Free plasma hemoglobin and thrombosis: Novel aspects of pathogenesis and treatment.
- Prosjektnummer
- SFP985-10
- Ansvarlig person
- John-Bjarne Hansen
- Institusjon
- Universitetssykehuset Nord-Norge HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Blood
- Forskningsaktivitet
- 1. Underpinning
BMP-2 inhibits TF expression in human monocytes by shutting down MAPK signaling and AP-1 transcriptional activity.
Thromb Res 2012 Apr;129(4):e106-11. Epub 2011 nov 25
PMID: 22119392
Circulating monocytes mirror the imbalance in TF and TFPI expression in carotid atherosclerotic plaques with lipid-rich and calcified morphology.
Thromb Res 2012 Apr;129(4):e134-41. Epub 2011 des 15
PMID: 22178066
Evidence for direct transfer of tissue factor from monocytes to platelets in whole blood.
Blood Coagul Fibrinolysis 2012 Jun;23(4):345-50.
PMID: 22343684
The role of tissue factor in systemic inflammatory response syndrome.
Blood Coagul Fibrinolysis 2011 Sep;22(6):451-6.
PMID: 21597365
Increased expression of TF in BMP-7-treated human mononuclear cells depends on activation of select MAPK signaling pathways.
Thromb Res 2011 Dec;128(6):e154-9. Epub 2011 aug 6
PMID: 21820697
Low thrombogenicity of calcified atherosclerotic plaques is associated with bone morphogenetic protein-2-dependent inhibition of tissue factor expression.
Blood Coagul Fibrinolysis 2011 Dec;22(8):642-50.
PMID: 21897206
Platelets sense the hemolysis by P2Y12 receptor and activate TF expression in monocytes via P-selectin/PSGL-1 interaction
submitted, 2013
- Timophey Sovershaev Prosjektdeltaker
- Mikhail Sovershaev Prosjektdeltaker
- Elena Egorina Postdoktorstipendiat
- John-Bjarne Hansen Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport, Helse Nord