Carboxyl-ester lipase and human pancreatic disease: New insights in the exocrine-endocrine interplay
- Prosjektnummer
- 912057
- Ansvarlig person
- Anders Molven
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Åpen prosjektstøtte
- Helsekategori
- Metabolic and Endocrine
- Forskningsaktivitet
- 1. Underpinning
Dette er et basalmedisinsk forskningsprosjekt hvor brukermedvirkning ansees for lite relevant.
The hybrid allele 1 of carboxyl-ester lipase (CEL-HYB1) in Polish pediatric patients with chronic pancreatitis.
Pancreatology 2019 Jun;19(4):531-534. Epub 2019 apr 26
PMID: 31036489
α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration.
Cancers (Basel) 2019 Jun 01;11(6). Epub 2019 jun 1
PMID: 31159419
The role of the carboxyl ester lipase (CEL) gene in pancreatic disease.
Pancreatology 2018 Jan;18(1):12-19. Epub 2017 des 5
PMID: 29233499
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2
J Biol Chem 2018 Dec 14;293(50):19476-19491. Epub 2018 okt 12
PMID: 30315106
Associations between ABO blood groups and pancreatic ductal adenocarcinoma: influence on resection status and survival.
Cancer Med 2017 Jul;6(7):1531-1540. Epub 2017 mai 29
PMID: 28556564
Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling.
Sci Rep 2017 May 17;7(1):2046. Epub 2017 mai 17
PMID: 28515477
Tissue MicroRNA profiles as diagnostic and prognostic biomarkers in patients with resectable pancreatic ductal adenocarcinoma and periampullary cancers.
Biomark Res 2017;5():8. Epub 2017 feb 21
PMID: 28239461
Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer.
Pancreatology 2017 Jan - Feb;17(1):83-88. Epub 2016 okt 11
PMID: 27773618
A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer.
J Control Release 2016 Dec 10;243():172-181. Epub 2016 okt 12
PMID: 27744037
Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis.
PLoS One 2016;11(11):e0165567. Epub 2016 nov 1
PMID: 27802312
Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase.
Biochemistry 2016 Aug 23;55(33):4636-41. Epub 2016 aug 10
PMID: 27509211
Lipase Genetic Variants in Chronic Pancreatitis: When the End Is Wrong, All's Not Well.
Gastroenterology 2016 Jun;150(7):1515-8. Epub 2016 apr 29
PMID: 27133394
Genetic and cellular studies of carboxyl-ester lipase (CEL), a protein involved in exocrine and endocrine pancreatic disease
- Disputert:
- september 2018
- Hovedveileder:
- Anders Molven
Carboxyl-ester lipase in human pancreatic disease: A study with focus on genetics, glycosylation and ABO blood groups
- Disputert:
- september 2018
- Hovedveileder:
- Anders Molven
- Erling Tjora Prosjektdeltaker
- Khadija el Jellas Postdoktor
- Mark E. Lowe Prosjektdeltaker
- Anny Gravdal Ph.d.-kandidat
- Monica Dalva Ph.d.-kandidat
- Pål Rasmus Njølstad Prosjektdeltaker
- Bente Berg Johansson Prosjektdeltaker
- Karianne Fjeld Prosjektdeltaker
- Anders Molven Prosjektleder
- Mark Lowe Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest