Clinical Cancer Research Projects in The Tromsø Study
- Prosjektnummer
- SFP1273-16
- Ansvarlig person
- Inger Thune
- Institusjon
- UiT Norges arktiske universitet
- Prosjektkategori
- Flerårig forskningsprosjekt
- Helsekategori
- Cancer and neoplasms
- Forskningsaktivitet
- 4. Detection and Diagnosis, 5. Treatment Development
Brukerrepresentantene kan påvirke hvordan og når resultatene fra våre studier presenteres og det har de også utnyttet godt.
Vi har kontinuerlig kontakt med brukerrepresentanter både gjennom våre fagmøter - i våre studier, informasjonsmøter som holdes årlig og gjennom interesseorganisasjoner (Brystkreftforeningen og PROFO)
Brukermedvirkningen har vært problematisk grunnet Covid-19 pandemien da denne pandemien har forhindret oss i fysiske møter
Brukermedvirkning mhp prostata og brystkreft har i 2020 vært relatert til at vi har diskutert og hatt møter med brukerrepresentantene mhp viktige temaer de som brukere ønsker at vi skal ta med oss i forskningen. Dette resulterte blant annet at vi har sett på betydningen av flere livsstilsfaktorer samlet mhp brystkreft risiko og overlevelse. (publisert arbeid). For prostata resulterte dette i at vi har startet studier mhp. blodtrykkets betydning for prostatakreft risiko og prognose.
VI har flere ganger presentert våre to studier EBBA-life (brystkreft) og PROCA-life i medlemsmøter for brystkreftforeningen og prostakreftforeningen. Innspill fra disse brukerne har nå resultert i at vi blant annet fokuserer på betydningen av andre kroniske sykdommer i behandling og bivirkninger hos prostatakreft og brystkreftpasienter. Dette er planlagt å inngå i egne publikasjoner hvor dette studeres. Arbeidet er påbegynt.
Pasienter med prostatakreft og brystkreft er med i i prosjektets utvikling gjennom fagmøter og i spesifikke pasientmøter arrangert av interesseorganisasjoner
The Longitudinal Course of Prospectively Recorded Patient-reported Outcomes in Prostate Cancer Patients Treated with Surgery and Salvage Radiotherapy.
Eur Urol Open Sci 2023 Jul;53():6. Epub 2023 mai 13
PMID: 37441342
Patient-reported outcomes after curative treatment for prostate cancer with prostatectomy, primary radiotherapy or salvage radiotherapy.
Acta Oncol 2023 Jun;62(6):657. Epub 2023 jun 24
PMID: 37353983
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate.
Echocardiography 2023 Jul;40(7):623. Epub 2023 mai 22
PMID: 37211961
Expression of miR-24-1-5p in Tumor Tissue Influences Prostate Cancer Recurrence: The PROCA-
Cancers (Basel) 2022 Feb 23;14(5). Epub 2022 feb 23
PMID: 35267449
Systolic and diastolic blood pressure, prostate cancer risk, treatment, and survival. The PROCA-life study.
Cancer Med 2022 Feb;11(4):1005. Epub 2021 des 22
PMID: 34939344
Normal and unusual days for dietary intake during the 12 months after a breast cancer diagnosis in women.
Eur J Nutr 2022 Dec;61(8):3873. Epub 2022 jun 24
PMID: 35750881
The influence of metabolic factors and ethnicity on breast cancer risk, treatment and survival: The Oslo ethnic breast cancer study.
Acta Oncol 2022 May;61(5):649. Epub 2022 mar 29
PMID: 35348396
Do Breast Cancer Patients Manage to Participate in an Outdoor, Tailored, Physical Activity Program during Adjuvant Breast Cancer Treatment, Independent of Health and Socio-Demographic Characteristics?
J Clin Med 2022 Feb 05;11(3). Epub 2022 feb 5
PMID: 35160292
Joint effect of particulate matter and cigarette smoke on women's sex hormones.
BMC Womens Health 2022 Jan 08;22(1):3. Epub 2022 jan 8
PMID: 34996432
Inflammatory serum markers and risk and severity of prostate cancer: The PROCA-life study.
Int J Cancer 2020 Jul 01;147(1):84-92. Epub 2019 nov 20
PMID: 31583707
Exploring the effects of lifestyle on breast cancer risk, age at diagnosis, and survival: the EBBA-Life study.
Breast Cancer Res Treat 2020 Jul;182(1):215-227. Epub 2020 mai 20
PMID: 32436147
Chronic fatigue and associated factors among long-term survivors of cancers in young adulthood.
Acta Oncol 2019 May;58(5):753-762. Epub 2019 jan 30
PMID: 30696351
Lifestyle behavior among lymphoma survivors after high-dose therapy with autologous hematopoietic stem cell transplantation, assessed by patient-reported outcomes.
