Redefinering av autoimmunt polyendokrint syndrom type 1 - ny ikke-klassisk form kamulert som vanlig autoimmunitet
- Prosjektnummer
- 911878
- Ansvarlig person
- Eystein Husebye
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Inflammatory and Immune System, Metabolic and Endocrine
- Forskningsaktivitet
- 2. Aetiology, 4. Detection and Diagnosis
A Variant in the BACH2 Gene Is Associated With Susceptibility to Autoimmune Addison's Disease in Humans.
J Clin Endocrinol Metab 2016 Nov;101(11):3865-3869. Epub 2016 sep 28
PMID: 27680876
AIRE-mutations and autoimmune disease.
Curr Opin Immunol 2016 Dec;43():8-15. Epub 2016 aug 6
PMID: 27504588
AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies.
Cell 2016 Jul 28;166(3):582-95. Epub 2016 jul 14
PMID: 27426947
Adrenal Insufficiency Therapy: How to Keep the Balance between Good Quality of Life and Low Risk for Long-Term Side Effects?
Front Horm Res 2016;46():196-210. Epub 2016 mai 23
PMID: 27212041
Epidemiology and Health-Related Quality of Life in Hypoparathyroidism in Norway.
J Clin Endocrinol Metab 2016 Aug;101(8):3045-53. Epub 2016 mai 17
PMID: 27186861
Autoimmune regulator and self-tolerance - molecular and clinical aspects.
Immunol Rev 2016 May;271(1):127-40.
PMID: 27088911
MANAGEMENT OF ENDOCRINE DISEASE: Epidemiology, quality of life and complications of primary adrenal insufficiency: a review.
Eur J Endocrinol 2016 Sep;175(3):R107-16. Epub 2016 apr 11
PMID: 27068688
Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.
J Am Soc Nephrol 2016 Oct;27(10):3220-3228. Epub 2016 mar 16
PMID: 26984885
Anticommensal Responses Are Associated with Regulatory T Cell Defect in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients.
J Immunol 2016 Apr 01;196(7):2955-64. Epub 2016 feb 22
PMID: 26903483
Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1.
Sci Rep 2016 Feb 01;6():20104. Epub 2016 feb 1
PMID: 26830021
Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline.
J Clin Endocrinol Metab 2016 Feb;101(2):364-89. Epub 2016 jan 13
PMID: 26760044
Effect of a pre-exercise hydrocortisone dose on short-term physical performance in female patients with primary adrenal failure.
Eur J Endocrinol 2016 Jan;174(1):97-105. Epub 2015 okt 22
PMID: 26494876
Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6.
Endocr Connect 2015 Dec;4(4):215-22. Epub 2015 aug 13
PMID: 26273099
CTLA-4 as a genetic determinant in autoimmune Addison's disease.
Genes Immun 2015 Sep;16(6):430-6. Epub 2015 jul 23
PMID: 26204230
Transglutaminase 4 as a prostate autoantigen in male subfertility.
Sci Transl Med 2015 Jun 17;7(292):292ra101.
PMID: 26084804
Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases.
Immunity 2015 Jun 16;42(6):1185-96.
PMID: 26084028
Linkage Analysis in Autoimmune Addison's Disease: NFATC1 as a Potential Novel Susceptibility Locus.
PLoS One 2015;10(6):e0123550. Epub 2015 jun 4
PMID: 26042420
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.
Nat Immunol 2015 Jul;16(7):737-45. Epub 2015 mai 25
PMID: 26006015
Peripheral Blood Cells from Patients with Autoimmune Addison's Disease Poorly Respond to Interferons In Vitro, Despite Elevated Serum Levels of Interferon-Inducible Chemokines.
J Interferon Cytokine Res 2015 Oct;35(10):759-70. Epub 2015 mai 15
PMID: 25978633
A European Emergency Card for adrenal insufficiency can save lives.
Eur J Intern Med 2015 Jan;26(1):75-6. Epub 2014 des 11
PMID: 25498511
Circadian hormone profiles and insulin sensitivity in patients with Addison's disease: a comparison of continuous subcutaneous hydrocortisone infusion with conventional glucocorticoid replacement therapy.
Clin Endocrinol (Oxf) 2015 Jul;83(1):28-35. Epub 2015 jan 12
PMID: 25400085
Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease--an association study and expression analysis.
Autoimmunity 2015 Mar;48(2):100-7. Epub 2014 okt 27
PMID: 25347332
Clinical and serologic parallels to APS-I in patients with thymomas and autoantigen transcripts in their tumors.
J Immunol 2014 Oct 15;193(8):3880-90. Epub 2014 sep 17
PMID: 25230752
A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1.
Clin Immunol 2014 Jul;153(1):220-7. Epub 2014 mai 2
PMID: 24792136
High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients.
J Immunol 2014 Sep 1;193(5):2118-26. Epub 2014 jul 25
PMID: 25063864
Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia.
Endocr Connect 2014;3(2):67-74. Epub 2014 apr 15
PMID: 24671123
The effect of types I and III interferons on adrenocortical cells and its possible implications for autoimmune Addison's disease.
Clin Exp Immunol 2014 Jun;176(3):351-62.
PMID: 24666275
Continuous subcutaneous hydrocortisone infusion versus oral hydrocortisone replacement for treatment of addison's disease: a randomized clinical trial.
J Clin Endocrinol Metab 2014 May;99(5):1665-74. Epub 2014 feb 11
PMID: 24517155
Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.
J Intern Med 2014 Feb;275(2):104-15. Epub 2013 des 16
PMID: 24330030
Autoantibodies targeting neurotransmitter biosynthetic enzymes in attention-deficit/hyperactivity disorder (ADHD).
Eur Child Adolesc Psychiatry 2014 Feb;23(2):115-7. Epub 2013 mai 28
PMID: 23712861
Immuno-endocrine interactions in autoimmune Addison’s disease
- Disputert:
- mars 2016
- Hovedveileder:
- Eirik Bratland
Autoimmunity and viral immunity in Addison's disease
- Disputert:
- november 2015
- Hovedveileder:
- Eystein Sverre Husebye
Genetics of autoimmune Addison's disease and congential adrenal hyperplasia
- Disputert:
- mars 2015
- Hovedveileder:
- Eystein Sverre Husebye
DNA methylation in adrenal gland physiology and pathology
- Disputert:
- mai 2015
- Hovedveileder:
- Marit Bakke
- Jakub Abramson Prosjektdeltaker
- Johan Svartberg Prosjektdeltaker
- Kristian J Fougner Prosjektdeltaker
- Siri Carlsen Prosjektdeltaker
- Bjørn Gunnar Nedrebø Prosjektdeltaker
- Anders Palmstrøm Jørgensen Prosjektdeltaker
- Martina Erichsen Prosjektdeltaker
- Kristian Løvås Prosjektdeltaker
- Richard Alexander Hellesen Ph.d.-kandidat
- Eirik Bratland Prosjektdeltaker
- Anette Susanne Bøe Wolff Prosjektdeltaker
- Bergithe Eikeland Oftedal Postdoktor
- Eystein Sverre Husebye Prosjektleder
- Anne Grethe Myhre Prosjektdeltaker
- Per Knappskog Prosjektdeltaker
- Martina M Erichsen Prosjektdeltaker
- Øyvind Bruserud Ph.d.-kandidat
- Martina Moter Erichsen Prosjektdeltaker
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