From basal molecular immunopathology to new strategies in the biological treatment of inflammatory bowel disease
- Prosjektnummer
- SFP922-10
- Ansvarlig person
- Jon Florholmen
- Institusjon
- Universitetssykehuset Nord-Norge HF
- Prosjektkategori
- Flerårig forskningsprosjekt
- Helsekategori
- Inflammatory and immune system
- Forskningsaktivitet
- 4. Detection and Diagnosis
Normalization of mucosal cytokine gene expression levels predicts long-term remission after discontinuation of anti-TNF therapy in Crohn's disease.
Scand J Gastroenterol 2013 Mar;48(3):311-9. Epub 2013 jan 10
PMID: 23302000
The effect of adalimumab for induction of endoscopic healing and normalization of mucosal cytokine gene expression in Crohn's disease.
Scand J Gastroenterol 2012 Oct;47(10):1200-10. Epub 2012 aug 6
PMID: 22861799
Mucosal cytokine gene expression profiles as biomarkers of response to infliximab in ulcerative colitis.
Scand J Gastroenterol 2012 May;47(5):538-47.
PMID: 22486187
Candidate mucosal and surrogate biomarkers of inflammatory bowel disease in the era of new technology.
Scand J Gastroenterol 2011 Dec;46(12):1407-17. Epub 2011 nov 1
PMID: 22040230
TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation.
Cytokine 2011 Dec;56(3):633-40. Epub 2011 sep 25
PMID: 21945121
Results of the 2nd part Scientific Workshop of the ECCO. II: Measures and markers of prediction to achieve, detect, and monitor intestinal healing in inflammatory bowel disease.
J Crohns Colitis 2011 Oct;5(5):484-98. Epub 2011 aug 11
PMID: 21939926
The economic burden of TNFa inhibitors and other biologic treatments in Norway.
Clinicoecon Outcomes Res 2011;3():73-8. Epub 2011 mar 21
PMID: 21935335
Cytokine mRNA expression in steroid-naïve patients with ulcerative colitis.
Inflamm Bowel Dis 2010 May;16(5):734.
PMID: 19653287
Continuous therapy with certolizumab pegol maintains remission of patients with Crohn's disease for up to 18 months.
Clin Gastroenterol Hepatol 2010 Jul;8(7):600-9. Epub 2010 feb 1
PMID: 20117244
Total and cause-specific mortality rates in a prospective study of community-acquired hepatitis C virus infection in northern Norway.
J Viral Hepat 2010 Mar. Epub 2010 mar 8
PMID: 20337923
Short and long term clinical outcome of infliximab in fulminant ulcerative colitis.
Ulcers. 2011: Volume 2011, Article ID 156407, 7 pages. doi:10.1155/2011/156407.
. Clinical, biological, and laboratory parameters as predictors of severity of clinical outcome and response to anti-TNF-alpha t
Ulcerative Colitis - Treatments, Special Populations and the Future, Ed. Mortimer O'Connor. 2011. ISBN 978-953-307-739-0
IL-17 gene expression in colorectal mucosa as a predictor of remission after induction therapy with infliximab in ulcerative col
Inflammatory Bowel Diseases 2011, suppl vol 17, 1, s16
Mucosal TNF-alpha levels in Crohn’s disease treated with adalimumab to an apparently healed mucosa, and the impact on time to re
Inflammatory Bowel Diseases 2011, suppl vol 17, 1, s37
TH1 and TH2 interactions in untreated inflamed mucosa of IBD, and their potential to mediate the inflammation.
Inflammatory Bowel Diseases 2011, suppl vol 17, 1, s16
TH1 and TH2 interactions in untreated inflamed mucosa of IBD, and their potential to mediate the inflammation.
Submitted Cytokine 2010
Mucosal TNF-alpha as a criterion when to stop treatment with anti TNF in UC patients?
Abstract ECCHO, Dublin 24-26 feb 2011
Mucosal TNF-alpha level as a criterion for when to discontinue treatment with adalimumab in patients with Crohn’s disease?
Abstract ECCHO, Dublin 24-26 feb 2011
Short and long term clinical outcome of infliximab in fulminant ulcerative colitis
Abstract ECCO, Dublin 24-26. febr 2011
Short and long term clinical outcome of infliximab in fulminant ulcerative colitis
Ulcers 2010, in press
Mucosal cytokine profiles as biomarkers in IBD
- Disputert:
- januar 2013
- Hovedveileder:
- Jon Florholmen
- Christopher Graham Fenton Prosjektdeltaker
- Ruth H Paulssen Prosjektdeltaker
- Odd Sverre Moen Prosjektdeltaker
- Ingrid Christiansen Prosjektdeltaker
- Mona Dixon Gundersen Doktorgradsstipendiat
- Richard Heitmann Doktorgradsstipendiat
- Trine Olsen Doktorgradsstipendiat
- Jon Florholmen Prosjektleder
- Guanglin Cui Prosjektdeltaker
- Rasmus Goll Doktorgradsstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport, Helse Nord