Acta Oncol 2019 May;58(5):690-699. Epub 2019 jan 30
PMID: 30696346
Continuing increased risk of second cancer in long-term testicular cancer survivors after treatment in the cisplatin era.
Int J Cancer 2019 Oct 09. Epub 2019 okt 9
PMID: 31597192
Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer.
Sci Rep 2019 Jul 23;9(1):10662. Epub 2019 jul 23
PMID: 31337863
MicroRNA 141 is associated to outcome and aggressive tumor characteristics in prostate cancer.
Sci Rep 2019 Jan 23;9(1):386. Epub 2019 jan 23
PMID: 30674952
Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes.
BMC Cancer 2018 Jun 15;18(1):654. Epub 2018 jun 15
PMID: 29902993
Validation of repeated self-reported n-3 PUFA intake using serum phospholipid fatty acids as a biomarker in breast cancer patients during treatment.
Nutr J 2018 10 17;17(1):94. Epub 2018 okt 17
PMID: 30333016
Metabolite and lipoprotein responses and prediction of weight gain during breast cancer treatment.
Br J Cancer 2018 Oct;119(9):1144-1154. Epub 2018 nov 7
PMID: 30401977
Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer.
NPJ Breast Cancer 2017;3():19. Epub 2017 mai 3
PMID: 28649659
The effect of exercise on fatigue and physical functioning in breast cancer patients during and after treatment and at 6 months follow-up: A meta-analysis.
Breast 2017 Jun;33():166-177. Epub 2017 apr 14
PMID: 28415013
Longitudinal and secular trends in total cholesterol levels and impact of lipid-lowering drug use among Norwegian women and men born in 1905-1977 in the population-based Tromsø Study 1979-2016.
BMJ Open 2017 Aug 21;7(8):e015001. Epub 2017 aug 21
PMID: 28827236
Bone mineral density is associated with vitamin D related rs6013897 and estrogen receptor polymorphism rs4870044: The Tromsø study.
PLoS One 2017;12(3):e0173045. Epub 2017 mar 2
PMID: 28253304
Association of occasional smoking with total mortality in the population-based Tromsø study, 2001-2015.
BMJ Open 2017 Dec 28;7(12):e019107. Epub 2017 des 28
PMID: 29288187
Human reproduction and health: an evolutionary perspective.
Lancet 2017 Jul 29;390(10093):510-520. Epub 2017 jul 27
PMID: 28792413
The relation between birthweight, childhood body mass index, and overweight and obesity in late adolescence: a longitudinal cohort study from Norway, The Tromsø Study, Fit Futures.
BMJ Open 2017 Jun 22;7(6):e015576. Epub 2017 jun 22
PMID: 28645970
Pre-diagnostic body mass index and weight change in relation to colorectal cancer survival among incident cases from a population-based cohort study.
BMC Cancer 2016 Jul 07;16():402. Epub 2016 jul 7
PMID: 27387027
The use and interpretation of anthropometric measures in cancer epidemiology: A perspective from the world cancer research fund international continuous update project.
Int J Cancer 2016 Dec 01;139(11):2391-7. Epub 2016 jul 13
PMID: 27352197
Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer.
Lipids Health Dis 2016 Mar 12;15():56. Epub 2016 mar 12
PMID: 26970778
Lack of support for relation between woman's masculinity preference, estradiol level and mating context.
Horm Behav 2016 Feb;78():1-7. Epub 2015 okt 21
PMID: 26497247
Polymorphisms in the estrogen receptor alpha gene (ESR1), daily cycling estrogen and mammographic density phenotypes.
BMC Cancer 2016 Oct 07;16(1):776. Epub 2016 okt 7
PMID: 27717337
Pre-diagnostic high-sensitive C-reactive protein and breast cancer risk, recurrence, and survival.
Breast Cancer Res Treat 2016 Jan;155(2):345-54. Epub 2016 jan 6
PMID: 26740213
Treatment of stage I seminoma, with one course of adjuvant carboplatin or surveillance, risk-adapted recommendations implementing patient autonomy: a report from the Swedish and Norwegian Testicular Cancer Group (SWENOTECA).
Ann Oncol 2016 Jul;27(7):1299-304. Epub 2016 apr 6
PMID: 27052649
Associations between long-term serum platinum and neurotoxicity and ototoxicity, endocrine gonadal function, and cardiovascular disease in testicular cancer survivors.
Urol Oncol 2016 Nov;34(11):487.e13-487.e20. Epub 2016 aug 11
PMID: 27523611
Effect of low or high glycemic load diets on experimentally induced mammary carcinogenesis in rats.
Mol Nutr Food Res 2016 Jun;60(6):1416-26. Epub 2016 mar 17
PMID: 26778091
Effects of vitamin D supplementation during weight loss on sex hormones in postmenopausal women.
Menopause 2016 Jun;23(6):645-52.
