar Martin Steen Prosjektdeltaker
- Ernst Asbjørn Lien Prosjektdeltaker
- Olivera Bozickovic Ph.d.-kandidat
- Bernardo Bonanni Prosjektdeltaker
- Marianne Flågeng Postdoktor
- Per Eystein Lønning Prosjektdeltaker
- Gunnar Mellgren Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest