Bone marrow homeostasis, homing and cancer: the role of stabilin scavenging receptors
- Prosjektnummer
- SFP1000-11
- Ansvarlig person
- Peter McCourt
- Institusjon
- Universitetssykehuset Nord-Norge
- Prosjektkategori
- postdoktorstipend
- Helsekategori
- Blood, Inflammatory and immune system
- Forskningsaktivitet
- 1. Underpinning
Not relevant to this project.
Not relevant to this application
This is a basic research project, so the relevance to any user group(s) is limited. However, it the has potential to improve bone-marrow transplant strategies in the future, at which time user participation will be more appropriate.
The role of CD44 in fetal and adult hematopoietic stem cell regulation.
Haematologica 2016 Jan;101(1):26-37. Epub 2015 nov 6
PMID: 26546504
Brief Report: Factors Released by Megakaryocytes Thrombin Cleave Osteopontin to Negatively Regulate Hematopoietic Stem Cells.
Stem Cells 2015 Jul;33(7):2351-7. Epub 2015 mai 15
PMID: 25865259
Isolation of murine bone marrow scavenging sinusoidal endothelial cells.
Methods Mol Biol 2015;1235():59-71.
PMID: 25388386
N-terminal pro-C-type natriuretic peptide in serum associated with bone destruction in patients with multiple myeloma.
Biomark Med 2015;9(7):679-89.
PMID: 26174842
Analyzing hematopoietic stem cell homing, lodgment, and engraftment to better understand the bone marrow niche.
Ann N Y Acad Sci 2014 Mar;1310():119-28. Epub 2014 jan 15
PMID: 24428368
Understanding the role of the microenvironment during definitive hemopoietic development.
Exp Hematol 2013 Sep;41(9):761-8. Epub 2013 jun 22
PMID: 23800491
Identification of adult endothelial stem cells with endothelial and hematopoietic reconstitution potential
http://dx.doi.org/10.1016/j.exphem.2016.06.050, 2016
Isolation of murine bone marrow scavenging sinusoidal endothelial cells.
Methods Mol Biol.1235:59-71 PMID25388386, 2015
Bone marrow endothelium: A system with hemogenic stem cells giving rise to blood vessels and hemopoietic stem cells.
Manuscript, 2015
Megakaryocyte released factors thrombin cleave osteopontin to negatively regulate hemopoietic stem cells
Submitted, 2015
The role of CD44 in fetal and adult hemopoietic stem cell regulation.
Submitted, 2015
Analyzing hematopoietic stem cell homing, lodgment, and engraftment to better understand the bone marrow niche.
Ann N Y Acad Sci. 2014 Jan 15. [Epub ahead of print].
The isolation of murine bone marrow scavenging sinusoidal scavenging endothelial cells.
Submitted
The role of CD44 in hemopoietic stem cell regulation during ontogeny.
Submitted
Bone marrow endothelium: A system with hemogenic stem cells giving rise to blood vessels and hemopoietic stem cells.
Manuscript
BM endothelial stem cells are transplantable, giving rise to functional blood vessels as well as HSC.
Keystone Symposia: Hematopoiesis (A4), 2013-01-14-19
The role of megakaryocytes in hemopoietic stem cell regulation.
Keystone Symposia: Hematopoiesis (A4), 2013-01-14-19
Prospectively isolated scavenging bone-marrow sinusoidal endothelial cells home to & revascularize the BM of ablated recipients.
International Society for Cellular Therapy, 18th Annual Meeting (ISCT2012) 2012-06-05-2012-06-08
The role of freshly isolated megakaryocytes in haematopoietic stem cell regulation
Konferanse - 2011 - 40th Annual International Society of Experimental Haematology Meeting, Vancouver, Canada (poster)
Prospectively isolated scavenging bone-marrow sinusoidal endothelial cells home to and revascularise bone marrow
Konferanse - 2011 - 40th Annual International Society of Experimental Haematology Meeting, Vancouver, Canada (oral presentation - Nilsson)
Prospectively isolated sinusoidal bone-marrow sinusoidal endothelial cells home to and revascularise bone marrow
Konferanse - 2011 - Australian Stem Cell Centre 2011 Scientific Conference, Kingscliff, Australia (oral presentation - McCourt)
- Inger Marie Dahl Prosjektdeltaker
- Karen Kristine Sørensen Prosjektdeltaker
- Susan Nilsson Prosjektdeltaker
- Ana Oteiza Postdoktorstipendiat
- Peter McCourt Prosjektleder
- Susie Nilsson Prosjektdeltaker
- Anders Vik Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport, Helse Nord