PMID: 26859343
Associations of sex steroid hormones with mortality in women with breast cancer.
Breast Cancer Res Treat 2016 Feb;155(3):559-67. Epub 2016 feb 10
PMID: 26865065
Dietary Weight Loss and Exercise Effects on Serum Biomarkers of Angiogenesis in Overweight Postmenopausal Women: A Randomized Controlled Trial.
Cancer Res 2016 Jul 15;76(14):4226-35.
PMID: 27417562
A novel non-canonical Wnt signature for prostate cancer aggressiveness.
Oncotarget 2017 Feb 07;8(6):9572-9586.
PMID: 28030815
Fibroblast miR-210 overexpression is independently associated with clinical failure in Prostate Cancer - a multicenter (in situ hybridization) study.
Sci Rep 2016 Nov 08;6():36573. Epub 2016 nov 8
PMID: 27824162
Assessing PDL-1 and PD-1 in Non-Small Cell Lung Cancer: A Novel Immunoscore Approach.
Clin Lung Cancer 2017 Mar;18(2):220-233.e8. Epub 2016 okt 5
PMID: 27816392
Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer.
Oncotarget 2016 Nov 01;7(44):72184-72196.
PMID: 27708229
Estrogen receptors a and ß and aromatase as independent predictors for prostate cancer outcome.
Sci Rep 2016 Sep 09;6():33114. Epub 2016 sep 9
PMID: 27610593
Presence of TMPRSS2-ERG is associated with alterations of the metabolic profile in human prostate cancer.
Oncotarget 2016 Jul 05;7(27):42071-42085.
PMID: 27276682
Prognostic relevance of estrogen receptor a, ß and aromatase expression in non-small cell lung cancer.
Steroids 2016 Sep;113():5-13. Epub 2016 mai 24
PMID: 27234503
The Role of Tumor-Infiltrating Lymphocytes in Development, Progression, and Prognosis of Non-Small Cell Lung Cancer.
J Thorac Oncol 2016 Jun;11(6):789-800. Epub 2016 feb 1
PMID: 26845192
Primary cervical cancer screening with an HPV mRNA test: a prospective cohort study.
BMJ Open 2016 Aug 11;6(8):e011981. Epub 2016 aug 11
PMID: 27515759
The Association Between Adiponectin, Serum Uric Acid and Urinary Markers of Renal Damage in the General Population: Cross-Sectional Data from the Tromsø Study.
Kidney Blood Press Res 2016;41(5):623-634. Epub 2016 sep 14
PMID: 27622764
Persistent analgesic use and the association with chronic pain and other risk factors in the population-a longitudinal study from the Tromsø Study and the Norwegian Prescription Database.
Eur J Clin Pharmacol 2016 Aug;72(8):977-85. Epub 2016 apr 12
PMID: 27071993
Burden of Cancer in a Large Consortium of Prospective Cohorts in Europe.
J Natl Cancer Inst 2016 Oct;108(10). Epub 2016 mai 6
PMID: 27154917
Cyclic endogenous estrogen and progesterone vary by mammographic density phenotypes in premenopausal women.
Eur J Cancer Prev 2016 Jan;25(1):9-18.
PMID: 25714648
Inflammation, hypertension, and microRNA and Prostate Cancer. The Prostate Cancer throughout life (PROCA-life) study
- Disputert:
- mars 2022
- Hovedveileder:
- Elin Richardsen
- Henrik Schirmer Prosjektdeltaker
- Egil Støre Blix Prosjektdeltaker
- Vidar Gordon Flote Prosjektdeltaker
- Endre Gabrielsen Doktorgradsstipendiat
- Inger Thune Prosjektleder
- Edvard Giovannucci Prosjektdeltaker
- Anne Mctiernan Prosjektdeltaker
- Tone Nordøy Prosjektdeltaker
- Elin Richardsen Prosjektdeltaker
- Tore Knutsen Doktorgradsstipendiat
- Anne Elise Eggen Prosjektdeltaker
- Hanne Frydenberg Postdoktorstipendiat
- Tom Wilsgaard Prosjektdeltaker
- Trygve Lofterød Doktorgradsstipendiat
- Hege Sagstuen Haugnes Prosjektdeltaker
- Elin Mortensen Prosjektdeltaker
- Einar Stikbakke Doktorgradsstipendiat
- Anna Maria Wirsing Prosjektdeltaker
- Martin Støyten Doktorgradsstipendiat
- Stig Manfred Dalen Doktorgradsstipendiat
- Elin Synnøve Mortensen Prosjektdeltaker
- Helene Langberg Prosjektdeltaker
- Cathrine Muller-Stamont Prosjektdeltaker
- Ed Giovannucci Prosjektdeltaker
- Erik Wist Prosjektdeltaker
- Tore Knutsen Doktorgradsstipendiat
- Terje Risberg Prosjektdeltaker
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